Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

(2015) B. Culjkovic-Kraljacic et al.   BLOOD

Genetic and Pharmacologic Inhibition of eIF4E Reduces Breast Cancer Cell Migration, Invasion, and Metastasis

(2015) F. Pettersson et al.   CANCER RESEARCH

A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

(2014) S. Assouline et al.   HAEMATOLOGICA

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

(2014) Hiba Ahmad Zahreddine et al.   NATURE

Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate

(2013) Laurent Volpon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Oncogene eIF4E: Using Biochemical Insights to Target Cancer

(2013) Martin Carroll et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Structural Basis for Cell-Cycle-Dependent Nuclear Import Mediated by the Karyopherin Kap121p

(2013) Junya Kobayashi et al.   JOURNAL OF MOLECULAR BIOLOGY

Human inducible nitric oxide synthase (iNOS) expression depends on chromosome region maintenance 1 (CRM1)- and eukaryotic translation initiation factor 4E (elF4E)-mediated nucleocytoplasmic mRNA transport

(2013) Franziska Bollmann et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition

(2013) M. J. Osborne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

(2012) Biljana Culjkovic-Kraljacic et al.   Cell Reports

Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer

(2011) F. Pettersson et al.   CLINICAL CANCER RESEARCH

Nuclear import by karyopherin-βs: Recognition and inhibition

(2010) Yuh Min Chook et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin

(2009) S. Assouline et al.   BLOOD

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

(2009) Lasse Weinmann et al.   CELL

Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

(2009) Ivan Topisirovic et al.   EMBO JOURNAL

Preferential Utilization of Imp7/8 in Nuclear Import of Smads

(2008) Xiaohao Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The eIF4E RNA regulon promotes the Akt signaling pathway

(2008) Biljana Culjkovic et al.   JOURNAL OF CELL BIOLOGY