LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels

LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development

(2016) Morgane Boillot et al.   Scientific Reports

Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing

(2015) M. J. Kole et al.   JOURNAL OF NEUROSCIENCE

Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizures

(2014) Morgane Boillot et al.   BRAIN

Analog modulation of spike-evoked transmission in CA3 circuits is determined by axonal Kv1.1 channels in a time-dependent manner

(2014) Andrzej Bialowas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

LGI Proteins in the Nervous System

(2013) Linde Kegel et al.   ASN Neuro

Autoantibodies to Epilepsy-Related LGI1 in Limbic Encephalitis Neutralize LGI1-ADAM22 Interaction and Reduce Synaptic AMPA Receptors

(2013) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

A rat model for LGI1-related epilepsies

(2012) Stéphanie Baulac et al.   HUMAN MOLECULAR GENETICS

LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11

(2012) Koji Sagane et al.   International Journal of Biological Sciences

Epilepsy Gene LGI1 Regulates Postnatal Developmental Remodeling of Retinogeniculate Synapses

(2012) Y.-D. Zhou et al.   JOURNAL OF NEUROSCIENCE

Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice

(2010) Elodie Chabrol et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission

(2010) Tatjana Lalic et al.   EPILEPSIA

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

(2010) Y. Teng et al.   HUMAN MOLECULAR GENETICS

Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability

(2010) Y. Eugene Yu et al.   HUMAN MOLECULAR GENETICS

LGI1 Is a Nogo Receptor 1 Ligand that Antagonizes Myelin-Based Growth Inhibition

(2010) R. Thomas et al.   JOURNAL OF NEUROSCIENCE

ADAM22, A Kv1 Channel-Interacting Protein, Recruits Membrane-Associated Guanylate Kinases to Juxtaparanodes of Myelinated Axons

(2010) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

Spike-Time Precision and Network Synchrony Are Controlled by the Homeostatic Regulation of the D-Type Potassium Current

(2010) R. H. Cudmore et al.   JOURNAL OF NEUROSCIENCE

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

Disruption of LGI1–linked synaptic complex causes abnormal synaptic transmission and epilepsy

(2010) Yuko Fukata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy

(2009) Yu-Dong Zhou et al.   NATURE MEDICINE

Clinical spectrum of voltage-gated potassium channel autoimmunity

(2008) K. M. Tan et al.   NEUROLOGY