ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+T cell pathogenicity during CNS inflammation

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Exposure of phosphatidylserine on the cell surface

(2016) S Nagata et al.   CELL DEATH AND DIFFERENTIATION

LAP: the protector against autoimmunity

(2016) Urmi Bandyopadhyay et al.   CELL RESEARCH

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

(2016) Christian Schläger et al.   NATURE

Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

(2016) Jennifer Martinez et al.   NATURE

Gatekeeper role of brain antigen-presenting CD11c+ cells in neuroinflammation

(2015) M. Paterka et al.   EMBO JOURNAL

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

(2015) Andrew L. Croxford et al.   IMMUNITY

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Oligodendrocyte death results in immune-mediated CNS demyelination

(2015) Maria Traka et al.   NATURE NEUROSCIENCE

Deficiency of Autophagy in Dendritic Cells Protects against Experimental Autoimmune Encephalomyelitis

(2014) Abhisek Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune cell trafficking from the brain maintains CNS immune tolerance

(2014) Mohammad G. Mohammad et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing

(2013) Susana Romao et al.   JOURNAL OF CELL BIOLOGY

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains

(2013) Jimmy L Huynh et al.   NATURE NEUROSCIENCE

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendrocytes and the early multiple sclerosis lesion

(2012) John W. Prineas et al.   ANNALS OF NEUROLOGY

Acquitting an APC: DCs found “not guilty” after trial by ablation

(2012) Burkhard Becher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE

(2012) Magnus Isaksson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

(2012) Nir Yogev et al.   IMMUNITY

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

(2012) Jun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

(2011) Niroshana Anandasabapathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role for MyD88, TLR2 and TLR9 but Not TLR1, TLR4 or TLR6 in Experimental Autoimmune Encephalomyelitis

(2011) S. Miranda-Hernandez et al.   JOURNAL OF IMMUNOLOGY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system

(2010) Carolin Prodinger et al.   ACTA NEUROPATHOLOGICA

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

(2010) Scott B Berger et al.   NATURE IMMUNOLOGY

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

EAE: An immunologist's magic eye

(2009) Gurumoorthy Krishnamoorthy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Localizing central nervous system immune surveillance: Meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

(2008) Pia Kivisäkk et al.   ANNALS OF NEUROLOGY

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling inDrosophila

(2008) Gábor Juhász et al.   JOURNAL OF CELL BIOLOGY

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY