Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation
出版年份 2016 全文链接
标题
Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation
作者
关键词
-
出版物
MOLECULAR PSYCHIATRY
Volume 21, Issue 3, Pages 313-319
出版商
Springer Nature
发表日期
2016-01-19
DOI
10.1038/mp.2015.211
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics
- (2015) Chadi G. Abdallah et al. Annual Review of Medicine
- Antidepressant actions of ketamine: from molecular mechanisms to clinical practice
- (2015) Lisa M Monteggia et al. CURRENT OPINION IN NEUROBIOLOGY
- Faster, better, stronger: Towards new antidepressant therapeutic strategies
- (2015) Olivia F. O’Leary et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses
- (2014) E. S. Gideons et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment
- (2014) S. J. Shabel et al. SCIENCE
- Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial
- (2013) James W. Murrough et al. AMERICAN JOURNAL OF PSYCHIATRY
- Glutamate-Based Antidepressants: Preclinical Psychopharmacology
- (2013) Andrzej Pilc et al. BIOLOGICAL PSYCHIATRY
- Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics and neuronal synaptic damage in neurodegenerative diseases
- (2011) T Nakamura et al. CELL DEATH AND DIFFERENTIATION
- NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
- (2011) Anita E. Autry et al. NATURE
- The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf+/− heterozygous null mice
- (2011) Jesse S.O. Lindholm et al. NEUROPHARMACOLOGY
- Association of the Small GTPase Rheb with the NMDA Receptor Subunit NR3A
- (2011) Nikolaus J. Sucher et al. NEUROSIGNALS
- Neurotrophin-mediated degradation of histone methyltransferase by S-nitrosylation cascade regulates neuronal differentiation
- (2011) N. Sen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses
- (2010) P. Xia et al. JOURNAL OF NEUROSCIENCE
- Nascent nitrosylases
- (2010) Jonathan S. Stamler et al. NATURE CELL BIOLOGY
- Cracking the moody brain: Lifting the mood with ketamine
- (2010) James W Murrough et al. NATURE MEDICINE
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
- (2010) N. Li et al. SCIENCE
- Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb
- (2009) M. N. Lee et al. MOLECULAR AND CELLULAR BIOLOGY
- From synapse to nucleus: Novel targets for treating depression
- (2009) Herbert E. Covington et al. NEUROPHARMACOLOGY
- Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
- (2008) Nilkantha Sen et al. NATURE CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started