Integration of optogenetics with complementary methodologies in systems neuroscience

Cognitive neuroscience: In search of lost time

(2017) Noah P. Young et al.   NATURE

Communication in Neural Circuits: Tools, Opportunities, and Challenges

(2016) Talia N. Lerner et al.   CELL

Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences

(2016) Li Ye et al.   CELL

Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation

(2016) Gillian A. Matthews et al.   CELL

Targeting Neural Circuits

(2016) Priyamvada Rajasethupathy et al.   CELL

Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution

(2016) Emily Lauren Sylwestrak et al.   CELL

Identification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin fromProteomonas sulcata

(2016) Jonas Wietek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making

(2016) Kelly A. Zalocusky et al.   NATURE

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

(2016) Catherine A. Marcinkiewcz et al.   NATURE

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

(2016) Benjamin E Deverman et al.   NATURE BIOTECHNOLOGY

Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain

(2016) Christina K Kim et al.   NATURE METHODS

Biophysical constraints of optogenetic inhibition at presynaptic terminals

(2016) Mathias Mahn et al.   NATURE NEUROSCIENCE

Direct Ventral Hippocampal-Prefrontal Input Is Required for Anxiety-Related Neural Activity and Behavior

(2016) Nancy Padilla-Coreano et al.   NEURON

Rabies Virus CVS-N2c ΔG Strain Enhances Retrograde Synaptic Transfer and Neuronal Viability

(2016) Thomas R. Reardon et al.   NEURON

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

(2016) Erin S. Calipari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Competition between engrams influences fear memory formation and recall

(2016) A. J. Rashid et al.   SCIENCE

A Look Inside the Brain

(2016) Karl Deisseroth   SCIENTIFIC AMERICAN

Physical limits to magnetogenetics

(2016) Markus Meister   eLife

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Anion channelrhodopsins for inhibitory cardiac optogenetics

(2016) Elena G. Govorunova et al.   Scientific Reports

Neural Representations of Unconditioned Stimuli in Basolateral Amygdala Mediate Innate and Learned Responses

(2015) Felicity Gore et al.   CELL

Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping

(2015) Kevin T. Beier et al.   CELL

Elucidating an Affective Pain Circuit that Creates a Threat Memory

(2015) Sung Han et al.   CELL

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

(2015) Talia N. Lerner et al.   CELL

Decoding Neural Circuits that Control Compulsive Sucrose Seeking

(2015) Edward H. Nieh et al.   CELL

GABAergic Projections from Lateral Hypothalamus to Paraventricular Hypothalamic Nucleus Promote Feeding

(2015) Z. Wu et al.   JOURNAL OF NEUROSCIENCE

Viral-genetic tracing of the input–output organization of a central noradrenaline circuit

(2015) Lindsay A. Schwarz et al.   NATURE

Projections from neocortex mediate top-down control of memory retrieval

(2015) Priyamvada Rajasethupathy et al.   NATURE

Acute off-target effects of neural circuit manipulations

(2015) Timothy M. Otchy et al.   NATURE

Hippocampal–prefrontal input supports spatial encoding in working memory

(2015) Timothy Spellman et al.   NATURE

A direct GABAergic output from the basal ganglia to frontal cortex

(2015) Arpiar Saunders et al.   NATURE

Basomedial amygdala mediates top-down control of anxiety and fear

(2015) Avishek Adhikari et al.   NATURE

Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

(2015) Sung Il Park et al.   NATURE BIOTECHNOLOGY

Voltage sensors: challenging, but with potential

(2015) Nina Vogt   NATURE METHODS

Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice

(2015) Kate L Montgomery et al.   NATURE METHODS

Optogenetics: 10 years of microbial opsins in neuroscience

(2015) Karl Deisseroth   NATURE NEUROSCIENCE

Closed-Loop and Activity-Guided Optogenetic Control

(2015) Logan Grosenick et al.   NEURON

Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity

(2015) Andre Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor

(2015) Y. Gong et al.   SCIENCE

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

(2015) E. A. Ferenczi et al.   SCIENCE

Wireless magnetothermal deep brain stimulation

(2015) R. Chen et al.   SCIENCE

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

Engram cells retain memory under retrograde amnesia

(2015) T. J. Ryan et al.   SCIENCE

Optodynamic simulation of β-adrenergic receptor signalling

(2015) Edward R. Siuda et al.   Nature Communications

Sonogenetics is a non-invasive approach to activating neurons in Caenorhabditis elegans

(2015) Stuart Ibsen et al.   Nature Communications

Chronic Optogenetic Activation Augments Aβ Pathology in a Mouse Model of Alzheimer Disease

(2015) Kaoru Yamamoto et al.   Cell Reports

Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool

(2015) Michiel van Wyk et al.   PLOS BIOLOGY

Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

(2015) Yael Mandelblat-Cerf et al.   eLife

Optical Neural Interfaces

(2014) Melissa R. Warden et al.   Annual Review of Biomedical Engineering

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Frequency-Dependent, Cell Type-Divergent Signaling in the Hippocamposeptal Projection

(2014) J. Mattis et al.   JOURNAL OF NEUROSCIENCE

Manipulating a "Cocaine Engram" in Mice

(2014) H.-L. Hsiang et al.   JOURNAL OF NEUROSCIENCE

Scalable control of mounting and attack by Esr1+ neurons in the ventromedial hypothalamus

(2014) Hyosang Lee et al.   NATURE

The participation of cortical amygdala in innate, odour-driven behaviour

(2014) Cory M. Root et al.   NATURE

Bidirectional switch of the valence associated with a hippocampal contextual memory engram

(2014) Roger L. Redondo et al.   NATURE

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Simultaneous all-optical manipulation and recording of neural circuit activity with cellular resolution in vivo

(2014) Adam M Packer et al.   NATURE METHODS

Targeting cells with single vectors using multiple-feature Boolean logic

(2014) Lief E Fenno et al.   NATURE METHODS

Rational design of a high-affinity, fast, red calcium indicator R-CaMP2

(2014) Masatoshi Inoue et al.   NATURE METHODS

Single rodent mesohabenular axons release glutamate and GABA

(2014) David H Root et al.   NATURE NEUROSCIENCE

Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields

(2014) John Peter Rickgauer et al.   NATURE NEUROSCIENCE

High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor

(2014) François St-Pierre et al.   NATURE NEUROSCIENCE

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice

(2014) Angela Kolodziej et al.   NEUROIMAGE

Spatially Selective Holographic Photoactivation and Functional Fluorescence Imaging in Freely Behaving Mice with a Fiberscope

(2014) Vivien Szabo et al.   NEURON

Optogenetic activation of septal cholinergic neurons suppresses sharp wave ripples and enhances theta oscillations in the hippocampus

(2014) Marie Vandecasteele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Inhibition in the Hippocampus Supports Fear Learning

(2014) M. Lovett-Barron et al.   SCIENCE

Structure-Guided Transformation of Channelrhodopsin into a Light-Activated Chloride Channel

(2014) A. Berndt et al.   SCIENCE

Conversion of Channelrhodopsin into a Light-Gated Chloride Channel

(2014) J. Wietek et al.   SCIENCE

Enhancement of encoding and retrieval functions through theta phase-specific manipulation of hippocampus

(2014) Joshua H Siegle et al.   eLife

Mapping Brain Metabolic Connectivity in Awake Rats with  PET and Optogenetic Stimulation

(2013) P. K. Thanos et al.   JOURNAL OF NEUROSCIENCE

Diverging neural pathways assemble a behavioural state from separable features in anxiety

(2013) Sung-Yon Kim et al.   NATURE

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Functional labeling of neurons and their projections using the synthetic activity–dependent promoter E-SARE

(2013) Takashi Kawashima et al.   NATURE METHODS

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

(2013) John Y Lin et al.   NATURE NEUROSCIENCE

Long-term dynamics of CA1 hippocampal place codes

(2013) Yaniv Ziv et al.   NATURE NEUROSCIENCE

A Unique Population of Ventral Tegmental Area Neurons Inhibits the Lateral Habenula to Promote Reward

(2013) Alice M. Stamatakis et al.   NEURON

BLA to vHPC Inputs Modulate Anxiety-Related Behaviors

(2013) Ada C. Felix-Ortiz et al.   NEURON

Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus

(2013) Mazen A. Kheirbek et al.   NEURON

Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations

(2013) Casey J. Guenthner et al.   NEURON

Posttraining optogenetic manipulations of basolateral amygdala activity modulate consolidation of inhibitory avoidance memory in rats

(2013) Mary L. Huff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic Dissection of Entorhinal-Hippocampal Functional Connectivity

(2013) S.-J. Zhang et al.   SCIENCE

Creating a False Memory in the Hippocampus

(2013) S. Ramirez et al.   SCIENCE

The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding

(2013) J. H. Jennings et al.   SCIENCE

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

Hierarchical Connectivity and Connection-Specific Dynamics in the Corticospinal-Corticostriatal Microcircuit in Mouse Motor Cortex

(2012) T. Kiritani et al.   JOURNAL OF NEUROSCIENCE

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

(2012) J. Akerboom et al.   JOURNAL OF NEUROSCIENCE

Choice-specific sequences in parietal cortex during a virtual-navigation decision task

(2012) Christopher D. Harvey et al.   NATURE

Monkeys

(2012) Ken Liu   NATURE

Neuron-type-specific signals for reward and punishment in the ventral tegmental area

(2012) Jeremiah Y. Cohen et al.   NATURE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Simultaneous BOLD fMRI and fiber-optic calcium recording in rat neocortex

(2012) Kristina Schulz et al.   NATURE METHODS

Two-photon optogenetics of dendritic spines and neural circuits

(2012) Adam M Packer et al.   NATURE METHODS

Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation

(2012) Rohit Prakash et al.   NATURE METHODS

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Evoked Axonal Oxytocin Release in the Central Amygdala Attenuates Fear Response

(2012) H. Sophie Knobloch et al.   NEURON

Transneuronal tracing of airways-related sensory circuitry using herpes simplex virus 1, strain H129

(2012) A.E. McGovern et al.   NEUROSCIENCE

Generation of a Synthetic Memory Trace

(2012) A. R. Garner et al.   SCIENCE

Dynamics of Retrieval Strategies for Remote Memories

(2011) Inbal Goshen et al.   CELL

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

(2011) Garret D. Stuber et al.   NATURE

Functional identification of an aggression locus in the mouse hypothalamus

(2011) Dayu Lin et al.   NATURE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

(2011) Joanna Mattis et al.   NATURE METHODS

A Cre-Dependent, Anterograde Transsynaptic Viral Tracer for Mapping Output Pathways of Genetically Marked Neurons

(2011) Liching Lo et al.   NEURON

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors

(2011) K. T. Beier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

(2011) A. Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Therapeutic potential of neuropeptide Y (NPY) receptor ligands

(2010) Shaun P. Brothers et al.   EMBO Molecular Medicine

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

(2010) Jin Hyung Lee et al.   NATURE

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Degeneration keeps axons on the straight and narrow

(2010) Bruce D Carter   NATURE NEUROSCIENCE

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

(2010) Daniel A Dombeck et al.   NATURE NEUROSCIENCE

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

(2010) Feng Zhang et al.   Nature Protocols

Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2

(2010) Jessica A Cardin et al.   Nature Protocols

Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond

(2009) Christian Bamann et al.   BIOCHEMISTRY

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

PINP: A New Method of Tagging Neuronal Populations for Identification during In Vivo Electrophysiological Recording

(2009) Susana Q. Lima et al.   PLoS One

CAR-Associated Vesicular Transport of an Adenovirus in Motor Neuron Axons

(2009) Sara Salinas et al.   PLoS Pathogens

Molecular Determinants Differentiating Photocurrent Properties of Two Channelrhodopsins fromChlamydomonas

(2008) Hongxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-speed, miniaturized fluorescence microscopy in freely moving mice

(2008) Benjamin A Flusberg et al.   NATURE METHODS

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE