Aβ seeds and prions: How close the fit?

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

(2017) Wei Qiang et al.   NATURE

The Exceptional Vulnerability of Humans to Alzheimer’s Disease

(2017) Lary C. Walker et al.   TRENDS IN MOLECULAR MEDICINE

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions

(2016) Rona M. Barron et al.   ACTA NEUROPATHOLOGICA

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

(2016) Bruno Vasconcelos et al.   ACTA NEUROPATHOLOGICA

Dura mater is a potential source of Aβ seeds

(2016) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy

(2016) Tsuyoshi Hamaguchi et al.   ACTA NEUROPATHOLOGICA

Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines

(2016) Jean D. Sipe et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration

(2016) Michel Goedert et al.   BRAIN

Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease

(2016) Zachary M. March et al.   BRAIN RESEARCH

Conversion of Synthetic Aβ to In Vivo Active Seeds and Amyloid Plaque Formation in a Hippocampal Slice Culture Model

(2016) Renata Novotny et al.   JOURNAL OF NEUROSCIENCE

Mammalian prions and their wider relevance in neurodegenerative diseases

(2016) John Collinge   NATURE

Structure of aggregates revealed

(2016) Robert Tycko   NATURE

Prions, amyloids, and RNA: Pieces of a puzzle

(2016) Anton A. Nizhnikov et al.   Prion

Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease

(2016) Mark Cohen et al.   Prion

The Role of Functional Prion-Like Proteins in the Persistence of Memory

(2016) Kausik Si et al.   Cold Spring Harbor Perspectives in Biology

Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration

(2016) James Alibhai et al.   PLOS BIOLOGY

Highly potent intracellular membrane-associated Aβ seeds

(2016) Anne-Marie Marzesco et al.   Scientific Reports

Neurodegenerative Diseases: Expanding the Prion Concept

(2015) Lary C. Walker et al.   Annual Review of Neuroscience

Rapidly progressive Alzheimer’s disease features distinct structures of amyloid-β

(2015) Mark L. Cohen et al.   BRAIN

Progression of Seed-Induced Aβ Deposition within the Limbic Connectome

(2015) Lan Ye et al.   BRAIN PATHOLOGY

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

(2015) Zane Jaunmuktane et al.   NATURE

Persistence of Aβ seeds in APP null mouse brain

(2015) Lan Ye et al.   NATURE NEUROSCIENCE

Amyloid Polymorphism: Structural Basis and Neurobiological Relevance

(2015) Robert Tycko   NEURON

Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?

(2014) Michael Beekes et al.   ACTA NEUROPATHOLOGICA

Aβ seeds resist inactivation by formaldehyde

(2014) Sarah K. Fritschi et al.   ACTA NEUROPATHOLOGICA

Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid

(2014) Sarah K. Fritschi et al.   BRAIN

Multiple Factors Contribute to the Peripheral Induction of Cerebral  -Amyloidosis

(2014) Y. S. Eisele et al.   JOURNAL OF NEUROSCIENCE

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

(2014) Jakob Domert et al.   NEUROBIOLOGY OF DISEASE

Direct Evidence for Self-Propagation of Different Amyloid-β Fibril Conformations

(2014) Thomas Spirig et al.   Neurodegenerative Diseases

Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

(2014) Karin Magnusson et al.   Prion

Distinct synthetic A  prion strains producing different amyloid deposits in bigenic mice

(2014) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serial propagation of distinct strains of A  prions from Alzheimer's disease patients

(2014) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology and Genetics of Prions Causing Neurodegeneration

(2013) Stanley B. Prusiner   Annual Review of Genetics

Amyloids and Yeast Prion Biology

(2013) Reed B. Wickner et al.   BIOCHEMISTRY

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

(2013) Götz Heilbronner et al.   EMBO REPORTS

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Cofactor Molecules Induce Structural Transformation during Infectious Prion Formation

(2013) Michael B. Miller et al.   STRUCTURE

Evaluation of Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone

(2013) David J. Irwin et al.   JAMA Neurology

Spectral Discrimination of Cerebral Amyloid Lesions after Peripheral Application of Luminescent Conjugated Oligothiophenes

(2012) Bettina M. Wegenast-Braun et al.   AMERICAN JOURNAL OF PATHOLOGY

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid

(2012) S. Nath et al.   JOURNAL OF NEUROSCIENCE

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Purified and synthetic Alzheimer's amyloid beta (A ) prions

(2012) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain

(2011) Tsuyoshi Hamaguchi et al.   ACTA NEUROPATHOLOGICA

Seed and grow: a two-step model for nuclear body biogenesis: Figure 1.

(2011) Miroslav Dundr   JOURNAL OF CELL BIOLOGY

Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats

(2011) Rebecca F. Rosen et al.   JOURNAL OF NEUROCHEMISTRY

Soluble A  Seeds Are Potent Inducers of Cerebral  -Amyloid Deposition

(2011) F. Langer et al.   JOURNAL OF NEUROSCIENCE

De novo induction of amyloid-β deposition in vivo

(2011) R Morales et al.   MOLECULAR PSYCHIATRY

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

(2011) Malin K. Sandberg et al.   NATURE

The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ

(2011) Ola Philipson et al.   NEUROBIOLOGY OF AGING

Mapping the Road Forward in Alzheimer's Disease

(2011) D. M. Holtzman et al.   Science Translational Medicine

Peripherally Applied A -Containing Inoculates Induce Cerebral  -Amyloidosis

(2010) Y. S. Eisele et al.   SCIENCE

Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer’s disease

(2009) Rebecca F. Rosen et al.   ACTA NEUROPATHOLOGICA

Small organic probes as amyloid specific ligands - Past and recent molecular scaffolds

(2009) K. Peter R. Nilsson   FEBS LETTERS

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE