Article
Food Science & Technology
Hasan Nasiri, Hamed Baghban, Reza Teimuri-Mofrad, Ahad Mokhtarzadeh
Summary: Graphitic carbon nitride supported on magnetic chitosan was synthesized and used as a support for cellobiose dehydrogenase immobilization and as a modifier for glassy carbon electrode in the fabrication of an electrochemical lactose sensor. The composite exhibited excellent electrochemical performance and was successfully applied in lactose quantification in dairy products.
INTERNATIONAL DAIRY JOURNAL
(2023)
Article
Chemistry, Analytical
Hassan Nasrollahpour, Balal Khalilzadeh, Abdolhossein Naseri, Shahab Mamaghani, Ibrahim Isildak, Mohammad-Reza Rashidi
Summary: A green protocol based on chitosan-silver nanoparticles was developed for ultrasensitive recognition of PSA using the ECL effect of luminol. The electrodeposition of AuNPs and CS-AgNPs-luminol on the glassy carbon electrode resulted in a transducing surface with low-cost preparation and ultrafast determination. The use of AgNPs as a linker and amplifier, along with the addition of AuNPs, led to the successful detection of PSA in unprocessed serum samples.
Article
Chemistry, Analytical
Viktorija Teiserskyte, Jaunius Urbonavicius, Dalius Ratautas
Summary: This study reported the construction of a direct electron transfer biosensor based on NAD-dependent formaldehyde dehydrogenase, achieving a fast, highly sensitive detection of formaldehyde with high stability and selectivity.
Article
Multidisciplinary Sciences
Hucheng Chang, Neus Gacias Amengual, Alexander Botz, Lorenz Schwaiger, Daniel Kracher, Stefan Scheiblbrandner, Florian Csarman, Roland Ludwig
Summary: This study demonstrates the activity of Lytic polysaccharide monooxygenase (LPMO) on wood cell walls and suggests that even low levels of hydrogen peroxide can support the enzymatic degradation of wood biomass. LPMO plays a synergistic role in fungal extracellular catabolism and industrial biomass degradation.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Yanqun Chen, Min Zhou, Jinhua Yang, Yueming Tan, Wenfang Deng, Qingji Xie
Summary: This study presents a new strategy for sensitive PEC immunoassay by modifying the surface charge of photoactive materials. By utilizing CaCO3 nanoparticles as labels to regulate the surface charge of CdS@HMP QDs, sensitive detection of CEA is achieved with a linear detection range of 0.005-50 ng mL(-1) and a detection limit of 1 pg mL(-1).
ANALYTICAL CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Wenhao Qian, Tao Song, Mao Ye, Xiaoyu Huang, Yongjun Li, Bingjie Hao
Summary: In this study, a platform for gold nanoparticles (AuNPs) was developed, which maintained good dispersity and inherent physicochemical property. The nanocomposite, consisting of AuNPs and a functional dye, exhibited fluorescence properties and could be used as an efficient electrochemical sensor for glucose determination.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2022)
Article
Electrochemistry
Kavita Jayakumar, Thomas M. B. Reichhart, Christopher Schulz, Roland Ludwig, Alfons K. G. Felice, Donal Leech
Summary: Cellobiose dehydrogenase (CDH) is a biocatalyst capable of oxidizing cellobiose and related carbohydrates to generate electrical current. A novel engineered CDH has shown improved performance as a bioelectrocatalyst in glucose biosensors.
Article
Chemistry, Physical
Shengyuan Yao, Yan Lv, Qing Wang, Jinhui Yang, Hongmei Li, Ningning Gao, Furu Zhong, Jihong Fu, Jun Tang, Tao Wang, Dianzeng Jia
Summary: As a new 2D carbon allotrope, graphdiyne (GDY) with its unique electronic space arrangement structure has the characteristics of uniform pores and large specific surface area. A novel gold nanoparticles (Au NPs)/GDY/carbon cloth (CC) SERS substrate was fabricated using GDY nanowall as support. The substrate showed good sensitivity in detecting organic dyes.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Zedong Li, Shuang Wu, Jingcheng Ji, Yuemeng Bai, Pengpeng Jia, Yan Gong, Shangsheng Feng, Fei Li
Summary: Lateral flow assays (LFAs), a popular point-of-care testing platform, have limited detection sensitivity. This study developed a ball pen writing-without-ink method to amplify the detection signal, resulting in improved sensitivity.
Article
Chemistry, Analytical
Mohammadreza Farrokhnia, Ghassem Amoabediny, Mohammad Ebrahimi, Mohammadreza Ganjali, Mohammad Arjmand
Summary: An ultrsensitive novel electrochemical nano-biosensor was developed for rapid detection of insulin antibodies against diabetes antigens. The nano-biosensor exhibited high sensitivity, good reproducibility, and the potential for early detection of type 1 diabetes.
Article
Chemistry, Analytical
Yuanyuan Li, Dongmei Deng, Huan Wang, Ke Huan, Xiaoxia Yan, Liqiang Luo
Summary: In this study, morphology-controlled Cu-Sn alloy nanosheet arrays were fabricated using a facile electrodeposition technique, and they exhibited high specific surface energy and abundant active sites. The Cu-Sn/CP electrode served as a self-supported electrode for efficient nonenzymatic glucose sensing with wide linear ranges, low detection limit, excellent selectivity, and stability.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Lei Jiang, Cai-Hong He, Hua-Ying Chen, Cheng-Ye Xi, Essy Kouadio Fodjo, Ze-Rui Zhou, Ruo-Can Qian, Da-Wei Li, Mahmoud Elsayed Hafez
Summary: A highly anti-interference ZIF-8-based SERS sensor was developed for detecting H2O2 released from living cells, with a low detection limit of 0.357 nM and a response time as short as 1 minute. The sensor also enables real-time monitoring of H2O2 secreted from cells under stimulation, showing promising potential for future applications.
ANALYTICAL CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Muamer Dervisevic, Maria Alba, Lars Esser, Nazia Tabassum, Beatriz Prieto-Simon, Nicolas H. Voelcker
Summary: Wearable technologies have potential in health monitoring and diagnostics, with wearable sensors gaining increased research interest. A proposed solution using micropillar array surfaces to protect enzyme layers shows promise in glucose monitoring, offering a user-friendly, cost-effective, and reliable platform for sweat analysis to aid in health monitoring applications.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Guangna Ji, Wenyan Zhu, Xuexia Jia, Shuaifeng Ji, Dianpeng Han, Zhixian Gao, Hui Liu, Yu Wang, Tie Han
Summary: Effective and real-time detection of lactate (LA) content in human sweat has gained significant attention. A novel electrochemical paper-based analysis device (ePAD) was developed for non-invasive detection of LA in sweat. The study investigated the electrocatalytic properties of AuNP/Cu-TCPP(Fe) hybrid nanosheets and optimized the lactate sensor for usability and interpretability. The ePAD showed superior biocompatibility, accuracy, and high sensitivity, making it applicable for long-term monitoring of sweat LA concentrations in various extreme environments.
Article
Chemistry, Analytical
Yulan Tian, Ping Zhu, Yating Chen, Xiaoyu Bai, Liping Du, Wei Chen, Chunsheng Wu, Ping Wang
Summary: In this study, a novel piezoelectric aptasensor was designed for the detection of OA, with aptamers and quartz crystal microbalance used for signal detection, and gold nanoparticles for signal amplification. The biosensor showed a wide linear detection range and low detection limit.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Review
Chemistry, Multidisciplinary
Evgeny Katz, Paolo Bollella
Summary: This review summarizes the history and state-of-the-art in the areas of fuel and biofuel cells, aiming at a broad audience including experts, newcomers and students. While some parts are general and aimed at students, sections related to biofuel cells are more specialized and will be interesting for researchers. The article represents the personal opinions of the authors and aims at providing interesting and easy to read material, focusing more on concepts than specific experimental data. If readers get excited about the topic, the authors' goals will be satisfied.
ISRAEL JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Cristina Tortolini, Eliana Capecchi, Federico Tasca, Riccardo Pofi, Mary Anna Venneri, Raffaele Saladino, Riccarda Antiochia
Summary: Nanocomposites based on lignin nanoparticles were designed for electrochemical biosensing, showing strong inhibition effect on electron transfer reaction. The modified electrodes assembled with biosensors successfully demonstrated sensitivity towards glucose, with the three-layered structure exhibiting the best analytical performance.
Review
Chemistry, Analytical
Riccarda Antiochia
Summary: This review summarizes the current state of paper-based biosensors (PBBs) used in the detection of COVID-19, specifically focusing on three categories for SARS-CoV-2 diagnostics. It highlights the characteristics, analytical performance, advantages and drawbacks of each type of biosensor compared to traditional methods, with the hope of assisting scientists in developing novel PBB platforms with enhanced performance to help contain the COVID-19 outbreak.
Article
Chemistry, Analytical
Lucia Sarcina, Giuseppe Felice Mangiatordi, Fabrizio Torricelli, Paolo Bollella, Zahra Gounani, Ronald Osterbacka, Eleonora Macchia, Luisa Torsi
Summary: The study developed a reliable and label-free detection method for HIV-1 p24 protein using multi-parameter SPR. Different antibody immobilization techniques on the surface led to varying coverage and binding signals. The chemically modified system showed improved sensitivity and selectivity in detecting HIV-1 p24.
Article
Chemistry, Analytical
Cristina Tortolini, Federico Tasca, Mary Anna Venneri, Cinzia Marchese, Riccarda Antiochia
Summary: The study investigated the effects of nanostructured modifications of a gold electrode surface on the development of electrochemical sensors for L-ascorbic acid detection. By modifying a gold electrode with gold single-walled carbon nanotubes (Au/SWCNTs) and highly nanoporous gold (h-nPG) film, the sensors demonstrated enhanced sensitivity and lower detection limits compared to a bare gold electrode. The h-nPG electrode, in particular, was successfully used for ascorbic acid detection in human urine with satisfactory recovery levels and minimal interference.
Article
Chemistry, Multidisciplinary
D. Massana Roquero, P. Bollella, O. Smutok, E. Katz, A. Melman
Summary: This biocompatible drug delivery system shows a highly sensitive stimuli-responsive behavior to hydrogen peroxide, effectively releasing encapsulated proteins through oxidative degradation of boronate esters. The release can be triggered by low concentrations of hydrogen peroxide and can also be induced by incorporating oxidase enzymes in the presence of their substrates, serving as biomarkers for physiological disorders.
MATERIALS TODAY CHEMISTRY
(2021)
Review
Biochemical Research Methods
Galina Pankratova, Paolo Bollella, Dmitry Pankratov, Lo Gorton
Summary: This article introduces the recent advancements of supercapacitive biofuel cells (SBFCs), summarizes the performance of different types of SBFCs, and highlights their potential as promising "alternative" energy devices.
CURRENT OPINION IN BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Valeria Gigli, Davide Piccinino, Daniele Avitabile, Riccarda Antiochia, Eliana Capecchi, Raffaele Saladino
Summary: The overproduction of eumelanin can result in unaesthetic hyper-pigmented skin diseases. The current treatment methods, such as tyrosinase inhibitors, have harmful side effects. This study found that using laccase from Trametes versicolor and natural phenol redox mediators can efficiently degrade eumelanin, providing an alternative to traditional whitening agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Angelo Tricase, Anna Imbriano, Nicoletta Ditaranto, Eleonora Macchia, Rosaria Anna Picca, Davide Blasi, Luisa Torsi, Paolo Bollella
Summary: This study combines electrochemical and XPS experiments to investigate the conformational rearrangement of self-assembled monolayers (SAMs) on an electrode surface due to the application of an electrical field. It was found that activation and deactivation processes play a crucial role in reaction yields and conformational rearrangement, ultimately impacting the performance of bioelectronic devices.
Article
Chemistry, Analytical
Valeria Gigli, Cristina Tortolini, Eliana Capecchi, Antonio Angeloni, Andrea Lenzi, Riccarda Antiochia
Summary: In this study, a reliable biosensor was developed using chitosan nanoparticles and tyrosinase for accurate detection of total catecholamine levels in human urine samples. Through optimization of loading methods and enzyme concentration, the biosensor exhibited good stability and sensitivity.
Article
Chemistry, Physical
Sergio Choque, Cesar Zuniga, Alberto Gonzalez, Alejandra Moenne, Riccarda Antiochia, Lo Gorton, Federico Tasca
Summary: Three different macroalgae, U. lactuca, U. linza, and U. compressa, were studied for biological photovoltaic energy system (BPVE) using edge plane pyrolytic graphite as the working electrode. The biophotoanodes were evaluated for direct and mediated electron transfer processes using different mediators. The results showed that using p-benzoquinone (BQ) as a mediator during the mediated electron transfer process significantly increased the electron transfer to the graphite electrode during light conditions.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Analytical
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Luciano Galantini, Federico Tasca, Riccarda Antiochia
Summary: In this work, a simple electrochemical immunosensor was developed for the detection of D-dimer protein in human plasma samples. The immunosensor was constructed by drop-casting chitosan nanoparticles (CSNPs) as a biocompatible support, Protein A (PrA) to facilitate antibody orientation, and D-dimer antibody onto a carboxyl functionalized multi-walled carbon nanotubes screen printed electrode (MWCNTs-SPE). The immunosensor showed promising performance in antibody immobilization and specific D-dimer detection, with a linear range from 2 to 500 μg L-1, LOD of 0.6 μg L-1, and sensitivity of 1.3 μA L μg(-1) cm(-2). The stability and fast response time (5 s) were also reported. Moreover, the immunosensor demonstrated satisfactory results in detecting D-dimer in human plasma samples.
Article
Chemistry, Analytical
Cristina Tortolini, Valeria Gigli, Flavio Rizzo, Andrea Lenzi, Mariano Bizzarri, Antonio Angeloni, Riccarda Antiochia
Summary: This paper describes the development of a simple voltammetric biosensor for the stereoselective discrimination of myo-inositol and D-chiro-inositol by means of bovine serum albumin adsorption onto a multi-walled carbon nanotube graphite screen-printed electrode.
Article
Materials Science, Multidisciplinary
Daniel Massana Roquero, Paolo Bollella, Evgeny Katz, Artem Melman
Summary: The high porosity of calcium alginate hydrogels can be controlled by treatment with polyvinyl alcohol and cross-linking with diboronic acids, effectively blocking larger pores. This process reduces leaching of proteins trapped in the hydrogels by 20-30 fold, confirmed by microscopy techniques.
ACS APPLIED POLYMER MATERIALS
(2021)