Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast

Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase

(2016) Daniel R. Semlow et al.   CELL

Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase

(2016) J. S. Ang et al.   GENETICS

Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer

(2016) Supipi Duffy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A global genetic interaction network maps a wiring diagram of cellular function

(2016) M. Costanzo et al.   SCIENCE

Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck

(2016) Kie Kyon Huang et al.   Scientific Reports

The Spontaneous Mutation Rate in the Fission YeastSchizosaccharomyces pombe

(2015) Ashley Farlow et al.   GENETICS

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

(2015) Kin Chan et al.   NATURE GENETICS

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding

(2015) Hyo-eun C Bhang et al.   NATURE MEDICINE

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

(2015) Anders R Clausen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Dissecting genetic and environmental mutation signatures with model organisms

(2015) Romulo Segovia et al.   TRENDS IN GENETICS

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

(2015) Anders R Clausen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-Wide Mutational Signature of the Chemotherapeutic Agent Mitomycin C in Caenorhabditis elegans

(2015) Annie S. Tam et al.   G3-Genes Genomes Genetics

The Spontaneous Mutation Rate in the Fission YeastSchizosaccharomyces pombe

(2015) Ashley Farlow et al.   GENETICS

Synthetic Cytotoxicity: Digenic Interactions with TEL1/ATM Mutations Reveal Sensitivity to Low Doses of Camptothecin

(2014) Xuesong Li et al.   GENETICS

DNA Replication Error-Induced Extinction of Diploid Yeast

(2014) A. J. Herr et al.   GENETICS

The Yeast Deletion Collection: A Decade of Functional Genomics

(2014) Guri Giaever et al.   GENETICS

C. eleganswhole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

(2014) Bettina Meier et al.   GENOME RESEARCH

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

(2014) Terrence N. Wong et al.   NATURE

Quantitative analysis of triple-mutant genetic interactions

(2014) Hannes Braberg et al.   Nature Protocols

Understanding nucleotide excision repair and its roles in cancer and ageing

(2014) Jurgen A. Marteijn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutational landscape of yeast mutator strains

(2014) Alexandre Serero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

(2014) A. Y. Lee et al.   SCIENCE

Genome Destabilizing Mutator Alleles Drive Specific Mutational Trajectories in Saccharomyces cerevisiae

(2013) P. C. Stirling et al.   GENETICS

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Mechanisms of resistance to therapies targeting BRCA-mutant cancers

(2013) Christopher J Lord et al.   NATURE MEDICINE

pLogo: a probabilistic approach to visualizing sequence motifs

(2013) Joseph P O'Shea et al.   NATURE METHODS

Human polymerase kappa uses a template-slippage deletion mechanism, but can realign the slipped strands to favour base substitution mutations over deletions

(2013) P. Mukherjee et al.   NUCLEIC ACIDS RESEARCH

Repair of Strand Breaks by Homologous Recombination

(2013) M. Jasin et al.   Cold Spring Harbor Perspectives in Biology

Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy

(2013) Tanima SenGupta et al.   Nature Communications

DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions inSaccharomyces cerevisiae

(2012) Jana E. Stone et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange

(2012) S. Munoz-Galvan et al.   MOLECULAR AND CELLULAR BIOLOGY

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components

(2011) Peter C. Stirling et al.   PLoS Genetics

Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors

(2010) Steven JM Jones et al.   GENOME BIOLOGY

Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis

(2009) B. M. Hall et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Participation of DNA Polymerase   in Replication of Undamaged DNA in Saccharomyces cerevisiae

(2009) M. R. Northam et al.   GENETICS

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

(2009) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

(2008) Scott D McCulloch et al.   CELL RESEARCH

Participation of DNA repair in the response to 5-fluorouracil

(2008) M. D. Wyatt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Estimating the Per-Base-Pair Mutation Rate in the Yeast Saccharomyces cerevisiae

(2008) Gregory I. Lang et al.   GENETICS

Defining genetic interaction

(2008) R. Mani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA