The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression

PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts

(2017) Sally Danno et al.   GENES TO CELLS

Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l

(2016) Anoush E. Anderson et al.   MOLECULAR AND CELLULAR BIOLOGY

Tgif1 and Tgif2 Regulate Axial Patterning in Mouse

(2016) Tiffany A. Melhuish et al.   PLoS One

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

(2016) Ivan Quétier et al.   Cell Reports

Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

(2015) Corina E. Antal et al.   CELL

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells

(2015) Cordula A. Jilg et al.   Oncotarget

Prostate Cancer Induced by Loss of Apc Is Restrained by TGFβ Signaling

(2014) Glen A. Bjerke et al.   PLoS One

Activation of Akt signaling in prostate induces a TGFβ-mediated restraint on cancer progression and metastasis

(2013) G A Bjerke et al.   ONCOGENE

Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic

(2012) Shazia Irshad et al.   CANCER AND METASTASIS REVIEWS

Regulatory Domain Selectivity in the Cell-Type Specific PKN-Dependence of Cell Migration

(2011) Sylvie Lachmann et al.   PLoS One

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

(2010) Won Jun Oh et al.   EMBO JOURNAL

Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation

(2009) Shannon E. Powers et al.   DEVELOPMENT

PRK1 distribution in normal tissues and carcinomas: overexpression and activation in ovarian serous carcinoma

(2009) Mary T. Galgano et al.   HUMAN PATHOLOGY

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

(2008) Tsuneo Ikenoue et al.   EMBO JOURNAL

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

(2008) Valeria Facchinetti et al.   EMBO JOURNAL

Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma

(2008) C. K. Ratnacaram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA