The circadian clock, metabolism and obesity

Liver-derived ketone bodies are necessary for food anticipation

(2016) Rohit Chavan et al.   Nature Communications

Time-fixed feeding prevents obesity induced by chronic advances of light/dark cycles in mouse models of jet-lag/shift work

(2015) Hideaki Oike et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Smartphone App Reveals Erratic Diurnal Eating Patterns in Humans that Can Be Modulated for Health Benefits

(2015) Shubhroz Gill et al.   Cell Metabolism

Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age

(2015) Ziv Zwighaft et al.   Cell Metabolism

Circadian Dysfunction Induces Leptin Resistance in Mice

(2015) Nicole M. Kettner et al.   Cell Metabolism

Leptin Normalizes Photic Synchronization in Maleob/obMice, via Indirect Effects on the Suprachiasmatic Nucleus

(2015) Edith Grosbellet et al.   ENDOCRINOLOGY

Shifting the feeding of mice to the rest phase creates metabolic alterations, which, on their own, shift the peripheral circadian clocks by 12 hours

(2015) Atish Mukherji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome

(2015) Atish Mukherji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural selection against a circadian clock gene mutation in mice

(2015) Kamiel Spoelstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic   cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

(2015) M. Perelis et al.   SCIENCE

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

Synchronization of Biological Clock Neurons by Light and Peripheral Feedback Systems Promotes Circadian Rhythms and Health

(2015) Ashna Ramkisoensing et al.   Frontiers in Neurology

Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome

(2014) Amir Zarrinpar et al.   Cell Metabolism

Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges

(2014) Amandine Chaix et al.   Cell Metabolism

Advances in understanding the interrelations between leptin resistance and obesity

(2014) Haitao Pan et al.   PHYSIOLOGY & BEHAVIOR

Meal frequency and timing in health and disease

(2014) Mark P. Mattson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination

(2013) Min-Dian Li et al.   Cell Metabolism

Timing of food intake predicts weight loss effectiveness

(2013) M Garaulet et al.   INTERNATIONAL JOURNAL OF OBESITY

The nuclear receptor Rev-erbα controls circadian thermogenic plasticity

(2013) Zachary Gerhart-Hines et al.   NATURE

High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women

(2013) Daniela Jakubowicz et al.   Obesity

Molecular architecture of the mammalian circadian clock

(2013) Carrie L. Partch et al.   TRENDS IN CELL BIOLOGY

Role of the circadian clock gene Per2 in adaptation to cold temperature

(2013) Sylvie Chappuis et al.   Molecular Metabolism

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Timed high-fat diet resets circadian metabolism and prevents obesity

(2012) Hadas Sherman et al.   FASEB JOURNAL

The nuclear receptor REV-ERBα is required for the daily balance of carbohydrate and lipid metabolism

(2012) Julien Delezie et al.   FASEB JOURNAL

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

Influence of dark phase restricted high fat feeding on myocardial adaptation in mice

(2012) Ju-Yun Tsai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

The human circadian metabolome

(2012) R. Dallmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Adverse Metabolic Consequences in Humans of Prolonged Sleep Restriction Combined with Circadian Disruption

(2012) O. M. Buxton et al.   Science Translational Medicine

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Impairment of Peripheral Circadian Clocks Precedes Metabolic Abnormalities in ob/ob Mice

(2011) Hitoshi Ando et al.   ENDOCRINOLOGY

Feeding Cues and Injected Nutrients Induce Acute Expression of Multiple Clock Genes in the Mouse Liver

(2011) Hideaki Oike et al.   PLoS One

Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor   (PPAR ) activity

(2011) F. Gachon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of circadian clocks has ramifications for metabolism, brain, and behavior

(2011) I. N. Karatsoreos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the role of PPARs

(2011) Alexandra Montagner et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Circadian Clock-Coordinated 12 Hr Period Rhythmic Activation of the IRE1α Pathway Controls Lipid Metabolism in Mouse Liver

(2010) Gaspard Cretenet et al.   Cell Metabolism

Food Intake during the Normal Activity Phase Prevents Obesity and Circadian Desynchrony in a Rat Model of Night Work

(2010) Roberto Salgado-Delgado et al.   ENDOCRINOLOGY

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

(2010) I. Schmutz et al.   GENES & DEVELOPMENT

Transcriptional repressor TIEG1 regulatesBmal1gene through GC box and controls circadian clockwork

(2010) Tsuyoshi Hirota et al.   GENES TO CELLS

Kruppel-Like Factor KLF10 Is a Link between the Circadian Clock and Metabolism in Liver

(2010) F. Guillaumond et al.   MOLECULAR AND CELLULAR BIOLOGY

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

Physiology of Circadian Entrainment

(2010) Diego A. Golombek et al.   PHYSIOLOGICAL REVIEWS

Light responses of the circadian system in leptin deficient mice

(2010) Maria Assumpció Sans-Fuentes et al.   PHYSIOLOGY & BEHAVIOR

Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications

(2009) Nancy Nader et al.   FASEB JOURNAL

Circadian Timing of Food Intake Contributes to Weight Gain

(2009) Deanna M. Arble et al.   Obesity

Daily rhythms of food-anticipatory behavioral activity do not require the known circadian clock

(2009) K.-F. Storch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

(2009) A. Y.-L. So et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL