Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension

Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout MiceSignificance

(2016) Reut Shnerb Ganor et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

(2015) Harry R. Büller et al.   NEW ENGLAND JOURNAL OF MEDICINE

Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation

(2014) Adam Corken et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits

(2014) Jonathan W. Yau et al.   BLOOD

Angiotensin II–Induced Vascular Dysfunction Depends on Interferon-γ–Driven Immune Cell Recruitment and Mutual Activation of Monocytes and NK-Cells

(2013) Sabine Kossmann et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

2013 ESH/ESC Guidelines for the management of arterial hypertension

(2013)   EUROPEAN HEART JOURNAL

Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice

(2013) N. Yokota et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Immune mechanisms in angiotensin II-induced target-organ damage

(2012) Friedrich C. Luft et al.   ANNALS OF MEDICINE

Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis

(2012) E. I. Tucker et al.   BLOOD

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Hyperphosphataemia sensitizes renally impaired rats to the profibrotic effects of gadodiamide

(2011) N Fretellier et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lysozyme M–Positive Monocytes Mediate Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2011) Philip Wenzel et al.   CIRCULATION

P2X7 receptor signaling contributes to tissue factor–dependent thrombosis in mice

(2011) Christian Furlan-Freguia et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding

(2011) K. JURK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk

(2010) H. Zhang et al.   BLOOD

Activated monocytes capture platelets for heterotypic association in patients with severe carotid artery stenosis

(2010) Carsten Schriek et al.   THROMBOSIS AND HAEMOSTASIS

Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis

(2010) Ophira Salomon et al.   THROMBOSIS AND HAEMOSTASIS

Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials

(2009)   LANCET

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

(2008) E. I. Tucker et al.   BLOOD

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

(2008) O. Salomon et al.   BLOOD