Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading
出版年份 2017 全文链接
标题
Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading
作者
关键词
drug loading, EV therapeutics, exosomes, extracellular vesicles, microvesicles
出版物
PHARMACEUTICAL RESEARCH
Volume 34, Issue 5, Pages 1053-1066
出版商
Springer Nature
发表日期
2017-03-17
DOI
10.1007/s11095-017-2123-5
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- RNAi delivery by exosome-mimetic nanovesicles – Implications for targeting c-Myc in cancer
- (2016) Taral R. Lunavat et al. BIOMATERIALS
- DNA in serum extracellular vesicles is stable under different storage conditions
- (2016) Yang Jin et al. BMC CANCER
- Bovine milk-derived exosomes for drug delivery
- (2016) Radha Munagala et al. CANCER LETTERS
- Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington’s Disease: Background and Evaluation in Cell Culture
- (2016) Xuan Zhang et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes
- (2016) Kasper Bendix Johnsen et al. CYTOTECHNOLOGY
- Exosome-associated AAV vector as a robust and convenient neuroscience tool
- (2016) E Hudry et al. GENE THERAPY
- A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism
- (2016) Xi Lan et al. HEPATOLOGY
- Exosomes Secreted by Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Repair Critical-Sized Bone Defects through Enhanced Angiogenesis and Osteogenesis in Osteoporotic Rats
- (2016) Xin Qi et al. International Journal of Biological Sciences
- Comparing exosome-like vesicles with liposomes for the functional cellular delivery of small RNAs
- (2016) Stephan Stremersch et al. JOURNAL OF CONTROLLED RELEASE
- Good things come in small packages: Overcoming challenges to harness extracellular vesicles for therapeutic delivery
- (2016) Dominique Ingato et al. JOURNAL OF CONTROLLED RELEASE
- Therapeutic and diagnostic applications of extracellular vesicles
- (2016) Stephan Stremersch et al. JOURNAL OF CONTROLLED RELEASE
- Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis
- (2016) Bo Wang et al. MOLECULAR THERAPY
- Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells
- (2016) Myung Soo Kim et al. Nanomedicine-Nanotechnology Biology and Medicine
- Toxicity and inflammatory response in Swiss albino mice after intraperitoneal and oral administration of polyurethane nanoparticles
- (2016) Adny H. Silva et al. TOXICOLOGY LETTERS
- EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
- (2016) Lingling Jiang et al. Nature Communications
- Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
- (2016) Nambin Yim et al. Nature Communications
- Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems
- (2016) Mei-Ju Su et al. Scientific Reports
- Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components
- (2016) Jing Li et al. PLoS One
- In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior
- (2015) Anoek Zomer et al. CELL
- Exosomes as drug delivery vehicles for Parkinson's disease therapy
- (2015) Matthew J. Haney et al. JOURNAL OF CONTROLLED RELEASE
- Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins
- (2015) Gregor Fuhrmann et al. JOURNAL OF CONTROLLED RELEASE
- Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
- (2015) Guohua Lou et al. Journal of Hematology & Oncology
- Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery
- (2015) Tek N. Lamichhane et al. MOLECULAR PHARMACEUTICS
- Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications
- (2015) Sweta Rani et al. MOLECULAR THERAPY
- Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions
- (2015) Carmen Schwechheimer et al. NATURE REVIEWS MICROBIOLOGY
- Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio
- (2015) Tianzhi Yang et al. PHARMACEUTICAL RESEARCH
- Gram-negative and Gram-positive bacterial extracellular vesicles
- (2015) Ji Hyun Kim et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse
- (2015) Yuchen Liu et al. Scientific Reports
- Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice
- (2015) Guo-wen Hu et al. Stem Cell Research & Therapy
- Cell or Cell Membrane-Based Drug Delivery Systems
- (2015) Songwei Tan et al. Theranostics
- Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
- (2015) Kirsten Ridder et al. OncoImmunology
- Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration
- (2014) Keisuke Shimbo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo
- (2014) Bence György et al. BIOMATERIALS
- Exosomes and other extracellular vesicles in host-pathogen interactions
- (2014) J. S. Schorey et al. EMBO REPORTS
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
- (2014) Luisa Pascucci et al. JOURNAL OF CONTROLLED RELEASE
- Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles
- (2014) Zoltán Giricz et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Could bioengineered exosome-mimetic nanovesicles be an efficient strategy for the delivery of chemotherapeutics?
- (2014) Su Chul Jang et al. Nanomedicine
- Inhibition of porcine reproductive and respiratory syndrome virus infection by recombinant adenovirus- and/or exosome-delivered the artificial microRNAs targeting sialoadhesin and CD163 receptors
- (2014) Li Zhu et al. Virology Journal
- Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors
- (2013) Su Chul Jang et al. ACS Nano
- Maximizing exosome colloidal stability following electroporation
- (2013) Joshua L. Hood et al. ANALYTICAL BIOCHEMISTRY
- A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
- (2013) Yanhua Tian et al. BIOMATERIALS
- Exosomes are natural carriers of exogenous siRNA to human cells in vitro
- (2013) Tatyana A Shtam et al. Cell Communication and Signaling
- Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles
- (2013) Sander A.A. Kooijmans et al. JOURNAL OF CONTROLLED RELEASE
- Immunization with Escherichia coli Outer Membrane Vesicles Protects Bacteria-Induced Lethality via Th1 and Th17 Cell Responses
- (2013) O. Y. Kim et al. JOURNAL OF IMMUNOLOGY
- Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis
- (2013) Songwen Ju et al. MOLECULAR THERAPY
- Solid lipid nanoparticles induced hematological changes and inflammatory response in mice
- (2013) Adny Henrique Silva et al. Nanotoxicology
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cells
- (2013) Jin Cai et al. Journal of Molecular Cell Biology
- Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
- (2013) Carolina Villarroya-Beltri et al. Nature Communications
- Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity
- (2013) Jessian L Munoz et al. Molecular Therapy-Nucleic Acids
- Microvesicle-associated AAV Vector as a Novel Gene Delivery System
- (2012) Casey A Maguire et al. MOLECULAR THERAPY
- Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth
- (2012) Arda Mizrak et al. MOLECULAR THERAPY
- Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
- (2012) Shin-ichiro Ohno et al. MOLECULAR THERAPY
- Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes
- (2012) Jessica Wahlgren et al. NUCLEIC ACIDS RESEARCH
- AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness
- (2012) J. Bennett et al. Science Translational Medicine
- Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
- (2012) Hina Kalra et al. PLOS BIOLOGY
- miR-1289 and “Zipcode”-like Sequence Enrich mRNAs in Microvesicles
- (2012) Mehmet Fatih Bolukbasi et al. Molecular Therapy-Nucleic Acids
- Microvesicles: Messengers and mediators of tumor progression
- (2011) Khalid Al-Nedawi et al. CELL CYCLE
- Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain
- (2011) Xiaoying Zhuang et al. MOLECULAR THERAPY
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- ExoCarta 2012: database of exosomal proteins, RNA and lipids
- (2011) S. Mathivanan et al. NUCLEIC ACIDS RESEARCH
- Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles
- (2010) Adam Kulp et al. Annual Review of Microbiology
- Role of anti-oncomirs miR-143 and -145 in human colorectal tumors
- (2010) Y Akao et al. CANCER GENE THERAPY
- Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
- (2010) Nobuyoshi Kosaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Phase I Study of Aromatic L-Amino Acid Decarboxylase Gene Therapy for Parkinson's Disease
- (2010) Shin-ichi Muramatsu et al. MOLECULAR THERAPY
- A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes
- (2010) Dongmei Sun et al. MOLECULAR THERAPY
- Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages
- (2010) Yukihiro Akao et al. MOLECULAR THERAPY
- Functional delivery of viral miRNAs via exosomes
- (2010) D. M. Pegtel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Exosomes are an effective vaccine against congenital toxoplasmosis in mice
- (2009) Céline Beauvillain et al. VACCINE
- Integration Site Selection by Retroviral Vectors: Molecular Mechanism and Clinical Consequences
- (2008) René Daniel et al. HUMAN GENE THERAPY
- Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool
- (2008) J. García-Castro et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Detection of microRNA Expression in Human Peripheral Blood Microvesicles
- (2008) Melissa Piper Hunter et al. PLoS One
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
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