A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase
出版年份 2017 全文链接
标题
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase
作者
关键词
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出版物
Nature Chemical Biology
Volume 13, Issue 9, Pages 943-950
出版商
Springer Nature
发表日期
2017-07-03
DOI
10.1038/nchembio.2420
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water
- (2016) Eduardo Hilario et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases
- (2016) Ying-Nan P. Chen et al. NATURE
- Selective small molecule inhibitor of theMycobacterium tuberculosisfumarate hydratase reveals an allosteric regulatory site
- (2016) Monica Kasbekar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hit and lead criteria in drug discovery for infectious diseases of the developing world
- (2015) Kei Katsuno et al. NATURE REVIEWS DRUG DISCOVERY
- Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum
- (2015) Keith H. Turner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- General and condition-specific essential functions ofPseudomonas aeruginosa
- (2015) Samuel A. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Tuberculosis Drug Discovery and Development Pipeline and Emerging Drug Targets
- (2015) K. Mdluli et al. Cold Spring Harbor Perspectives in Medicine
- Action at a Distance: Allostery and the Development of Drugs to Target Cancer Cell Metabolism
- (2014) Byron DeLaBarre et al. CHEMISTRY & BIOLOGY
- Targeting Bacterial Central Metabolism for Drug Development
- (2014) Paul Murima et al. CHEMISTRY & BIOLOGY
- Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
- (2014) Anil Koul et al. Nature Communications
- Allostery and Substrate Channeling in the Tryptophan Synthase Bienzyme Complex: Evidence for Two Subunit Conformations and Four Quaternary States
- (2013) Dimitri Niks et al. BIOCHEMISTRY
- Allostery in Disease and in Drug Discovery
- (2013) Ruth Nussinov et al. CELL
- Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
- (2013) Yanjia J. Zhang et al. CELL
- Structure-based analysis of thermodynamic and mechanical properties of cavity-containing proteins - case study of plant pathogenesis-related proteins of class 10
- (2013) Mateusz Chwastyk et al. FEBS Journal
- Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis
- (2013) Regina Wilson et al. Nature Chemical Biology
- Advances in the development of new tuberculosis drugs and treatment regimens
- (2013) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32
- (2013) S. A. Stanley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
- (2012) Sarah A. Stanley et al. ACS Chemical Biology
- Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex
- (2012) Michael F. Dunn ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Intravital Imaging of Thymopoiesis Reveals Dynamic Lympho-Epithelial Interactions
- (2012) Isabell Hess et al. IMMUNITY
- Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
- (2012) Anna E Grzegorzewicz et al. Nature Chemical Biology
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- High-throughput protein purification and quality assessment for crystallization
- (2011) Youngchang Kim et al. METHODS
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Exploring and exploiting allostery: Models, evolution, and drug targeting
- (2010) Alessio Peracchi et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Are essential genes really essential?
- (2009) Michael A. D’Elia et al. TRENDS IN MICROBIOLOGY
- High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors
- (2009) Thierry Christophe et al. PLoS Pathogens
- Evolution of bacterial trp operons and their regulation
- (2008) Enrique Merino et al. CURRENT OPINION IN MICROBIOLOGY
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