Selective regulation of Notch ligands during angiogenesis is mediated by vimentin

Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity

(2017) Vincent C. Luca et al.   SCIENCE

The Notch meeting: an odyssey from structure to function

(2016) Ajay Chitnis et al.   DEVELOPMENT

Keratins Are Going Nuclear

(2016) Ryan P. Hobbs et al.   DEVELOPMENTAL CELL

Defining Single Molecular Forces Required for Notch Activation Using Nano Yoyo

(2016) Farhan Chowdhury et al.   NANO LETTERS

Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling

(2016) Fang Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Intermediate Filaments in Vesicular Traffic

(2016) Azzurra Margiotta et al.   Cells

Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1

(2015) A.-R. Pedrosa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vimentin–ERK Signaling Uncouples Slug Gene Regulatory Function

(2015) Reetta Virtakoivu et al.   CANCER RESEARCH

Keratins in health and disease

(2015) Diana M Toivola et al.   CURRENT OPINION IN CELL BIOLOGY

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

(2015) Z. Liu et al.   DEVELOPMENT

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

(2015) Ryan P Hobbs et al.   NATURE GENETICS

Notch signal strength controls cell fate in the haemogenic endothelium

(2015) Leonor Gama-Norton et al.   Nature Communications

Vimentin regulates activation of the NLRP3 inflammasome

(2015) Gimena dos Santos et al.   Nature Communications

Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers

(2015) Yaming Jiu et al.   Cell Reports

Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca2+ entry in human pulmonary arterial smooth muscle cells

(2014) Hisao Yamamura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Targeting Met and Notch in theLfng-deficient,Met-amplified triple-negative breast cancer

(2014) Shubing Zhang et al.   CANCER BIOLOGY & THERAPY

PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner

(2014) Marika Sjöqvist et al.   CELL RESEARCH

Vimentin as an Integral Regulator of Cell Adhesion and Endothelial Sprouting

(2014) Jui M. Dave et al.   MICROCIRCULATION

NOTCH Decoys That Selectively Block DLL/NOTCH or JAG/NOTCH Disrupt Angiogenesis by Unique Mechanisms to Inhibit Tumor Growth

(2014) Thaned Kangsamaksin et al.   Cancer Discovery

Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

(2014) Lauren LeBon et al.   eLife

Synaptojanin-2 Binding Protein Stabilizes the Notch Ligands DLL1 and DLL4 and Inhibits Sprouting Angiogenesis

(2013) M. Gordian Adam et al.   CIRCULATION RESEARCH

Mechanosensing through focal adhesion-anchored intermediate filaments

(2013) Martin Gregor et al.   FASEB JOURNAL

Proteomic Profiling of Endothelial Invasion Revealed Receptor for Activated C Kinase 1 (RACK1) Complexed with Vimentin to Regulate Focal Adhesion Kinase (FAK)

(2013) Jui M. Dave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsic Selectivity of Notch 1 for Delta-like 4 Over Delta-like 1

(2013) Marie Blanke Andrawes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch signaling at a glance

(2013) K. Hori et al.   JOURNAL OF CELL SCIENCE

Colon cancer progression is driven by APEX1-mediated upregulation of Jagged

(2013) Mi-Hwa Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

High glucose-induced jagged 1 in endothelial cells disturbs notch signaling for angiogenesis: A novel mechanism of diabetic vasculopathy

(2013) Chang-Hwan Yoon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling

(2013) X. Wang et al.   SCIENCE

Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation

(2012) Hyeong-Il Kwak et al.   ANGIOGENESIS

Extrinsic Notch Ligand Delta-Like 1 Regulates Tip Cell Selection and Vascular Branching Morphogenesis

(2012) L.C. Napp et al.   CIRCULATION RESEARCH

Optical Tweezers Studies on Notch: Single-Molecule Interaction Strength Is Independent of Ligand Endocytosis

(2012) Bhupinder Shergill et al.   DEVELOPMENTAL CELL

Notch Ligand Endocytosis Generates Mechanical Pulling Force Dependent on Dynamin, Epsins, and Actin

(2012) Laurence Meloty-Kapella et al.   DEVELOPMENTAL CELL

Notch ligand endocytosis: Mechanistic basis of signaling activity

(2012) Abdiwahab A. Musse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Astrocytes Negatively Regulate Neurogenesis Through the Jagged1-Mediated Notch Pathway

(2012) Ulrika Wilhelmsson et al.   STEM CELLS

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Insights into intermediate filament regulation from development to ageing

(2011) C. L. Hyder et al.   JOURNAL OF CELL SCIENCE

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

(2011) Virginia Guarani et al.   NATURE

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

Control of Notch-ligand endocytosis by ligand-receptor interaction

(2010) E. M. Hansson et al.   JOURNAL OF CELL SCIENCE

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

(2010) K Vuoriluoto et al.   ONCOGENE

Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells

(2010) M. Mazzone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Vimentin Regulates Scribble Activity by Protecting It from Proteasomal Degradation

(2009) Dominic C.Y. Phua et al.   MOLECULAR BIOLOGY OF THE CELL

Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos

(2008) A. Trindade et al.   BLOOD

Jagged-1 and Notch3 Juxtacrine Loop Regulates Ovarian Tumor Growth and Adhesion

(2008) J.-H. Choi et al.   CANCER RESEARCH

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

(2008) Jemima Cordle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

(2008) Sami Kilpinen et al.   GENOME BIOLOGY

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

(2007) Yann Wallez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES