Cholesterol esterification inhibition and imatinib treatment synergistically inhibit growth of BCR-ABL mutation-independent resistant chronic myelogenous leukemia

Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

(2016) J Li et al.   ONCOGENE

Avasimibe Encapsulated in Human Serum Albumin Blocks Cholesterol Esterification for Selective Cancer Treatment

(2015) Steve Seung-Young Lee et al.   ACS Nano

Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations

(2014) E. Traer et al.   BLOOD

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

(2014) Shuhua Yue et al.   Cell Metabolism

A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia

(2014) L. Ma et al.   Science Translational Medicine

Direct Visualization of De novo Lipogenesis in Single Living Cells

(2014) Junjie Li et al.   Scientific Reports

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

Imatinib discontinuation in chronic phase myeloid leukaemia patients in sustained complete molecular response: A randomised trial of the Dutch–Belgian Cooperative Trial for Haemato-Oncology (HOVON)

(2013) Noortje Thielen et al.   EUROPEAN JOURNAL OF CANCER

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Lipid metabolism in cancer

(2012) Claudio R. Santos et al.   FEBS Journal

Cholesterol esters as growth regulators of lymphocytic leukaemia cells

(2011) M. F. Mulas et al.   CELL PROLIFERATION

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

Mechanisms of acquired resistance to tyrosine kinase inhibitors

(2011) Yi-fan Chen et al.   Acta Pharmaceutica Sinica B

Acyl-coenzyme A: Cholesterol acyltransferase inhibitor Avasimibe affect survival and proliferation of glioma tumor cell lines

(2010) Sana Bemlih et al.   CANCER BIOLOGY & THERAPY

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation

(2009) Caryl J. Antalis et al.   BREAST CANCER RESEARCH AND TREATMENT

Management of chronic myeloid leukaemia in clinical practice in France: results of the French subset of patients from the UNIC study

(2009) Mauricette Michallet et al.   CURRENT MEDICAL RESEARCH AND OPINION

High-Speed Vibrational Imaging and Spectral Analysis of Lipid Bodies by Compound Raman Microscopy

(2009) Mikhail N. Slipchenko et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia

(2009) A Hochhaus et al.   LEUKEMIA

A BCR-ABL Mutant Lacking Direct Binding Sites for the GRB2, CBL and CRKL Adapter Proteins Fails to Induce Leukemia in Mice

(2009) Kara J. Johnson et al.   PLoS One