A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

(2012) Derek K. Chu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

(2012) Marsha Wills-Karp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33

(2012) Monique A.M. Willart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endogenous IL-33 Is Highly Expressed in Mouse Epithelial Barrier Tissues, Lymphoid Organs, Brain, Embryos, and Inflamed Tissues: In Situ Analysis Using a Novel Il-33-LacZ Gene Trap Reporter Strain

(2012) M. Pichery et al.   JOURNAL OF IMMUNOLOGY

Regulation of IL-33 Expression by IFN-γ and Tumor Necrosis Factor-α in Normal Human Epidermal Keratinocytes

(2012) Jitlada Meephansan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice

(2012) K. Yasuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33 and M2a Alveolar Macrophages Promote Lung Defense against the Atypical Fungal Pathogen Pneumocystis murina

(2011) M. P. Nelson et al.   JOURNAL OF IMMUNOLOGY

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

(2011) Ya-Jen Chang et al.   NATURE IMMUNOLOGY

Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice

(2010) Xiang Zhiguang et al.   IMMUNOLOGY LETTERS

Increased IL-33 expression by epithelial cells in bronchial asthma

(2010) David Préfontaine et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of mouse alveolar epithelial cell monolayers

(2009) Lucas DeMaio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma

(2009) Xiaojin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IL-33: a tissue derived cytokine pathway involved in allergic inflammation and asthma

(2009) D. E. Smith   CLINICAL AND EXPERIMENTAL ALLERGY

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

(2009) D. Prefontaine et al.   JOURNAL OF IMMUNOLOGY

Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages

(2009) T. Ohno et al.   JOURNAL OF IMMUNOLOGY

Aspergillus fumigatus germ tube growth and not conidia ingestion induces expression of inflammatory mediator genes in the human lung epithelial cell line A549

(2009) A.-P. Bellanger et al.   JOURNAL OF MEDICAL MICROBIOLOGY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation

(2008) Axel M. Küchler et al.   AMERICAN JOURNAL OF PATHOLOGY

Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling

(2008) Ramzi Fattouh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adjuvant and Anti-Inflammatory Properties of Cigarette Smoke in Murine Allergic Airway Inflammation

(2008) Nancy J. Trimble et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

(2008) Y. Kondo et al.   INTERNATIONAL IMMUNOLOGY

In Vivo-to-In Silico Iterations to Investigate Aeroallergen-Host Interactions

(2008) Alba Llop-Guevara et al.   PLoS One

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One