Mdivi-1 Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats, Possibly via Inhibition of Drp1-Activated Mitochondrial Fission and Oxidative Stress

A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell death

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Mitochondrial division inhibitor 1 (Mdivi-1) offers neuroprotection through diminishing cell death and improving functional outcome in a mouse model of traumatic brain injury

(2016) Qiong Wu et al.   BRAIN RESEARCH

About the importance of the acute phase of subarachnoid hemorrhage and the chances for successful translation

(2016) Catharina Conzen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mdivi-1 Protects Epileptic Hippocampal Neurons from Apoptosis via Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress in Vitro

(2016) Nanchang Xie et al.   NEUROCHEMICAL RESEARCH

Aneurysmal subarachnoid hemorrhage: pathobiology, current treatment and future directions

(2015) Joseph C Serrone et al.   Expert Review of Neurotherapeutics

Mitochondrial Division Inhibitor 1 Ameliorates Mitochondrial Injury, Apoptosis, and Motor Dysfunction After Acute Spinal Cord Injury in Rats

(2015) Gang Li et al.   NEUROCHEMICAL RESEARCH

Activation of mGluR5 Attenuates Microglial Activation and Neuronal Apoptosis in Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats

(2015) Zong-yong Zhang et al.   NEUROCHEMICAL RESEARCH

Progesterone alleviates acute brain injury via reducing apoptosis and oxidative stress in a rat experimental subarachnoid hemorrhage model

(2015) Jing Cai et al.   NEUROSCIENCE LETTERS

Seizure-Induced Oxidative Stress in Temporal Lobe Epilepsy

(2015) Sreekanth Puttachary et al.   Biomed Research International

Aneurysmal subarachnoid hemorrhage: pathobiology, current treatment and future directions

(2015) Joseph C Serrone et al.   Expert Review of Neurotherapeutics

Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage

(2014) A. Jacobsen et al.   ACTA NEUROLOGICA SCANDINAVICA

Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death

(2014) Ivan Zaja et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of mitochondrial calcium uniporter in regulating mitochondrial fission in the cerebral cortexes of living rats

(2014) Nan Liang et al.   JOURNAL OF NEURAL TRANSMISSION

New insights into the function and regulation of mitochondrial fission

(2013) Hidenori Otera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of mitochondrial fission in neuronal injury in pilocarpine-induced epileptic rats

(2013) X. Qiu et al.   NEUROSCIENCE

A selective inhibitor of Drp1, mdivi-1, protects against cell death of hippocampal neurons in pilocarpine-induced seizures in rats

(2013) Nanchang Xie et al.   NEUROSCIENCE LETTERS

A selective inhibitor of Drp1, mdivi-1, acts against cerebral ischemia/reperfusion injury via an anti-apoptotic pathway in rats

(2013) Ning Zhang et al.   NEUROSCIENCE LETTERS

Early Brain Injury, an Evolving Frontier in Subarachnoid Hemorrhage Research

(2013) Mutsumi Fujii et al.   Translational Stroke Research

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

(2012) J Grohm et al.   CELL DEATH AND DIFFERENTIATION

Role of autophagy in early brain injury after subarachnoid hemorrhage in rats

(2012) Hongbo Zhao et al.   MOLECULAR BIOLOGY REPORTS

The importance of early brain injury after subarachnoid hemorrhage

(2012) Fatima A. Sehba et al.   PROGRESS IN NEUROBIOLOGY

Early brain injury following aneurysmal subarachnoid hemorrhage: emphasis on cellular apoptosis

(2012) Simge Yuksel et al.   Turkish Neurosurgery

High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission

(2010) Tianzheng Yu et al.   ANTIOXIDANTS & REDOX SIGNALING

Aminoguanidine inhibition of iNOS activity ameliorates cerebral vasospasm after subarachnoid hemorrhage in rabbits via restoration of dysfunctional endothelial cells

(2010) Bingjie Zheng et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Simvastatin activates Akt/glycogen synthase kinase-3β signal and inhibits caspase-3 activation after experimental subarachnoid hemorrhage

(2009) Gao Cheng et al.   VASCULAR PHARMACOLOGY

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS