Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic
出版年份 2012 全文链接
标题
Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic
作者
关键词
Prostate cancer, Genetically engineered mice, GEM models
出版物
CANCER AND METASTASIS REVIEWS
Volume 32, Issue 1-2, Pages 109-122
出版商
Springer Nature
发表日期
2012-10-31
DOI
10.1007/s10555-012-9409-1
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model
- (2012) N. Floc'h et al. CANCER RESEARCH
- B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer
- (2012) J. Wang et al. CANCER RESEARCH
- Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells
- (2012) D. J. Mulholland et al. CANCER RESEARCH
- Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases
- (2012) Zhihu Ding et al. CELL
- The Role of SRC-1 in Murine Prostate Carcinogenesis Is Nonessential due to a Possible Compensation of SRC-3/AIB1 Overexpression
- (2012) Jean Ching-Yi Tien et al. International Journal of Biological Sciences
- Germline Mutations inHOXB13and Prostate-Cancer Risk
- (2012) Charles M. Ewing et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Hoxb13-driven reverse tetracycline transactivator system for conditional gene expression in the prostate
- (2012) Varsha Rao et al. PROSTATE
- Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression
- (2011) Muhan Chen et al. CANCER CELL
- Smooth Muscle Cell-Specific Knockout of Androgen Receptor: A New Model for Prostatic Disease
- (2011) Michelle Welsh et al. ENDOCRINOLOGY
- Conditional Expression of the Androgen Receptor Induces Oncogenic Transformation of the Mouse Prostate
- (2011) Chunfang Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia
- (2011) Helen B. Pearson et al. JOURNAL OF CLINICAL INVESTIGATION
- SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
- (2011) Zhihu Ding et al. NATURE
- A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53
- (2011) J Kim et al. ONCOGENE
- Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts
- (2011) Shengqiang Yu et al. PROSTATE
- Characterization of KRAS Rearrangements in Metastatic Prostate Cancer
- (2011) Xiao-Song Wang et al. Cancer Discovery
- Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors
- (2010) Jianfei Qi et al. CANCER CELL
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- SOX9 Elevation in the Prostate Promotes Proliferation and Cooperates with PTEN Loss to Drive Tumor Formation
- (2010) M. K. Thomsen et al. CANCER RESEARCH
- Molecular genetics of prostate cancer: new prospects for old challenges
- (2010) M. M. Shen et al. GENES & DEVELOPMENT
- Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
- (2010) Nallasivam Palanisamy et al. NATURE MEDICINE
- MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial Cells
- (2010) Tsuyoshi Iwata et al. PLoS One
- A constitutively activated form of the p110 isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice
- (2010) S. H. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hoxb13regulatory elements mediate transgene expression during prostate organogenesis and carcinogenesis
- (2009) Ryan P. McMullin et al. DEVELOPMENTAL DYNAMICS
- A luminal epithelial stem cell that is a cell of origin for prostate cancer
- (2009) Xi Wang et al. NATURE
- Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
- (2009) Jennifer C King et al. NATURE GENETICS
- Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
- (2009) Brett S Carver et al. NATURE GENETICS
- Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF- B activation and invasive prostate carcinoma
- (2009) P. J. Fernandez-Marcos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer
- (2009) Jongchan Kim et al. PLoS Genetics
- A Prostatic Intraepithelial Neoplasia-Dependent p27Kip1 Checkpoint Induces Senescence and Inhibits Cell Proliferation and Cancer Progression
- (2008) Pradip K. Majumder et al. CANCER CELL
- Conditional Deletion of Insulin-like Growth Factor-I Receptor in Prostate Epithelium
- (2008) B. W. Sutherland et al. CANCER RESEARCH
- Targeted Overexpression of Vav3 Oncogene in Prostatic Epithelium Induces Nonbacterial Prostatitis and Prostate Cancer
- (2008) Y. Liu et al. CANCER RESEARCH
- Stromal Transforming Growth Factor- Signaling Mediates Prostatic Response to Androgen Ablation by Paracrine Wnt Activity
- (2008) V. R. Placencio et al. CANCER RESEARCH
- The Nuclear Factor- B Pathway Controls the Progression of Prostate Cancer to Androgen-Independent Growth
- (2008) R. J. Jin et al. CANCER RESEARCH
- K-ras and Wnt Signaling Synergize to Accelerate Prostate Tumorigenesis in the Mouse
- (2008) H. B. Pearson et al. CANCER RESEARCH
- Sox9 is required for prostate development
- (2008) Martin K. Thomsen et al. DEVELOPMENTAL BIOLOGY
- Prostate development: a historical perspective
- (2008) Barry G. Timms DIFFERENTIATION
- Integrating differentiation and cancer: The Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis
- (2008) Cory Abate-Shen et al. DIFFERENTIATION
- Temporally controlled prostate epithelium-specific gene alterations
- (2008) H. Artee Luchman et al. GENESIS
- Targeting the stromal androgen receptor in primary prostate tumors at earlier stages
- (2008) Y. Niu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Androgen receptor is a tumor suppressor and proliferator in prostate cancer
- (2008) Y. Niu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma
- (2008) C. K. Ratnacaram et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A causal role for ERG in neoplastic transformation of prostate epithelium
- (2008) O. Klezovitch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of β-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration
- (2008) Xiuping Yu et al. PROSTATE
- Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer
- (2008) Scott A. Tomlins et al. NEOPLASIA
- Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer
- (2007) Teresa Chiaverotti et al. AMERICAN JOURNAL OF PATHOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now