标题
Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 29, Pages E5891-E5899
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-06-29
DOI
10.1073/pnas.1701990114
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phosphorylation of a Tyrosine Residue on Zap70 by Lck and Its Subsequent Binding via an SH2 Domain May Be a Key Gatekeeper of T Cell Receptor SignalingIn Vivo
- (2016) Peter A. Thill et al. MOLECULAR AND CELLULAR BIOLOGY
- Recruitment of calcineurin to the TCR positively regulates T cell activation
- (2016) Debjani Dutta et al. NATURE IMMUNOLOGY
- Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling
- (2016) Jessica Dobbins et al. Science Signaling
- Mitochondrial dysfunction remodels one-carbon metabolism in human cells
- (2016) Xiaoyan Robert Bao et al. eLife
- Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling
- (2016) Jessica Dobbins et al. Science Signaling
- T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity
- (2015) Vaishali R. Moulton et al. JOURNAL OF CLINICAL INVESTIGATION
- The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck
- (2015) Kyung-Ho Roh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid in T-cell receptor transmembrane signaling
- (2015) Wei Wu et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Adoptive cell transfer as personalized immunotherapy for human cancer
- (2015) S. A. Rosenberg et al. SCIENCE
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway
- (2015) Hanna Sjölin-Goodfellow et al. Science Signaling
- The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway
- (2015) Hanna Sjölin-Goodfellow et al. Science Signaling
- Membrane Association of the CD3 Signaling Domain Is Required for Optimal T Cell Development and Function
- (2014) M. L. Bettini et al. JOURNAL OF IMMUNOLOGY
- Insights into the initiation of TCR signaling
- (2014) Arup K Chakraborty et al. NATURE IMMUNOLOGY
- In vitro membrane reconstitution of the T-cell receptor proximal signaling network
- (2014) Enfu Hui et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor
- (2014) Javier Casas et al. Nature Communications
- Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
- (2013) Noah J. Tubo et al. CELL
- Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling
- (2013) Ying Xim Tan et al. NATURE IMMUNOLOGY
- T Cell Activation Results in Conformational Changes in the Src Family Kinase Lck to Induce Its Activation
- (2013) A. Stirnweiss et al. Science Signaling
- TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56lck residues
- (2012) Alice M. Nyakeriga et al. CYTOMETRY PART A
- Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain
- (2012) Etienne Gagnon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Biophysical mechanism of T-cell receptor triggering in a reconstituted system
- (2012) John R. James et al. NATURE
- Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids
- (2012) Xiaoshan Shi et al. NATURE
- How the TCR balances sensitivity and specificity for the recognition of self and pathogens
- (2012) Gerald P Morris et al. NATURE IMMUNOLOGY
- The CD3 Subunit Contains a Phosphoinositide-Binding Motif That Is Required for the Stable Accumulation of TCR-CD3 Complex at the Immunological Synapse
- (2011) L. M. DeFord-Watts et al. JOURNAL OF IMMUNOLOGY
- Basic residues in the T-cell receptor cytoplasmic domain mediate membrane association and modulate signaling
- (2011) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Feedback Circuits Monitor and Adjust Basal Lck-Dependent Events in T Cell Receptor Signaling
- (2011) J. R. Schoenborn et al. Science Signaling
- Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI
- (2010) Patrick G. Hogan et al. Annual Review of Immunology
- CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development
- (2010) Julie Zikherman et al. IMMUNITY
- Constitutively Active Lck Kinase in T Cells Drives Antigen Receptor Signal Transduction
- (2010) Konstantina Nika et al. IMMUNITY
- The structural basis for intramembrane assembly of an activating immunoreceptor complex
- (2010) Matthew E Call et al. NATURE IMMUNOLOGY
- Lck and the nature of the T cell receptor trigger
- (2010) Simon J. Davis et al. TRENDS IN IMMUNOLOGY
- Structural Biology of the T-cell Receptor: Insights into Receptor Assembly, Ligand Recognition, and Initiation of Signaling
- (2010) K. W. Wucherpfennig et al. Cold Spring Harbor Perspectives in Biology
- Organization of proximal signal initiation at the TCR:CD3 complex
- (2009) Clifford S. Guy et al. IMMUNOLOGICAL REVIEWS
- Critical and Multiple Roles for the CD3 Intracytoplasmic Tail in Double Negative to Double Positive Thymocyte Differentiation
- (2009) J.-F. Brodeur et al. JOURNAL OF IMMUNOLOGY
- The Cytoplasmic Tail of the T Cell Receptor CD3 Subunit Contains a Phospholipid-Binding Motif that Regulates T Cell Functions
- (2009) L. M. DeFord-Watts et al. JOURNAL OF IMMUNOLOGY
- Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif
- (2008) Chenqi Xu et al. CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now