标题
Genetics of rheumatoid arthritis susceptibility, severity, and treatment response
作者
关键词
-
出版物
Seminars in Immunopathology
Volume 39, Issue 4, Pages 395-408
出版商
Springer Nature
发表日期
2017-05-29
DOI
10.1007/s00281-017-0630-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis
- (2016) Chikashi Terao et al. Annual Review of Genomics and Human Genetics
- Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery
- (2016) Annie Yarwood et al. Expert Opinion on Drug Discovery
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Update on the genetic architecture of rheumatoid arthritis
- (2016) Kwangwoo Kim et al. Nature Reviews Rheumatology
- Family history of rheumatoid arthritis: an old concept with new developments
- (2016) Thomas Frisell et al. Nature Reviews Rheumatology
- Previously reported PDE3A–SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort
- (2016) Samantha Louise Smith et al. PHARMACOGENOMICS
- A genome-wide association study identifiesSLC8A3as a susceptibility locus for ACPA-positive rheumatoid arthritis
- (2016) Antonio Julià et al. RHEUMATOLOGY
- Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
- (2016) Solveig K. Sieberts et al. Nature Communications
- Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis
- (2016) Sebastien Viatte et al. Arthritis & Rheumatology
- Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis
- (2016) Sebastien Viatte et al. Arthritis & Rheumatology
- HLA-DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis
- (2016) Stephanie F. Ling et al. Arthritis & Rheumatology
- The role of genetic variants in CRP in radiographic severity in African Americans with early and established rheumatoid arthritis
- (2015) M I Danila et al. GENES AND IMMUNITY
- New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
- (2015) S Hong Lee et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Association of HLA-DRB1 Haplotypes With Rheumatoid Arthritis Severity, Mortality, and Treatment Response
- (2015) Sebastien Viatte et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?
- (2015) I. C. Scott et al. JOURNAL OF RHEUMATOLOGY
- Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study
- (2015) D. P. C. de Rooy et al. JOURNAL OF RHEUMATOLOGY
- Super-enhancers delineate disease-associated regulatory nodes in T cells
- (2015) Golnaz Vahedi et al. NATURE
- Genetics of rheumatoid arthritis in Asia—present and future
- (2015) Kazuhiko Yamamoto et al. Nature Reviews Rheumatology
- Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis
- (2015) A Ferreiro-Iglesias et al. PHARMACOGENOMICS JOURNAL
- C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis
- (2015) Munitta Muthana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis
- (2015) Hanna W van Steenbergen et al. ARTHRITIS RESEARCH & THERAPY
- PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts
- (2015) Luis Rodriguez-Rodriguez et al. ARTHRITIS RESEARCH & THERAPY
- Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population
- (2015) Chikashi Terao et al. ARTHRITIS RESEARCH & THERAPY
- Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci
- (2015) Paul Martin et al. Nature Communications
- TRAF1/C5but NotPTPRCVariants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy
- (2015) Helena Canhão et al. Biomed Research International
- Association of Valine and Leucine at HLA-DRB1 Position 11 With Radiographic Progression in Rheumatoid Arthritis, Independent of the Shared Epitope Alleles but Not Independent of Anti-Citrullinated Protein Antibodies
- (2015) H. W. van Steenbergen et al. Arthritis & Rheumatology
- Management of advanced non-small cell lung cancers with known mutations or rearrangements: latest evidence and treatment approaches
- (2015) Meghan Shea et al. Therapeutic Advances in Respiratory Disease
- Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
- (2014) Buhm Han et al. AMERICAN JOURNAL OF HUMAN GENETICS
- SPP1rs9138 variant contributes to the severity of radiological damage in anti-citrullinated protein autoantibody-negative rheumatoid arthritis
- (2014) Pierre-Antoine Juge et al. ANNALS OF THE RHEUMATIC DISEASES
- Estimation of heritability of different outcomes for genetic studies of TNFi response in patients with rheumatoid arthritis
- (2014) Maša Umićević Mirkov et al. ANNALS OF THE RHEUMATIC DISEASES
- A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
- (2014) L Bossini-Castillo et al. ANNALS OF THE RHEUMATIC DISEASES
- Biologic Therapies in Rheumatoid Arthritis and the Risk of Opportunistic Infections: A Meta-analysis
- (2014) Irene S. Kourbeti et al. CLINICAL INFECTIOUS DISEASES
- Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations
- (2014) Yukinori Okada et al. HUMAN MOLECULAR GENETICS
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Genetic and epigenetic predictors of responsiveness to treatment in RA
- (2014) Darren Plant et al. Nature Reviews Rheumatology
- Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis shows multiple novel risk variants and leads for TYMS regulation
- (2014) Sabyasachi Senapati et al. Pharmacogenetics and Genomics
- Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases
- (2014) J Cobb et al. PHARMACOGENOMICS JOURNAL
- Pre-Treatment Whole Blood Gene Expression Is Associated with 14-Week Response Assessed by Dynamic Contrast Enhanced Magnetic Resonance Imaging in Infliximab-Treated Rheumatoid Arthritis Patients
- (2014) Kenzie D. MacIsaac et al. PLoS One
- Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort
- (2014) James Bluett et al. RHEUMATOLOGY
- The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA: Table 1
- (2014) Annie Yarwood et al. RHEUMATOLOGY
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
- (2014) T. Raj et al. SCIENCE
- A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis
- (2014) Rachel Knevel et al. ARTHRITIS RESEARCH & THERAPY
- Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis
- (2014) Chun Li et al. ARTHRITIS RESEARCH & THERAPY
- Novel Risk Loci for Rheumatoid Arthritis in Han Chinese and Congruence With Risk Variants in Europeans
- (2014) Lei Jiang et al. Arthritis & Rheumatology
- Does a Genetic Variant inFOXO3APredict a Milder Course of Rheumatoid Arthritis?
- (2014) H. W. van Steenbergen et al. Arthritis & Rheumatology
- HLA-DRB1-Associated Rheumatoid Arthritis Risk at Multiple Levels in African Americans: Hierarchical Classification Systems, Amino Acid Positions, and Residues
- (2014) Richard J. Reynolds et al. Arthritis & Rheumatology
- Lack of association betweenIL-15genetic variants and progression of joint destruction in Japanese patients with rheumatoid arthritis
- (2013) Shinji Yoshida et al. ANNALS OF THE RHEUMATIC DISEASES
- A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk
- (2013) Annie Yarwood et al. ANNALS OF THE RHEUMATIC DISEASES
- Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation
- (2013) Pauline A van Schouwenburg et al. ANNALS OF THE RHEUMATIC DISEASES
- Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis
- (2013) Rachel Knevel et al. ANNALS OF THE RHEUMATIC DISEASES
- A genetic variant in the region ofMMP-9is associated with serum levels and progression of joint damage in rheumatoid arthritis
- (2013) D P C de Rooy et al. ANNALS OF THE RHEUMATIC DISEASES
- Brief Report: Identification ofBACH2andRAD51Bas Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data
- (2013) Kate McAllister et al. ARTHRITIS AND RHEUMATISM
- Brief Report: Association of Genetic Variants in theIL4andIL4RGenes With the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts
- (2013) A. Krabben et al. ARTHRITIS AND RHEUMATISM
- Association of Variants inIL2RAWith Progression of Joint Destruction in Rheumatoid Arthritis
- (2013) R. Knevel et al. ARTHRITIS AND RHEUMATISM
- Familial Risks and Heritability of Rheumatoid Arthritis: Role of Rheumatoid Factor/Anti-Citrullinated Protein Antibody Status, Number and Type of Affected Relatives, Sex, and Age
- (2013) Thomas Frisell et al. ARTHRITIS AND RHEUMATISM
- Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway
- (2013) James C. Lee et al. CELL
- Influence of interleukin-4 gene polymorphisms and interleukin-4 serum level on susceptibility and severity of rheumatoid arthritis in Egyptian population
- (2013) Yousri M. Hussein et al. CYTOKINE
- A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis
- (2013) Stephen W. Scally et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genome-wide significant association ofANKRD55rs6859219 and multiple sclerosis risk
- (2013) Christina M Lill et al. JOURNAL OF MEDICAL GENETICS
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
- (2013) Anne Hinks et al. NATURE GENETICS
- Genetics and epigenetics of rheumatoid arthritis
- (2013) Sebastien Viatte et al. Nature Reviews Rheumatology
- GWAS replication study confirms the association of PDE3A–SLCO1C1 with anti-TNF therapy response in rheumatoid arthritis
- (2013) Isabel Acosta-Colman et al. PHARMACOGENOMICS
- On the Origin of Rheumatoid Arthritis: The Impact of Environment and Genes—A Population Based Twin Study
- (2013) Anders J. Svendsen et al. PLoS One
- Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens
- (2013) Xiaoming Jia et al. PLoS One
- PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study
- (2013) Taku Suzuki et al. PLoS One
- Lack of Association of Variants Previously Associated with Anti-TNF Medication Response in Rheumatoid Arthritis Patients: Results from a Homogeneous Greek Population
- (2013) Maria I. Zervou et al. PLoS One
- Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis
- (2013) Jing Cui et al. PLoS Genetics
- Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome-Wide Association Study
- (2013) Gisela Orozco et al. Arthritis & Rheumatology
- Contribution of FunctionalLILRA3, but Not NonfunctionalLILRA3, to Sex Bias in Susceptibility and Severity of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis
- (2013) Yan Du et al. Arthritis & Rheumatology
- Development and Validation of Modified Disease Activity Scores in Rheumatoid Arthritis: Superior Correlation With Magnetic Resonance Imaging-Detected Synovitis and Radiographic Progression
- (2013) Joshua F. Baker et al. Arthritis & Rheumatology
- Improved Heritability Estimation from Genome-wide SNPs
- (2012) Doug Speed et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients
- (2012) Sebastien Viatte et al. ANNALS OF THE RHEUMATIC DISEASES
- Studying associations between variants inTRAF1-C5andTNFAIP3-OLIG3and the progression of joint destruction in rheumatoid arthritis in multiple cohorts
- (2012) R Knevel et al. ANNALS OF THE RHEUMATIC DISEASES
- Genetic variants inIL15associate with progression of joint destruction in rheumatoid arthritis: a multicohort study
- (2012) R Knevel et al. ANNALS OF THE RHEUMATIC DISEASES
- Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis
- (2012) Diederik P C de Rooy et al. ANNALS OF THE RHEUMATIC DISEASES
- Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: a population-based study
- (2012) Rachel Knevel et al. ANNALS OF THE RHEUMATIC DISEASES
- A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis
- (2012) R. Knevel et al. ARTHRITIS AND RHEUMATISM
- FCRL3 gene polymorphisms contribute to the radiographic severity rather than susceptibility of rheumatoid arthritis
- (2012) Seung Woo Han et al. HUMAN IMMUNOLOGY
- Investigation of Rheumatoid Arthritis Genetic Susceptibility Markers in the Early Rheumatoid Arthritis Study Further Replicates the TRAF1 Association with Radiological Damage
- (2012) S. VIATTE et al. JOURNAL OF RHEUMATOLOGY
- Rheumatoid Arthritis-associated Polymorphisms at 6q23 Are Associated with Radiological Damage in Autoantibody-positive RA
- (2012) J. R. MAXWELL et al. JOURNAL OF RHEUMATOLOGY
- High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
- (2012) Steve Eyre et al. NATURE GENETICS
- Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
- (2012) Soumya Raychaudhuri et al. NATURE GENETICS
- Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population
- (2012) Yukinori Okada et al. NATURE GENETICS
- Chromatin marks identify critical cell types for fine mapping complex trait variants
- (2012) Gosia Trynka et al. NATURE GENETICS
- A Replication Study Confirms the Association of Dendritic Cell Immunoreceptor (DCIR) Polymorphisms with ACPA - Negative RA in a Large Asian Cohort
- (2012) Jianping Guo et al. PLoS One
- CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis
- (2012) S. W. Han et al. TISSUE ANTIGENS
- Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis
- (2012) Erik JM Toonen et al. ARTHRITIS RESEARCH & THERAPY
- Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets
- (2011) Xinli Hu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort
- (2011) Darren Plant et al. ARTHRITIS AND RHEUMATISM
- Influence of TRAF1/C5 and STAT4 genes polymorphisms on susceptibility and severity of rheumatoid arthritis in Egyptian population
- (2011) Rasha H. Mohamed et al. CELLULAR IMMUNOLOGY
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic influences modulating the radiological severity of rheumatoid arthritis
- (2010) I. Marinou et al. ANNALS OF THE RHEUMATIC DISEASES
- A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis
- (2010) L. Padyukov et al. ANNALS OF THE RHEUMATIC DISEASES
- PTPRCrheumatoid arthritis risk allele is also associated with response to anti-TNF therapy
- (2010) Jing Cui et al. ARTHRITIS AND RHEUMATISM
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
- (2010) Eli A Stahl et al. NATURE GENETICS
- Ethnogenetic heterogeneity of rheumatoid arthritis—implications for pathogenesis
- (2010) Yuta Kochi et al. Nature Reviews Rheumatology
- The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register
- (2010) Darren Plant et al. RHEUMATOLOGY
- Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis
- (2009) H. U. Scherer et al. ANNALS OF THE RHEUMATIC DISEASES
- A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis
- (2009) B. Skinningsrud et al. ANNALS OF THE RHEUMATIC DISEASES
- Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions
- (2009) Kari Hemminki et al. ARTHRITIS AND RHEUMATISM
- Association of a single-nucleotide polymorphism inCD40with the rate of joint destruction in rheumatoid arthritis
- (2009) Michael P. M. van der Linden et al. ARTHRITIS AND RHEUMATISM
- Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner
- (2009) A. S. Dimas et al. SCIENCE
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