Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using Selectfluor™ (F-TEDA-BF4)

Iron-catalyzed domino indole fluorination/allenic aza-Claisen rearrangement

(2016) Benito Alcaide et al.   CHEMICAL COMMUNICATIONS

Silver-initiated radical ring expansion/fluorination of ethynyl cyclobutanols: efficient synthesis of monofluoroethenyl cyclopentanones

(2016) Qingshan Tian et al.   GREEN CHEMISTRY

Fluorination methods in drug discovery

(2016) Damian E. Yerien et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Lewis Acid Catalyzed Cyclization of Propargylic Alcohols with 2-Vinylphenol

(2016) Ya-Ping Han et al.   ORGANIC LETTERS

BF3·OEt2-AgSCF3 Mediated Trifluoromethylthiolation/Cascade Cyclization of Propynols: Synthesis of 4-((Trifluoromethyl)thio)-2H-chromene and 4-((Trifluoromethyl)thio)-1,2-dihydroquinoline Derivatives

(2016) Yi-Feng Qiu et al.   ORGANIC LETTERS

Synthesis of α-Fluoroketones from Vinyl Azides and Mechanism Interrogation

(2016) Shu-Wei Wu et al.   ORGANIC LETTERS

Synthesis of Substituted Furan/Pyrrole-3-carboxamides through a Tandem Nucleopalladation and Isocyanate Insertion

(2016) Manda Rajesh et al.   ORGANIC LETTERS

Lewis Acid Catalyzed [4 + 3] Cycloaddition of Propargylic Alcohols with Azides

(2016) Ya-Ping Han et al.   ORGANIC LETTERS

Assembly of Fluorinated Quaternary Stereogenic Centers through Catalytic Enantioselective Detrifluoroacetylative Aldol Reactions

(2015) Chen Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A rapid and selective synthesis of α,α-fluorohalo esters via fluorohalogenative or difluorinative hydration of ynol ethers

(2015) Liang Hu et al.   CHEMICAL COMMUNICATIONS

Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators

(2015) Min Guo et al.   CHEMICAL COMMUNICATIONS

Monofluorination of Organic Compounds: 10 Years of Innovation

(2015) Pier Alexandre Champagne et al.   CHEMICAL REVIEWS

Copper/Selectfluor-System-Catalyzed Dehydration-Oxidation of Tertiary Cyclo­alcohols: Access to β-Substituted Cyclohex-2-enones, 4-Arylcoumarins, and Bi­aryls

(2015) Shaobo Ren et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

New fluorinated fructose analogs as selective probes of the hexose transporter protein GLUT5

(2015) Olivier-Mohamad Soueidan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Iron- or silver-catalyzed oxidative fluorination of cyclopropanols for the synthesis of β-fluoroketones

(2015) Shichao Ren et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Mild and metal-free oxy- and amino-fluorination for the synthesis of fluorinated heterocycles

(2014) Dixit Parmar et al.   CHEMICAL COMMUNICATIONS

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Exploration of fluorination reagents starting from FITS reagents

(2014) Teruo Umemoto   JOURNAL OF FLUORINE CHEMISTRY

Hypervalent Iodine-Promoted α-Fluorination of Acetophenone Derivatives with a Triethylamine·HF Complex

(2014) Tsugio Kitamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Nucleophile-Catalyzed Synthesis of Tertiary Alkyl Fluorides via the α-Fluorination of Ketenes: Synthetic and Mechanistic Studies

(2014) Sarah Yunmi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An In Situ Directing Group Strategy for Chiral Anion Phase-Transfer Fluorination of Allylic Alcohols

(2014) Weiwei Zi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Tertiary Alkyl Fluorides: Negishi Cross-Couplings of Racemic α,α-Dihaloketones

(2014) Yufan Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iodo Meyer–Schuster Rearrangement of 3-Alkoxy-2-yn-1-ols for β-Mono (Exclusively Z-Selective)-/Disubstituted α-Iodo-α,β-Unsaturated Esters

(2014) Surendra Puri et al.   ORGANIC LETTERS

Lewis Acid Catalyzed Cascade Reaction of 3-(2-Benzenesulfonamide)propargylic Alcohols to Spiro[indene-benzosultam]s

(2014) Lang Sun et al.   ORGANIC LETTERS

Metal-Free, Efficient Oxyfluorination of Olefins for the Synthesis of α-Fluoroketones

(2014) Qiang Yang et al.   ORGANIC LETTERS

Direct Access to α-Trifluoromethyl Enones via Efficient Copper-Catalyzed Trifluoromethylation of Meyer–Schuster Rearrangement

(2014) Ya-Ping Xiong et al.   ORGANIC LETTERS

Review of recent advances in nucleophilic C–F bond-forming reactions at sp3 centers

(2014) Jimmy Wu   TETRAHEDRON LETTERS

Catalytic fluorination of unactivated C(sp3)–H bonds

(2014) Jun-An Ma et al.   Organic Chemistry Frontiers

Catalytic Enantioselective Difluoroalkylation of Aldehydes

(2013) Peng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Construction of 3-Hydroxy Oxindoles through a Decarboxylative Aldol Addition of Trifluoromethyl α-Fluorinatedgem-Diols toN-Benzyl Isatins

(2013) Ibrayim Saidalimu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and evaluation of 3-deoxy and 3-deoxy-3-fluoro derivatives of gluco- and manno-configured tetrahydropyridoimidazole glycosidase inhibitors

(2013) Cécile Ouairy et al.   CARBOHYDRATE RESEARCH

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Evaluation of Difluoromethyl Ketones as Agonists of the γ-Aminobutyric Acid Type B (GABAB) Receptor

(2013) Changho Han et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Enantiopure Fluorohydrins Using Alcohol Dehydrogenases at High Substrate Concentrations

(2013) Wioleta Borzęcka et al.   JOURNAL OF ORGANIC CHEMISTRY

A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging

(2013) Mickael Huiban et al.   Nature Chemistry

Regioselective Rapid Synthesis of Fully Substituted 1,2,3-Triazoles Mediated by Propargyl Cations

(2013) Huan Zhang et al.   ORGANIC LETTERS

Chiral 1,1-diaryl compounds as important pharmacophores

(2013) Dana Ameen et al.   MedChemComm

Rhodium-Catalyzed Enantioselective Nucleophilic Fluorination: Ring Opening of Oxabicyclic Alkenes

(2012) Jiangtao Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Indeno[1,2-c]furans via a Pd-Catalyzed Bicyclization of 2-Alkynyliodobenzene and Propargylic Alcohol

(2012) Jisong Jin et al.   JOURNAL OF ORGANIC CHEMISTRY

3-Alkenylation or 3-Alkylation of Indole with Propargylic Alcohols: Construction of 3,4-Dihydrocyclopenta[b]indole and 1,4-Dihydrocyclopenta[b]indole in the Presence of Different Catalysts

(2012) Li Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Synthesis of Monofluoroalkyl α,β-Unsaturated Ketones From Allenyl Carbinol Esters Mediated by Gold and Selectfluor

(2012) Zhuang Jin et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition metal-catalyzed fluorination of multi carbon–carbon bonds: new strategies for fluorinated heterocycles

(2012) Guosheng Liu   ORGANIC & BIOMOLECULAR CHEMISTRY

Novel Strategies for Fluorine-18 Radiochemistry

(2011) Ryan Littich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition metal catalysis and nucleophilic fluorination

(2011) Charlotte Hollingworth et al.   CHEMICAL COMMUNICATIONS

Mechanistic Investigations of Cooperative Catalysis in the Enantioselective Fluorination of Epoxides

(2011) Julia A. Kalow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in the Application of SelectfluorTMF-TEDA-BF4 as a Versatile Mediator or Catalyst in Organic Synthesis

(2011) Stojan Stavber   MOLECULES

Gold-Catalyzed Synthesis of α-Fluoro Acetals and α-Fluoro Ketones from Alkynes

(2010) Teresa de Haro et al.   ADVANCED SYNTHESIS & CATALYSIS

The C–F bond as a conformational tool in organic and biological chemistry

(2010) Luke Hunter   Beilstein Journal of Organic Chemistry

Domino gold-catalyzed rearrangement and fluorination of propargyl acetates

(2010) Teresa de Haro et al.   CHEMICAL COMMUNICATIONS

Fluorine in health care: Organofluorine containing blockbuster drugs

(2010) David O’Hagan   JOURNAL OF FLUORINE CHEMISTRY

Enantioselective Ring Opening of Epoxides by Fluoride Anion Promoted by a Cooperative Dual-Catalyst System

(2010) Julia A. Kalow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Diastereoselective Reduction of α-Fluoroimines

(2010) Roy M. Malamakal et al.   ORGANIC LETTERS

Enantioenriched 1-aryl-2-fluoroethylamines. Efficient lipase-catalysed resolution and limitations to the Mitsunobu inversion protocol

(2010) Thor Håkon Krane Thvedt et al.   TETRAHEDRON

The Organometallic Fluorine Chemistry of Palladium and Rhodium: Studies toward Aromatic Fluorination

(2009) Vladimir V. Grushin   ACCOUNTS OF CHEMICAL RESEARCH

The Design and Development of Fesoterodine as a Prodrug of 5- Hydroxymethyl Tolterodine (5-HMT), the Active Metabolite of Tolterodine

(2009) B. Malhotra et al.   CURRENT MEDICINAL CHEMISTRY

Fesoterodine

(2009) Kate McKeage et al.   DRUGS

Fluorine in medicinal chemistry: a century of progress and a 60-year retrospective of selected highlights

(2009) Robert Filler et al.   Future Medicinal Chemistry

Ruthenium-catalysed asymmetric transfer hydrogenation of para-substituted α-fluoroacetophenones

(2009) Erik Fuglseth et al.   JOURNAL OF FLUORINE CHEMISTRY

One-pot α-nucleophilic fluorination of acetophenones in a deep eutectic solvent

(2009) Zizhan Chen et al.   JOURNAL OF FLUORINE CHEMISTRY

Study on the selectivity in the electrophilic monofluorination of 2,3-allenoates with Selectfluor™: an efficient synthesis of 4-fluoro-2(5H)-furanones and 3-fluoro-4-oxo-2(E)-alkenoates

(2009) Bo Lü et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Molecular Imaging with PET

(2008) Simon M. Ametamey et al.   CHEMICAL REVIEWS

Nucleophilic Fluorination of Triflates by Tetrabutylammonium Bifluoride

(2008) Kyu-Young Kim et al.   JOURNAL OF ORGANIC CHEMISTRY

An Efficient Approach for Monofluorination via Highly Regioselective Fluorohydroxylation Reaction of 3-Aryl-1,2-allenes with Selectfluor

(2008) Chao Zhou et al.   ORGANIC LETTERS

Electrophilic and nucleophilic side chain fluorination of para-substituted acetophenones

(2008) Erik Fuglseth et al.   TETRAHEDRON

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS