Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1

The α4β2 nicotinic acetylcholine receptor modulates autism-like behavioral and motor abnormalities in pentylenetetrazol-kindled mice

(2016) Kenshi Takechi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Structural basis for integration of GluD receptors within synaptic organizer complexes

(2016) Jonathan Elegheert et al.   SCIENCE

Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation

(2016) Janet Berrios et al.   Nature Communications

The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology

(2015) Jason A. Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Of mothers and myelin: Aberrant myelination phenotypes in mouse model of Angelman syndrome are dependent on maternal and dietary influences

(2015) Mark D. Grier et al.   BEHAVIOURAL BRAIN RESEARCH

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A

(2015) Jason J. Yi et al.   CELL

Clinical characteristics of children and young adults with co-occurring autism spectrum disorder and epilepsy

(2015) Christelle M. El Achkar et al.   EPILEPSY & BEHAVIOR

Glutamatergic and dopaminergic neurons in the mouse ventral tegmental area

(2015) Tsuyoshi Yamaguchi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopaminergic and glutamatergic microdomains in a subset of rodent mesoaccumbens axons

(2015) Shiliang Zhang et al.   NATURE NEUROSCIENCE

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

GABAergic and glutamatergic efferents of the mouse ventral tegmental area

(2014) Seth R. Taylor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

(2014) Nicole C. Gossan et al.   NUCLEIC ACIDS RESEARCH

The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes

(2014) Shawn McClelland et al.   eLife

Ube3a/E6AP is involved in a subset of MeCP2 functions

(2013) Soeun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Active Form of E6-associated protein (E6AP)/UBE3A Ubiquitin Ligase Is an Oligomer

(2013) Virginia P. Ronchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

(2013) Matthew J Lyst et al.   NATURE NEUROSCIENCE

Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc

(2013) S. Kuhnle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Reduction of the α1 Subunit of Na/K-ATPase Corrects Multiple Hippocampal Phenotypes in Angelman Syndrome

(2013) Hanoch Kaphzan et al.   Cell Reports

Neuronal conditional knockout of NRSF decreases vulnerability to seizures induced by pentylenetetrazol in mice

(2012) M. Liu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome

(2012) Thorfinn T. Riday et al.   JOURNAL OF CLINICAL INVESTIGATION

The Cbln family of proteins interact with multiple signaling pathways

(2012) Peng Wei et al.   JOURNAL OF NEUROCHEMISTRY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

(2012) Linda Madisen et al.   NATURE NEUROSCIENCE

Maternal Loss of Ube3a Produces an Excitatory/Inhibitory Imbalance through Neuron Type-Specific Synaptic Defects

(2012) Michael L. Wallace et al.   NEURON

Deletion of Glutamate Delta-1 Receptor in Mouse Leads to Aberrant Emotional and Social Behaviors

(2012) Roopali Yadav et al.   PLoS One

Induction of excitatory and inhibitory presynaptic differentiation by GluD1

(2011) Kyounghee Ryu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Normal social seeking behavior, hypoactivity and reduced exploratory range in a mouse model of Angelman syndrome

(2011) Melody Allensworth et al.   BMC GENETICS

Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis

(2011) Jari Rossi et al.   Cell Metabolism

Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions

(2011) Keiko Matsuda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice

(2011) Michael M. Scott et al.   JOURNAL OF CLINICAL INVESTIGATION

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

Increased Gene Dosage of Ube3a Results in Autism Traits and Decreased Glutamate Synaptic Transmission in Mice

(2011) S. E. P. Smith et al.   Science Translational Medicine

Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples

(2011) Haley A Scoles et al.   Molecular Autism

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum

(2010) Takeshi Uemura et al.   CELL

Cbln1 Is a Ligand for an Orphan Glutamate Receptor  2, a Bidirectional Synapse Organizer

(2010) K. Matsuda et al.   SCIENCE

Activity-Dependent Repression of Cbln1 Expression: Mechanism for Developmental and Homeostatic Regulation of Synapses in the Cerebellum

(2009) T. Iijima et al.   JOURNAL OF NEUROSCIENCE

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

(2009) Joseph T. Glessner et al.   NATURE

Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy

(2009) Yu-Dong Zhou et al.   NATURE MEDICINE

Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement forMath1

(2009) Matthew F. Rose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

AutDB: a gene reference resource for autism research

(2008) Saumyendra N. Basu et al.   NUCLEIC ACIDS RESEARCH