Solving Blue Light Riddles: New Lessons from Flavin-binding LOV Photoreceptors

Light-Mediated Hormonal Regulation of Plant Growth and Development

(2016) Mieke de Wit et al.   Annual Review of Plant Biology

Blue-Light Inhibition of Listeria monocytogenes Growth Is Mediated by Reactive Oxygen Species and Is Influenced by σBand the Blue-Light Sensor Lmo0799

(2016) Beth O'Donoghue et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Photochemical Reactions of the LOV and LOV-Linker Domains of the Blue Light Sensor Protein YtvA

(2016) Seokwoo Choi et al.   BIOCHEMISTRY

Light signaling and plant responses to blue and UV radiations—Perspectives for applications in horticulture

(2016) Lydie Huché-Thélier et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

A Native Threonine Coordinates Ordered Water to Tune Light-Oxygen-Voltage (LOV) Domain Photocycle Kinetics and Osmotic Stress Signaling inTrichoderma reeseiENVOY

(2016) Jameela Lokhandwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain

(2016) Jimena Rinaldi et al.   JOURNAL OF MOLECULAR BIOLOGY

Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy

(2016) Katrin Röllen et al.   JOURNAL OF MOLECULAR BIOLOGY

Photoreceptors mapping from past history till date

(2016) Parul Parihar et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Photophysics of the LOV-Based Fluorescent Protein Variant iLOV-Q489K Determined by Simulation and Experiment

(2016) Mehdi D. Davari et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Evolutionary aspects of plant photoreceptors

(2016) Fay-Wei Li et al.   JOURNAL OF PLANT RESEARCH

Diverse photoreceptors and light responses in plants

(2016) Sam-Geun Kong et al.   JOURNAL OF PLANT RESEARCH

Molecular mechanism of phototropin light signaling

(2016) Koji Okajima   JOURNAL OF PLANT RESEARCH

Blue light-mediated transcriptional activation and repression of gene expression in bacteria

(2016) Premkumar Jayaraman et al.   NUCLEIC ACIDS RESEARCH

Selective Photoreceptor Gene Knock-out Reveals a Regulatory Role for the Growth Behavior ofPseudomonas syringae

(2016) Rashmi Shah et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Functional and topological diversity of LOV domain photoreceptors

(2016) Spencer T. Glantz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a Native-like Aureochrome 1a LOV Domain Dimer from Phaeodactylum tricornutum

(2016) Ankan Banerjee et al.   STRUCTURE

Library-Aided Probing of Linker Determinants in Hybrid Photoreceptors

(2016) Robert Ohlendorf et al.   ACS Synthetic Biology

Blue light-induced LOV domain dimerization enhances the affinity of Aureochrome 1a for its target DNA sequence

(2016) Udo Heintz et al.   eLife

Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains

(2016) Anthony M. Buckley et al.   Scientific Reports

Natural Photoreceptors as a Source of Fluorescent Proteins, Biosensors, and Optogenetic Tools

(2015) Daria M. Shcherbakova et al.   Annual Review of Biochemistry

Ligand-Induced Folding of a Two-Component Signaling Receiver Domain

(2015) Victor J. Ocasio et al.   BIOCHEMISTRY

Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae

(2015) Stephan Endres et al.   BMC MICROBIOLOGY

LOV-based reporters for fluorescence imaging

(2015) Anthony M Buckley et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Seeing the world differently: variability in the photosensory mechanisms of two model fungi

(2015) Arko Dasgupta et al.   ENVIRONMENTAL MICROBIOLOGY

Photoactivation of the cryptochrome/photolyase superfamily

(2015) Jing Wang et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS

Direct 765 nm Optical Excitation of Molecular Oxygen in Solution and in Single Mammalian Cells

(2015) Mikkel Bregnhøj et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Theoretical Characterization of the Flavin-Based Fluorescent Protein iLOV and its Q489K Mutant

(2015) Maria G. Khrenova et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Rational Design of an Efficient, Genetically Encodable, Protein-Encased Singlet Oxygen Photosensitizer

(2015) Michael Westberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

LOV is all we need

(2015) Robert Grosse   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional characterization of Ostreococcus tauri phototropin

(2015) Stuart Sullivan et al.   NEW PHYTOLOGIST

Singlet oxygen photosensitisation by the fluorescent protein Pp2FbFP L30M, a novel derivative of Pseudomonas putida flavin-binding Pp2FbFP

(2015) Joaquim Torra et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

A search for radical intermediates in the photocycle of LOV domains

(2015) Roger Jan Kutta et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Functional Characterization of a LOV-Histidine Kinase Photoreceptor fromXanthomonas citrisubsp.citri

(2015) Ivana Kraiselburd et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

The Evolution and Functional Role of Flavin-based Prokaryotic Photoreceptors

(2015) Aba Losi et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Short LOV Proteins in Methylocystis Reveal Insight into LOV Domain Photocycle Mechanisms

(2015) Kaley K. El-Arab et al.   PLoS One

A critical element of the light-induced quaternary structural changes in YtvA-LOV

(2015) Rang Lee et al.   PROTEIN SCIENCE

Structural Biochemistry of a Fungal LOV Domain Photoreceptor Reveals an Evolutionarily Conserved Pathway Integrating Light and Oxidative Stress

(2015) Jameela Lokhandwala et al.   STRUCTURE

The general stress response in Alphaproteobacteria

(2015) Anne Francez-Charlot et al.   TRENDS IN MICROBIOLOGY

Visualizing the relevance of bacterial blue- and red-light receptors during plant-pathogen interaction

(2015) Ada Ricci et al.   Environmental Microbiology Reports

Signal transduction in light–oxygen–voltage receptors lacking the adduct-forming cysteine residue

(2015) Estella F. Yee et al.   Nature Communications

Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity

(2015) Arko Dasgupta et al.   PLoS Genetics

Evolutionary History of the Photolyase/Cryptochrome Superfamily in Eukaryotes

(2015) Qiming Mei et al.   PLoS One

Molecular Dynamics Simulation of Dioxygen Pathways through Mini Singlet Oxygen Generator (miniSOG), a Genetically Encoded Marker and Killer Protein

(2014) Francesco Pietra   CHEMISTRY & BIODIVERSITY

A cyanobacterial light activated adenylyl cyclase partially restores development of a Dictyostelium discoideum, adenylyl cyclase a null mutant

(2014) Zhi-hui Chen et al.   JOURNAL OF BIOTECHNOLOGY

TheBrucella abortusvirulence regulator, LovhK, is a sensor kinase in the general stress response signalling pathway

(2014) Hye-Sook Kim et al.   MOLECULAR MICROBIOLOGY

Plant Flavoprotein Photoreceptors

(2014) J. M. Christie et al.   PLANT AND CELL PHYSIOLOGY

Factors That Control the Chemistry of the LOV Domain Photocycle

(2014) Josiah P. Zayner et al.   PLoS One

The Dark Recovery Rate in the Photocycle of the Bacterial Photoreceptor YtvA Is Affected by the Cellular Environment and by Hydration

(2014) Francesca Pennacchietti et al.   PLoS One

Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation

(2014) Giomar Rivera-Cancel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysical, Mutational, and Functional Investigation of the Chromophore-Binding Pocket of Light-Oxygen-Voltage Photoreceptors

(2014) Ralph P. Diensthuber et al.   ACS Synthetic Biology

The blue-light receptor YtvA from Bacillus subtilis is permanently incorporated into the stressosome independent of the illumination state

(2013) Marcel Jurk et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A LOV-domain-mediated blue-light-activated adenylate (adenylyl) cyclase from the cyanobacteriumMicrocoleus chthonoplastesPCC 7420

(2013) Sarah Raffelberg et al.   BIOCHEMICAL JOURNAL

Optobiology: optical control of biological processes via protein engineering

(2013) Benjamin Kim et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Primary Photochemistry of the Dark- and Light-Adapted States of the YtvA Protein from Bacillus subtilis

(2013) Sang-Hun Song et al.   BIOCHEMISTRY

Blue Light-Induced Dimerization of a Bacterial LOV–HTH DNA-Binding Protein

(2013) Brian D. Zoltowski et al.   BIOCHEMISTRY

Zeitlupe Senses Blue-Light Fluence To Mediate Circadian Timing in Arabidopsis thaliana

(2013) Ashutosh Pudasaini et al.   BIOCHEMISTRY

Blue Light Regulated Two-Component Systems: Enzymatic and Functional Analyses of Light-Oxygen-Voltage (LOV)-Histidine Kinases and Downstream Response Regulators

(2013) Fernando Correa et al.   BIOCHEMISTRY

The amino acids surrounding the flavin 7a-methyl group determine the UVA spectral features of a LOV protein

(2013) Sarah Raffelberg et al.   BIOLOGICAL CHEMISTRY

Photophysics of Structurally Modified Flavin Derivatives in the Blue-Light Photoreceptor YtvA: A Combined Experimental and Theoretical Study

(2013) Mario R. Silva-Junior et al.   CHEMBIOCHEM

Light regulates motility, attachment and virulence in the plant pathogenPseudomonas syringaepv tomato DC3000

(2013) Isabel Río-Álvarez et al.   ENVIRONMENTAL MICROBIOLOGY

Singlet Oxygen Generation by the Genetically Encoded Tag miniSOG

(2013) Rubén Ruiz-González et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modeling the functioning of YtvA in the general stress response in Bacillus subtilis

(2013) Jeroen B. van der Steen et al.   Molecular BioSystems

Cycles of light and dark co-ordinate reversible colony differentiation inListeria monocytogenes

(2013) Teresa Tiensuu et al.   MOLECULAR MICROBIOLOGY

A ternary AppA–PpsR–DNA complex mediates light regulation of photosynthesis-related gene expression

(2013) Andreas Winkler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distance-tree analysis, distribution and co-presence of bilin- and flavin-binding prokaryotic photoreceptors for visible light

(2013) Carmen Mandalari et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Signaling mechanisms of LOV domains: new insights from molecular dynamics studies

(2013) Peter L. Freddolino et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Membrane development in purple photosynthetic bacteria in response to alterations in light intensity and oxygen tension

(2013) Robert A. Niederman   PHOTOSYNTHESIS RESEARCH

The LOV Protein of Xanthomonas citri subsp. citri Plays a Significant Role in the Counteraction of Plant Immune Responses during Citrus Canker

(2013) Ivana Kraiselburd et al.   PLoS One

Full-Length Structure of a Sensor Histidine Kinase Pinpoints Coaxial Coiled Coils as Signal Transducers and Modulators

(2013) Ralph P. Diensthuber et al.   STRUCTURE

Redox and Light Control the Heme-Sensing Activity of AppA

(2013) L. Yin et al.   mBio

Light Regulation of Swarming Motility in Pseudomonas syringae Integrates Signaling Pathways Mediated by a Bacteriophytochrome and a LOV Protein

(2013) L. Wu et al.   mBio

Evolution of Two-Component Signal Transduction Systems

(2012) Emily J. Capra et al.   Annual Review of Microbiology

The Evolution of Flavin-Binding Photoreceptors: An Ancient Chromophore Serving Trendy Blue-Light Sensors

(2012) Aba Losi et al.   Annual Review of Plant Biology

Identification of Natural and Artificial DNA Substrates for Light-Activated LOV–HTH Transcription Factor EL222

(2012) Giomar Rivera-Cancel et al.   BIOCHEMISTRY

Light-Induced Subunit Dissociation by a Light–Oxygen–Voltage Domain Photoreceptor from Rhodobacter sphaeroides

(2012) Karen S. Conrad et al.   BIOCHEMISTRY

Optogenetic control of cell function using engineered photoreceptors

(2012) Gopal P. Pathak et al.   BIOLOGY OF THE CELL

You’ve come a long way: c-di-GMP signaling

(2012) Holger Sondermann et al.   CURRENT OPINION IN MICROBIOLOGY

Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond?

(2012) Tianhong Dai et al.   DRUG RESISTANCE UPDATES

The LovK-LovR Two-Component System Is a Regulator of the General Stress Pathway in Caulobacter crescentus

(2012) R. Foreman et al.   JOURNAL OF BACTERIOLOGY

LOV Domain-Containing F-Box Proteins: Light-Dependent Protein Degradation Modules in Arabidopsis

(2012) Shogo Ito et al.   Molecular Plant

A photochromic bacterial photoreceptor with potential for super-resolution microscopy

(2012) Aba Losi et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

A LOV Protein Modulates the Physiological Attributes of Xanthomonas axonopodis pv. citri Relevant for Host Plant Colonization

(2012) Ivana Kraiselburd et al.   PLoS One

Light regulates attachment, exopolysaccharide production, and nodulation inRhizobium leguminosarumthrough a LOV-histidine kinase photoreceptor

(2012) Hernán R. Bonomi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulating LOV Domain Photodynamics with a Residue Alteration outside the Chromophore Binding Site

(2011) Sang-Hun Song et al.   BIOCHEMISTRY

Modulation of the Photocycle of a LOV Domain Photoreceptor by the Hydrogen-Bonding Network

(2011) Sarah Raffelberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of a short light, oxygen, voltage (LOV) domain protein in blue light- and singlet oxygen-dependent gene regulation in Rhodobacter sphaeroides

(2011) S. Metz et al.   MICROBIOLOGY-SGM

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Function, structure and mechanism of bacterial photosensory LOV proteins

(2011) Julien Herrou et al.   NATURE REVIEWS MICROBIOLOGY

Indication for a Radical Intermediate Preceding the Signaling State in the LOV Domain Photocycle†

(2011) Christian Bauer et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Old Chromophores, New Photoactivation Paradigms, Trendy Applications: Flavins in Blue Light-Sensing Photoreceptors†

(2011) Aba Losi et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Metagenome-based Screening Reveals Worldwide Distribution of LOV-Domain Proteins

(2011) Gopal P. Pathak et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Blue and Red Light Modulates SigB-Dependent Gene Transcription, Swimming Motility and Invasiveness in Listeria monocytogenes

(2011) Nicolai Ondrusch et al.   PLoS One

Structural basis of photosensitivity in a bacterial light-oxygen-voltage/helix-turn-helix (LOV-HTH) DNA-binding protein

(2011) A. I. Nash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Illuminating the early signaling pathway of a fungal light-oxygen-voltage photoreceptor

(2011) Emanuel Peter et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms

(2011) Xiaokun Shu et al.   PLOS BIOLOGY

Ligand-Binding PAS Domains in a Genomic, Cellular, and Structural Context

(2010) Jonathan T. Henry et al.   Annual Review of Microbiology

An Analysis of the Solution Structure and Signaling Mechanism of LovK, a Sensor Histidine Kinase Integrating Light and Redox Signals

(2010) Erin B. Purcell et al.   BIOCHEMISTRY

Excited flavin and pterin coenzyme molecules in evolution

(2010) M. S. Kritsky et al.   BIOCHEMISTRY-MOSCOW

Searching for a photocycle of the cryptochrome photoreceptors

(2010) Bin Liu et al.   CURRENT OPINION IN PLANT BIOLOGY

On the midpoint potential of the FAD chromophore in a BLUF-domain containing photoreceptor protein

(2010) Jos C. Arents et al.   FEBS LETTERS

The PpaA/AerR Regulators of Photosynthesis Gene Expression from Anoxygenic Phototrophic Proteobacteria Contain Heme-Binding SCHIC Domains

(2010) O. V. Moskvin et al.   JOURNAL OF BACTERIOLOGY

FMN Binding and Photochemical Properties of Plant Putative Photoreceptors Containing Two LOV Domains, LOV/LOV Proteins

(2010) Masahiro Kasahara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Switch that Does Not Flip: The Blue-Light Receptor YtvA from Bacillus subtilis Adopts an Elongated Dimer Conformation Independent of the Activation State as Revealed by a Combined AUC and SAXS Study

(2010) Marcel Jurk et al.   JOURNAL OF MOLECULAR BIOLOGY

Engineered photoreceptors as novel optogenetic tools

(2010) Andreas Möglich et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora

(2010) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Key Amino Acids in the Photoactivation Pathway of theSynechocystisSlr1694 BLUF Domain

(2009) Cosimo Bonetti et al.   BIOCHEMISTRY

Novel blue light-sensitive proteins from a metagenomic approach

(2009) G. P. Pathak et al.   ENVIRONMENTAL MICROBIOLOGY

In Vivo Sensitivity of Blue-Light-Dependent Signaling Mediated by AppA/PpsR or PrrB/PrrA in Rhodobacter sphaeroides

(2009) S. Metz et al.   JOURNAL OF BACTERIOLOGY

Distribution and Phylogeny of Light-Oxygen-Voltage-Blue-Light-Signaling Proteins in the Three Kingdoms of Life

(2009) U. Krauss et al.   JOURNAL OF BACTERIOLOGY

In VivoMutational Analysis of YtvA fromBacillus subtilis

(2009) Marcela Avila-Pérez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Illuminating Solution Responses of a LOV Domain Protein with Photocoupled Small-Angle X-Ray Scattering

(2009) Jessica S. Lamb et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanism-based tuning of a LOV domain photoreceptor

(2009) Brian D Zoltowski et al.   Nature Chemical Biology

Interdomain signalling in the blue-light sensing and GTP-binding protein YtvA: A mutagenesis study uncovering the importance of specific protein sites

(2009) Yifen Tang et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Domain Swapping to Assess the Mechanistic Basis of Arabidopsis Phototropin 1 Receptor Kinase Activation and Endocytosis by Blue Light

(2009) E. Kaiserli et al.   PLANT CELL

A Conserved Glutamine Plays a Central Role in LOV Domain Signal Transmission and Its Duration†

(2008) Abigail I. Nash et al.   BIOCHEMISTRY

Light Activation of the LOV Protein Vivid Generates a Rapidly Exchanging Dimer†‡

(2008) Brian D. Zoltowski et al.   BIOCHEMISTRY

The photophysics of flavins: What makes the difference between gas phase and aqueous solution?

(2008) Susanne Salzmann et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

A Blue Light Inducible Two-Component Signal Transduction System in the Plant Pathogen Pseudomonas syringae pv. tomato

(2007) Z. Cao et al.   BIOPHYSICAL JOURNAL