MUC1-C integrates PD-L1 induction with repression of immune effectors in non-small-cell lung cancer

MUC1-C drives MYC in multiple myeloma

(2016) Ashujit Tagde et al.   BLOOD

Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas

(2016) Audrey Bouillez et al.   CANCER RESEARCH

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

(2016) S. Koyama et al.   CANCER RESEARCH

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle Formulation

(2015) M. Hasegawa et al.   CLINICAL CANCER RESEARCH

A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition

(2015) M. P. Mak et al.   CLINICAL CANCER RESEARCH

Immunotherapy for non-small cell lung cancer: current concepts and clinical trials

(2015) Marissa Mayor et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Prognostic Significance of Mucin Antigen MUC1 in Various Human Epithelial Cancers

(2015) Feng Xu et al.   MEDICINE

MUC1-C activates the TAK1 inflammatory pathway in colon cancer

(2015) H Takahashi et al.   ONCOGENE

Immunologic Checkpoint Blockade in Lung Cancer

(2015) Martin Reck et al.   SEMINARS IN ONCOLOGY

Dual roles of TLR7 in the lung cancer microenvironment

(2015) Marion Dajon et al.   OncoImmunology

Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB

(2015) Kavitha Gowrishankar et al.   PLoS One

Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target

(2015) Deepak Raina et al.   PLoS One

MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells

(2015) Akriti Kharbanda et al.   Oncotarget

MUC1 drives epithelial–mesenchymal transition in renal carcinoma through Wnt/β-catenin pathway and interaction with SNAIL promoter

(2014) Viviane Gnemmi et al.   CANCER LETTERS

TLR7 Promotes Tumor Progression, Chemotherapy Resistance, and Poor Clinical Outcomes in Non-Small Cell Lung Cancer

(2014) S. Chatterjee et al.   CANCER RESEARCH

Targeting the Oncogenic MUC1-C Protein Inhibits Mutant EGFR-Mediated Signaling and Survival in Non-Small Cell Lung Cancer Cells

(2014) A. Kharbanda et al.   CLINICAL CANCER RESEARCH

An AMPK-Independent Signaling Pathway Downstream of the LKB1 Tumor Suppressor Controls Snail1 and Metastatic Potential

(2014) Jonathan M. Goodwin et al.   MOLECULAR CELL

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

RTCGAToolbox: A New Tool for Exporting TCGA Firehose Data

(2014) Mehmet Kemal Samur   PLoS One

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

(2014) Limo Chen et al.   Nature Communications

Toll-Like Receptor 9 in Breast Cancer

(2014) Jouko Sandholm et al.   Frontiers in Immunology

Iterative rank-order normalization of gene expression microarray data

(2013) Eric A Welsh et al.   BMC BIOINFORMATICS

MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial–mesenchymal transition

(2013) H Rajabi et al.   ONCOGENE

NF-κB Plays a Key Role in Inducing CD274 Expression in Human Monocytes after Lipopolysaccharide Treatment

(2013) Gang Huang et al.   PLoS One

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

(2013) E. A. Akbay et al.   Cancer Discovery

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

(2012) D W Kufe   ONCOGENE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non-Small-Cell Lung Cancer Patients

(2011) Y. Xie et al.   CLINICAL CANCER RESEARCH

Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer

(2011) Noriaki Sunaga et al.   INTERNATIONAL JOURNAL OF CANCER

Absent Toll-like receptor-9 expression predicts poor prognosis in renal cell carcinoma

(2011) Hanna Ronkainen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells

(2011) D. Raina et al.   MOLECULAR CANCER THERAPEUTICS

MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients

(2010) Dhara M MacDermed et al.   BMC Medical Genomics

Functional targeting of the MUC1 oncogene in human cancers

(2010) Donald W. Kufe   CANCER BIOLOGY & THERAPY

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

(2010) Julien Cherfils-Vicini et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression and prognostic relevance of MUC1 in stage IB non-small cell lung cancer

(2010) Dongrong Situ et al.   MEDICAL ONCOLOGY

Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

(2010) Jun Hou et al.   PLoS One

Nuclear factor κB (NF-κB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist

(2009) Jongdae Lee et al.   BIOCHEMICAL JOURNAL

MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor- B p65 Transcription Factor

(2009) R. Ahmad et al.   CANCER RESEARCH

MUC1-Induced Transcriptional Programs Associated with Tumorigenesis Predict Outcome in Breast and Lung Cancer

(2009) N. N. Khodarev et al.   CANCER RESEARCH

Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

(2009) Xiaoyu Hu et al.   IMMUNOLOGICAL REVIEWS

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH