Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers

Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial

(2016) Guido J. H. Bastiaens et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

(2016) Jona Walk et al.   MALARIA JOURNAL

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

(2015) Gloria P Gómez-Pérez et al.   MALARIA JOURNAL

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

(2015) Benjamin Mordmüller et al.   MALARIA JOURNAL

Ex vivolymphocyte phenotyping duringPlasmodium falciparumsporozoite immunization in humans

(2015) E. M. Bijker et al.   PARASITE IMMUNOLOGY

Patterns and dynamics of genetic diversity in Plasmodium falciparum: What past human migrations tell us about malaria

(2015) Toshihiro Mita et al.   PARASITOLOGY INTERNATIONAL

Cytotoxic Markers Associate With Protection Against Malaria in Human Volunteers Immunized WithPlasmodium falciparumSporozoites

(2014) Else M. Bijker et al.   JOURNAL OF INFECTIOUS DISEASES

Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report

(2014) Maurits PA van Meer et al.   MALARIA JOURNAL

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

(2014) Laurent Dembélé et al.   NATURE MEDICINE

Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial

(2014) Else M. Bijker et al.   PLoS One

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

(2013) E. M. Bijker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

(2012) Ashley M. Vaughan et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficacy of Preerythrocytic and Blood-Stage Malaria Vaccines Can Be Assessed in Small Sporozoite Challenge Trials in Human Volunteers

(2012) M. Roestenberg et al.   JOURNAL OF INFECTIOUS DISEASES

NF135.C10: A New Plasmodium falciparum Clone for Controlled Human Malaria Infections

(2012) Anne C. Teirlinck et al.   JOURNAL OF INFECTIOUS DISEASES

Comparison of Clinical and Parasitological Data from Controlled Human Malaria Infection Trials

(2012) Meta Roestenberg et al.   PLoS One

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

(2011) Meta Roestenberg et al.   LANCET

A biologist’s perspective on malaria vaccine development

(2010) Robert Sinden   Human vaccines & immunotherapeutics

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene Disruption of Plasmodium falciparum p52 Results in Attenuation of Malaria Liver Stage Development in Cultured Primary Human Hepatocytes

(2008) Ben C. L. van Schaijk et al.   PLoS One

Temperature Shift and Host Cell Contact Up-Regulate Sporozoite Expression of Plasmodium falciparum Genes Involved in Hepatocyte Infection

(2008) Anthony Siau et al.   PLoS Pathogens