Colon cancer progression is driven by APEX1-mediated upregulation of Jagged

Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer

(2015)   Oncotarget

Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells

(2011) Nilay Sethi et al.   CANCER CELL

Notch3 signalling promotes tumour growth in colorectal cancer

(2011) Valentina Serafin et al.   JOURNAL OF PATHOLOGY

Impact of APE1/Ref-1 Redox Inhibition on Pancreatic Tumor Growth

(2011) M. L. Fishel et al.   MOLECULAR CANCER THERAPEUTICS

Notch signaling: Emerging molecular targets for cancer therapy

(2010) Ling Yin et al.   BIOCHEMICAL PHARMACOLOGY

Notch-1 Inhibition by Withaferin-A: A Therapeutic Target against Colon Carcinogenesis

(2010) S. Koduru et al.   MOLECULAR CANCER THERAPEUTICS

Therapeutic antibody targeting of individual Notch receptors

(2010) Yan Wu et al.   NATURE

The Wnt Target Jagged-1 Mediates the Activation of Notch Signaling by Progastrin in Human Colorectal Cancer Cells

(2009) J. Pannequin et al.   CANCER RESEARCH

Role of Notch signaling in colorectal cancer

(2009) L. Qiao et al.   CARCINOGENESIS

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

NOTCH3 Expression Is Induced in Mural Cells Through an Autoregulatory Loop That Requires Endothelial-Expressed JAGGED1

(2009) Hua Liu et al.   CIRCULATION RESEARCH

Ape1/Ref-1 Induces Glial Cell-Derived Neurotropic Factor (GDNF) Responsiveness by Upregulating GDNF Receptor  1 Expression

(2009) M.-H. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling

(2009) S Guilmeau et al.   ONCOGENE

Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer

(2009) V. Rodilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

(2009) S. Fre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein

(2008) Kishor K. Bhakat et al.   ANTIOXIDANTS & REDOX SIGNALING

The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

(2008) Gianluca Tell et al.   ANTIOXIDANTS & REDOX SIGNALING

Jagged-1 and Notch3 Juxtacrine Loop Regulates Ovarian Tumor Growth and Adhesion

(2008) J.-H. Choi et al.   CANCER RESEARCH

APE1/Ref-1 regulates PTEN expression mediated by Egr-1

(2008) Damiano Fantini et al.   FREE RADICAL RESEARCH

The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: Therapeutic implications in tumor angiogenesis

(2008) Gang-Ming Zou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration

(2008) G.-M. Zou et al.   MOLECULAR CANCER THERAPEUTICS

Notch signaling regulates tumor angiogenesis by diverse mechanisms

(2008) J Dufraine et al.   ONCOGENE

Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth

(2007) Melissa L. Fishel et al.   DNA REPAIR

Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer

(2007) Terumasa Noike et al.   HUMAN PATHOLOGY