A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation

(2016) Stefan Grüner et al.   MOLECULAR CELL

SLIRP stabilizes LRPPRC via an RRM–PPR protein interface

(2016) Henrik Spåhr et al.   NUCLEIC ACIDS RESEARCH

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

(2016) Laurent Volpon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

(2015) B. Culjkovic-Kraljacic et al.   BLOOD

A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

(2014) S. Assouline et al.   HAEMATOLOGICA

The Oncogene eIF4E: Using Biochemical Insights to Target Cancer

(2013) Martin Carroll et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

(2012) Biljana Culjkovic-Kraljacic et al.   Cell Reports

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

(2011) Benedetta Ruzzenente et al.   EMBO JOURNAL

Structural scaffold for eIF4E binding selectivity of 4E-BP isoforms: crystal structure of eIF4E binding region of 4E-BP2 and its comparison with that of 4E-BP1

(2011) Ai Fukuyo et al.   JOURNAL OF PEPTIDE SCIENCE

Cap-Assisted Internal Initiation of Translation of Histone H4

(2011) Franck Martin et al.   MOLECULAR CELL

LRPPRC is a mitochondrial matrix protein that is conserved in metazoans

(2010) Fredrik H. Sterky et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E

(2010) L. Volpon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin

(2009) S. Assouline et al.   BLOOD

Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

(2009) Ivan Topisirovic et al.   EMBO JOURNAL