Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome

Structure of the Elastin-Contractile Units in the Thoracic Aorta and How Genes That Cause Thoracic Aortic Aneurysms and Dissections Disrupt This Structure

(2016) Ashkan Karimi et al.   CANADIAN JOURNAL OF CARDIOLOGY

Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan SyndromeSignificance

(2015) Jason R. Cook et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections

(2015) Julie Backer et al.   CURRENT PHARMACEUTICAL DESIGN

Marfan Sartan: a randomized, double-blind, placebo-controlled trial

(2015) Olivier Milleron et al.   EUROPEAN HEART JOURNAL

Efficacy of losartan vs. atenolol for the prevention of aortic dilation in Marfan syndrome: a randomized clinical trial

(2015) Alberto Forteza et al.   EUROPEAN HEART JOURNAL

Matrix metalloproteinase interactions with collagen and elastin

(2015) Steven R. Van Doren   MATRIX BIOLOGY

C/EBPβ and Nuclear Factor of Activated T Cells Differentially Regulate Adamts-1 Induction by Stimuli Associated with Vascular Remodeling

(2015) Jorge Oller et al.   MOLECULAR AND CELLULAR BIOLOGY

A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection

(2015) Yanxiang Gao et al.   Science China-Life Sciences

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family

(2015) Richard Kelwick et al.   GENOME BIOLOGY

Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38

(2014) A. Escolano et al.   EMBO JOURNAL

Atenolol versus Losartan in Children and Young Adults with Marfan's Syndrome

(2014) Ronald V. Lacro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections

(2013) Dong-chuan Guo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nitric oxide-matrix metaloproteinase-9 interactions: Biological and pharmacological significance

(2013) Shane O'Sullivan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genetics of Thoracic Aortic Aneurysm

(2013) Elisabeth Gillis et al.   CIRCULATION RESEARCH

Conundrum of angiotensin II and TGF-β interactions in aortic aneurysms

(2013) Xiaofeng Chen et al.   CURRENT OPINION IN PHARMACOLOGY

A major role for RCAN1 in atherosclerosis progression

(2013) Nerea Méndez-Barbero et al.   EMBO Molecular Medicine

Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

(2013) Elena M. Gallo et al.   JOURNAL OF CLINICAL INVESTIGATION

ADAMTS-1 and ADAMTS-4 Levels Are Elevated in Thoracic Aortic Aneurysms and Dissections

(2012) Pingping Ren et al.   ANNALS OF THORACIC SURGERY

Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function

(2011) Dirk Hubmacher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

The ADAMTS(L) family and human genetic disorders

(2011) C. Le Goff et al.   HUMAN MOLECULAR GENETICS

Novel MYH11 and ACTA2 mutations reveal a role for enhanced TGFβ signaling in FTAAD

(2011) Marjolijn Renard et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Regulator of calcineurin 1 mediates pathological vascular wall remodeling

(2011) Vanesa Esteban et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGF-β in the pathogenesis and prevention of disease: a matter of aneurysmic proportions

(2010) Harry C. Dietz   JOURNAL OF CLINICAL INVESTIGATION

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT

Syndecan-4 Regulates Subcellular Localization of mTOR Complex2 and Akt Activation in a PKCα-Dependent Manner in Endothelial Cells

(2008) Chohreh Partovian et al.   MOLECULAR CELL