Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse

(2016) Jessica L. Billings et al.   ACS Chemical Neuroscience

Clinical Experience With Deferiprone Treatment for Friedreich Ataxia

(2016) Sandra Elincx-Benizri et al.   JOURNAL OF CHILD NEUROLOGY

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease

(2016) Lars Tatenhorst et al.   Acta Neuropathologica Communications

Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice

(2015) David I. Finkelstein et al.   ACS Chemical Neuroscience

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators

(2015) David G. Workman et al.   Metallomics

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo

(2015) Kim-Ann Saal et al.   NEUROBIOLOGY OF DISEASE

Possible involvement of iron-induced oxidative insults in neurodegeneration

(2015) Takeshi Asano et al.   NEUROSCIENCE LETTERS

Rho Kinase Inhibition by Fasudil in the Striatal 6-Hydroxydopamine Lesion Mouse Model of Parkinson Disease

(2014) Lars Tatenhorst et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

Combined Therapy of Iron Chelator and Antioxidant Completely Restores Brain Dysfunction Induced by Iron Toxicity

(2014) Jirapas Sripetchwandee et al.   PLoS One

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

(2013) David Devos et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators

(2013) Orly Weinreb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons

(2013) Zhi Dong Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

The genetics of Parkinson's disease: Progress and therapeutic implications

(2013) Andrew B. Singleton et al.   MOVEMENT DISORDERS

The many faces of alpha-synuclein mutations

(2013) Meike Kasten et al.   MOVEMENT DISORDERS

Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease

(2013) Eugénie Mutez et al.   NEUROBIOLOGY OF DISEASE

Regional siderosis: a new challenge for iron chelation therapy

(2013) Zvi Ioav Cabantchik et al.   Frontiers in Pharmacology

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

(2012) L. Tonges et al.   BRAIN

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetics and iron in the systems biology of Parkinson’s disease and some related disorders

(2012) Claudia Funke et al.   NEUROCHEMISTRY INTERNATIONAL

Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo

(2012) Elodie Angot et al.   PLoS One

A pilot trial of deferiprone for neurodegeneration with brain iron accumulation

(2011) G. Abbruzzese et al.   HAEMATOLOGICA

Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal

(2010) Yang-Sung Sohn et al.   BRITISH JOURNAL OF PHARMACOLOGY

Clioquinol: Review of its Mechanisms of Action and Clinical Uses in Neurodegenerative Disorders

(2010) Silvio R. Bareggi et al.   CNS Neuroscience & Therapeutics

Binding of α-synuclein with Fe(III) and with Fe(II) and biological implications of the resultant complexes

(2009) Yong Peng et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Insights into Zn2+ homeostasis in neurons from experimental and modeling studies

(2008) Robert A. Colvin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The toxicology of Clioquinol☆

(2008) X MAO et al.   TOXICOLOGY LETTERS