标题
Dynamic regulation of CD28 conformation and signaling by charged lipids and ions
作者
关键词
-
出版物
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 24, Issue 12, Pages 1081-1092
出版商
Springer Nature
发表日期
2017-10-19
DOI
10.1038/nsmb.3489
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
- (2017) Enfu Hui et al. SCIENCE
- Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent
- (2017) Alice O. Kamphorst et al. SCIENCE
- CD28 costimulatory signals in T lymphocyte activation: Emerging functions beyond a qualitative and quantitative support to TCR signalling
- (2016) Nicla Porciello et al. CYTOKINE & GROWTH FACTOR REVIEWS
- CD28 Costimulation: From Mechanism to Therapy
- (2016) Jonathan H. Esensten et al. IMMUNITY
- Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling
- (2016) Jessica Dobbins et al. Science Signaling
- Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling
- (2016) Jessica Dobbins et al. Science Signaling
- TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes
- (2015) Youg Raj Thaker et al. IMMUNOLOGY LETTERS
- Requirement for CD28 in Effector Regulatory T Cell Differentiation, CCR6 Induction, and Skin Homing
- (2015) Ruan Zhang et al. JOURNAL OF IMMUNOLOGY
- The pharmacology of second-generation chimeric antigen receptors
- (2015) Sjoukje J. C. van der Stegen et al. NATURE REVIEWS DRUG DISCOVERY
- Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor
- (2015) Ruijun Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunosuppressive minimization with mTOR inhibitors and belatacept
- (2015) Fritz Diekmann TRANSPLANT INTERNATIONAL
- Acidic phospholipids govern the enhanced activation of IgG-B cell receptor
- (2015) Xiangjun Chen et al. Nature Communications
- Digital response in T cells: to be or not to be
- (2014) Felix Wertek et al. CELL RESEARCH
- CD28 ligation in the absence of TCR stimulation up-regulates IL-17A and pro-inflammatory cytokines in relapsing-remitting multiple sclerosis T lymphocytes
- (2014) Cristina Camperio et al. IMMUNOLOGY LETTERS
- Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line
- (2014) H.-T. Ma et al. JOURNAL OF IMMUNOLOGY
- Membrane Association of the CD3 Signaling Domain Is Required for Optimal T Cell Development and Function
- (2014) M. L. Bettini et al. JOURNAL OF IMMUNOLOGY
- Insights into the initiation of TCR signaling
- (2014) Arup K Chakraborty et al. NATURE IMMUNOLOGY
- Ionic protein–lipid interaction at the plasma membrane: what can the charge do?
- (2014) Lunyi Li et al. TRENDS IN BIOCHEMICAL SCIENCES
- CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection
- (2014) Michelle A Linterman et al. eLife
- The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor
- (2013) S.-P. Cordoba et al. BLOOD
- A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion in CD4+ T Cells
- (2013) Jun Huang et al. IMMUNITY
- CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+T cell response
- (2013) Marc Martínez-Llordella et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cross Talk between CD3 and CD28 Is Spatially Modulated by Protein Lateral Mobility
- (2013) K. T. Bashour et al. MOLECULAR AND CELLULAR BIOLOGY
- Ultrasensitive fluorescent proteins for imaging neuronal activity
- (2013) Tsai-Wen Chen et al. NATURE
- Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling
- (2013) Ying Xim Tan et al. NATURE IMMUNOLOGY
- The lymphoid lineage–specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells
- (2013) Yinming Liang et al. NATURE IMMUNOLOGY
- CD28 and ITK signals regulate autoreactive T cell trafficking
- (2013) Nitya Jain et al. NATURE MEDICINE
- Rule-based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems
- (2013) Lily A. Chylek et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Systems Model of T Cell Receptor Proximal Signaling Reveals Emergent Ultrasensitivity
- (2013) Himadri Mukhopadhyay et al. PLoS Computational Biology
- Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells
- (2013) Geoff P O'Donoghue et al. eLife
- Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain
- (2012) Etienne Gagnon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Divalent Cation-Induced Cluster Formation by Polyphosphoinositides in Model Membranes
- (2012) Yu-Hsiu Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids
- (2012) Xiaoshan Shi et al. NATURE
- Disentangling nestedness from models of ecological complexity
- (2012) Alex James et al. NATURE
- A novel association between filamin A and NF-κB inducing kinase couples CD28 to inhibitor of NF-κB kinase α and NF-κB activation
- (2011) Michela Muscolini et al. IMMUNOLOGY LETTERS
- The CD3 Subunit Contains a Phosphoinositide-Binding Motif That Is Required for the Stable Accumulation of TCR-CD3 Complex at the Immunological Synapse
- (2011) L. M. DeFord-Watts et al. JOURNAL OF IMMUNOLOGY
- Second messenger role for Mg2+ revealed by human T-cell immunodeficiency
- (2011) Feng-Yen Li et al. NATURE
- Membrane protein sequestering by ionic protein–lipid interactions
- (2011) Geert van den Bogaart et al. NATURE
- A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28
- (2011) Kok-Fai Kong et al. NATURE IMMUNOLOGY
- Basic residues in the T-cell receptor cytoplasmic domain mediate membrane association and modulate signaling
- (2011) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI
- (2010) Patrick G. Hogan et al. Annual Review of Immunology
- An Enigmatic Tail of CD28 Signaling
- (2010) J. S. Boomer et al. Cold Spring Harbor Perspectives in Biology
- Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors
- (2009) R Westhovens et al. ANNALS OF THE RHEUMATIC DISEASES
- Transmembrane protein topology prediction using support vector machines
- (2009) Timothy Nugent et al. BMC BIOINFORMATICS
- Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
- (2009) Jayajit Das et al. CELL
- CD28 and CTLA-4 coreceptor expression and signal transduction
- (2009) Christopher E. Rudd et al. IMMUNOLOGICAL REVIEWS
- The Cytoplasmic Tail of the T Cell Receptor CD3 Subunit Contains a Phospholipid-Binding Motif that Regulates T Cell Functions
- (2009) L. M. DeFord-Watts et al. JOURNAL OF IMMUNOLOGY
- Targeted Knock-In Mice Expressing Mutations of CD28 Reveal an Essential Pathway for Costimulation
- (2009) L. F. Dodson et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif
- (2008) Chenqi Xu et al. CELL
- Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C θ Translocation
- (2008) Tadashi Yokosuka et al. IMMUNITY
- CD28 stimulation triggers NF- B activation through the CARMA1-PKC -Grb2/Gads axis
- (2008) K. Takeda et al. INTERNATIONAL IMMUNOLOGY
- Ca2+microdomains near plasma membrane Ca2+channels: impact on cell function
- (2008) Anant B. Parekh JOURNAL OF PHYSIOLOGY-LONDON
- Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
- (2008) Masatsugu Oh-hora et al. NATURE IMMUNOLOGY
- Variability and Robustness in T Cell Activation from Regulated Heterogeneity in Protein Levels
- (2008) O. Feinerman et al. SCIENCE
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