Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

(2015) Amal M. El-Naggar et al.   CANCER CELL

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

(2015) Thomas R. Cox et al.   NATURE

Sarcomas

(2015) Josephine H. HaDuong et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Suppression of Deacetylase SIRT1 Mediates Tumor-Suppressive NOTCH Response and Offers a Novel Treatment Option in Metastatic Ewing Sarcoma

(2014) J. Ban et al.   CANCER RESEARCH

Cyclophosphamide Compared With Ifosfamide in Consolidation Treatment of Standard-Risk Ewing Sarcoma: Results of the Randomized Noninferiority Euro-EWING99-R1 Trial

(2014) Marie-Cécile Le Deley et al.   JOURNAL OF CLINICAL ONCOLOGY

Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53

(2014) Wietske van der Ent et al.   JOURNAL OF PATHOLOGY

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma

(2014) Aashi Chaturvedi et al.   MOLECULAR BIOLOGY OF THE CELL

Stress-Induced CXCR4 Promotes Migration and Invasion of Ewing Sarcoma

(2014) Melanie A. Krook et al.   MOLECULAR CANCER RESEARCH

The Genomic Landscape of Pediatric Ewing Sarcoma

(2014) B. D. Crompton et al.   Cancer Discovery

Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations

(2014) F. Tirode et al.   Cancer Discovery

The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation

(2014) Andrew S. Brohl et al.   PLoS Genetics

αTAT1 catalyses microtubule acetylation at clathrin-coated pits

(2013) Guillaume Montagnac et al.   NATURE

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis

(2013) Gautier Stoll et al.   NUCLEIC ACIDS RESEARCH

Lysyl Oxidase Is Downregulated by the EWS/FLI1 Oncoprotein and Its Propeptide Domain Displays Tumor Supressor Activities in Ewing Sarcoma Cells

(2013) Noelia Agra et al.   PLoS One

Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma

(2012) Sophie Postel-Vinay et al.   NATURE GENETICS

MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor

(2012) G-A Franzetti et al.   ONCOGENE

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

(2012) S Sankar et al.   ONCOGENE

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

(2012) Veerander P. S. Ghotra et al.   PLoS One

The First European Interdisciplinary Ewing Sarcoma Research Summit

(2012) Heinrich Kovar et al.   Frontiers in Oncology

Reversible adaptive plasticity: a mechanism for neuroblastoma cell heterogeneity and chemo-resistance

(2012) Lina Chakrabarti   Frontiers in Oncology

Molecular Pathogenesis of Ewing Sarcoma: New Therapeutic and Transcriptional Targets

(2011) Stephen L. Lessnick et al.   Annual Review of Pathology-Mechanisms of Disease

Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

(2011) Patrick J. Grohar et al.   JNCI-Journal of the National Cancer Institute

Hypoxia Modulates EWS-FLI1 Transcriptional Signature and Enhances the Malignant Properties of Ewing's Sarcoma Cells In vitro

(2010) D. N. T. Aryee et al.   CANCER RESEARCH

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Recent advances in the molecular pathogenesis of Ewing's sarcoma

(2010) E C Toomey et al.   ONCOGENE

SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity

(2010) A Barbáchano et al.   ONCOGENE

Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells

(2009) Preamrudee Poomthavorn et al.   ENDOCRINE-RELATED CANCER

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Quantitative imaging assay for NF-κB nuclear translocation in primary human macrophages

(2007) Mahdad Noursadeghi et al.   JOURNAL OF IMMUNOLOGICAL METHODS