Ursolic acid activates the TGR5 receptor to enhance GLP-1 secretion in type 1-like diabetic rats

Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties

(2017) Simone Tasca Cargnin et al.   FOOD CHEMISTRY

Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion

(2016) M. Hansen et al.   DIABETES OBESITY & METABOLISM

Ursolic acid (UA): A metabolite with promising therapeutic potential

(2016) Dharambir Kashyap et al.   LIFE SCIENCES

Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules

(2016) Bryan L. Copple et al.   PHARMACOLOGICAL RESEARCH

Development of betulinic acid as an agonist of TGR5 receptor using a new in vitro assay

(2016) Juei-Tang Cheng et al.   Drug Design Development and Therapy

The regulation of function, growth and survival of GLP-1-producing L-cells

(2015) R. E. Kuhre et al.   CLINICAL SCIENCE

Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist

(2015) Sameer Agarwal et al.   ACS Medicinal Chemistry Letters

Highly lipophilic 3-epi-betulinic acid derivatives as potent and selective TGR5 agonists with improved cellular efficacy

(2014) Xiao-yin Wang et al.   ACTA PHARMACOLOGICA SINICA

Ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI-H716 cells via bile acid receptor activation

(2014) Kyong Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT

(2012) Rahul Checker et al.   PLoS One

Eemergence of Promising Therapies in Diabetes Mellitus

(2010) Sindhu Akkati et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

(2010) Thijs W.H. Pols et al.   JOURNAL OF HEPATOLOGY

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Structure−Activity Relationship Study of Betulinic Acid, A Novel and Selective TGR5 Agonist, and Its Synthetic Derivatives: Potential Impact in Diabetes¶

(2009) Cédric Genet et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pentacyclic Triterpene Distribution in Various Plants – Rich Sources for a New Group of Multi-Potent Plant Extracts

(2009) Sebastian Jäger et al.   MOLECULES

Ursolic acid: An anti- and pro-inflammatory triterpenoid

(2008) Yasutaka Ikeda et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Role of Incretins in Glucose Homeostasis and Diabetes Treatment

(2008) W. Kim et al.   PHARMACOLOGICAL REVIEWS