Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

Solution Structures of Complement C2 and Its C4 Complexes Propose Pathway-specific Mechanisms for Control and Activation of the Complement Proconvertases

(2016) Sofia Mortensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions

(2016) Erika M. Cook et al.   JOURNAL OF IMMUNOLOGY

Complement activation, regulation, and molecular basis for complement-related diseases

(2015) G. Bajic et al.   EMBO JOURNAL

Structural Insights into the Initiating Complex of the Lectin Pathway of Complement Activation

(2015) Troels R. Kjaer et al.   STRUCTURE

Automated Pipeline for Purification, Biophysical and X-Ray Analysis of Biomacromolecular Solutions

(2015) Melissa A. Graewert et al.   Scientific Reports

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY)

(2015) Clement E. Blanchet et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

(2014) Søren E. Degn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Deciphering the Fine Details of C1 Assembly and Activation Mechanisms: “Mission Impossible”?

(2014) Christine Gaboriaud et al.   Frontiers in Immunology

Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites

(2013) I. Bally et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation

(2013) Umakhanth Venkatraman Girija et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Automated acquisition and analysis of small angle X-ray scattering data

(2012) Daniel Franke et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

Improvement of molecular-replacement models withSculptor

(2011) Gábor Bunkóczi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mapping Surface Accessibility of the C1r/C1s Tetramer by Chemical Modification and Mass Spectrometry Provides New Insights into Assembly of the Human C1 Complex

(2010) Sébastien Brier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3D Cryo-EM Structure of an Active Step I Spliceosome and Localization of Its Catalytic Core

(2010) Monika M. Golas et al.   MOLECULAR CELL

New insights into the molecular mechanisms of classical complement activation

(2010) Mihaela Kojouharova et al.   MOLECULAR IMMUNOLOGY

Identification of the C1q-binding Sites of Human C1r and C1s

(2009) Isabelle Bally et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved prediction of protein side-chain conformations with SCWRL4

(2009) Georgii G. Krivov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r

(2007) József Kardos et al.   MOLECULAR IMMUNOLOGY