Microglia Loss Contributes to the Development of Major Depression Induced by Different Types of Chronic Stresses

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation

(2016) M M Harraz et al.   MOLECULAR PSYCHIATRY

Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

(2016) J.A. Cobb et al.   NEUROSCIENCE

Pifithrin-� Attenuates Acute Sickness Response to Lipopolysaccharide in C57BL/6J Mice

(2016) Rongping Zhang et al.   PHARMACOLOGY

The Future of Depression Psychopharmacology

(2016) Robert H. Belmaker   CNS SPECTRUMS

Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression

(2015) D. Jeffrey Newport et al.   AMERICAN JOURNAL OF PSYCHIATRY

Ketamine as a promising prototype for a new generation of rapid-acting antidepressants

(2015) Chadi G. Abdallah et al.   Annals of the New York Academy of Sciences

Meta-Analysis of Cytokines and Chemokines in Suicidality: Distinguishing Suicidal Versus Nonsuicidal Patients

(2015) Carmen Black et al.   BIOLOGICAL PSYCHIATRY

Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder

(2015) Rita Haapakoski et al.   BRAIN BEHAVIOR AND IMMUNITY

Beyond Monoamines-Novel Targets for Treatment-Resistant Depression: A Comprehensive Review

(2015) Joshua D. Rosenblat et al.   Current Neuropharmacology

Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus–pituitary–adrenal axis

(2015) Li Cai et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue

(2015) Diana M. Norden et al.   PHYSIOLOGY & BEHAVIOR

Microglia activation regulates GluR1 phosphorylation in chronic unpredictable stress-induced cognitive dysfunction

(2015) Mingchao Liu et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Dynamic structural remodelling of microglia in health and disease: A review of the models, the signals and the mechanisms

(2014) F. Rohan Walker et al.   BRAIN BEHAVIOR AND IMMUNITY

Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2

(2014) E. Lopez-Rivera et al.   CANCER RESEARCH

Health-related Quality of Life, Fatigue, and Depression Under Low-Dose IFN-α Therapy in Melanoma Patients

(2014) Katrin Reuter et al.   JOURNAL OF IMMUNOTHERAPY

Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance

(2014) Wanpeng Cui et al.   JOURNAL OF NEUROSCIENCE

Antidepressant-like effect of nitric oxide synthase inhibitors and sildenafil against lipopolysaccharide-induced depressive-like behavior in mice

(2014) V.S. Tomaz et al.   NEUROSCIENCE

Putative Transcriptomic Biomarkers in the Inflammatory Cytokine Pathway Differentiate Major Depressive Disorder Patients from Control Subjects and Bipolar Disorder Patients

(2014) Timothy R. Powell et al.   PLoS One

WY14643 produces anti-depressant-like effects in mice via the BDNF signaling pathway

(2014) Bo Jiang et al.   PSYCHOPHARMACOLOGY

Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects

(2014) Ole Köhler et al.   JAMA Psychiatry

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

Microglia Actively Regulate the Number of Functional Synapses

(2013) Kyungmin Ji et al.   PLoS One

Synergistic Effects of Celecoxib and Bupropion in a Model of Chronic Inflammation-Related Depression in Mice

(2013) Izaque S. Maciel et al.   PLoS One

Monoamine neurocircuitry in depression and strategies for new treatments

(2013) Michel Hamon et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The secretome signature of reactive glial cells and its pathological implications

(2012) Mithilesh Kumar Jha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Deletion of CREB-Regulated Transcription Coactivator 1 Induces Pathological Aggression, Depression-Related Behaviors, and Neuroplasticity Genes Dysregulation in Mice

(2012) Lionel Breuillaud et al.   BIOLOGICAL PSYCHIATRY

Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline

(2012) M. Hinwood et al.   CEREBRAL CORTEX

The effect of 2,3,4′,5-tetrahydroxystilbene-2-0-β-d glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms

(2012) Xiao-le Xu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge

(2012) Alexander Salazar et al.   HORMONES AND BEHAVIOR

Microglia in development: linking brain wiring to brain environment

(2012) Rosa C. Paolicelli et al.   Neuron Glia Biology

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

 -Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat

(2011) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Minocycline produced antidepressant-like effects on the learned helplessness rats with alterations in levels of monoamine in the amygdala and no changes in BDNF levels in the hippocampus at baseline

(2011) Shiho Arakawa et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

LPS inhibits the effects of fluoxetine on depression-like behavior and hippocampal neurogenesis in rats

(2011) Ying Wang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Docosahexaenoic Acid Suppresses Neuroinflammatory Responses and Induces Heme Oxygenase-1 Expression in BV-2 Microglia: Implications of Antidepressant Effects for Omega-3 Fatty Acids

(2010) Dah-Yuu Lu et al.   NEUROPSYCHOPHARMACOLOGY

Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

(2010) Heath D Schmidt et al.   NEUROPSYCHOPHARMACOLOGY

Cerebral and Peripheral Changes Occurring in Nitric Oxide (NO) Synthesis in a Rat Model of Sleeping Sickness: Identification of Brain iNOS Expressing Cells

(2010) Donia Amrouni et al.   PLoS One

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

Stress-induced microglial activation may facilitate the progression of neurodegenerative disorders

(2009) Shuei Sugama   MEDICAL HYPOTHESES

Antidepressant-like effects of 3,6′-disinapoyl sucrose on hippocampal neuronal plasticity and neurotrophic signal pathway in chronically mild stressed rats

(2009) Yuan Hu et al.   NEUROCHEMISTRY INTERNATIONAL

Differential microglial activation between acute stress and lipopolysaccharide treatment

(2008) Shuei Sugama et al.   JOURNAL OF NEUROIMMUNOLOGY

Antidepressant-like actions of minocycline combined with several glutamate antagonists

(2007) Miguel Molina-Hernández et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY