The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis

Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP

(2017) Dick Wu et al.   NATURE

Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1

(2016) Chantell S. Evans et al.   MOLECULAR BIOLOGY OF THE CELL

N-terminal domain of complexin independently activates calcium-triggered fusion

(2016) Ying Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium

(2016) Ángel Pérez-Lara et al.   eLife

Complexins: small but capable

(2015) Ralf Mohrmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis

(2015) Qiangjun Zhou et al.   NATURE

Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution

(2015) Kyle D Brewer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution

(2015) Kyle D Brewer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Principle of Membrane Fusion in the Cell (Nobel Lecture)

(2014) James Edward Rothman   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics

(2014) Madhurima Dhara et al.   JOURNAL OF CELL BIOLOGY

Processive ATP-driven Substrate Disassembly by theN-Ethylmaleimide-sensitive Factor (NSF) Molecular Machine

(2013) Daniel J. Cipriano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complexin Activates Exocytosis of Distinct Secretory Vesicles Controlled by Different Synaptotagmins

(2013) P. Cao et al.   JOURNAL OF NEUROSCIENCE

Genetic Analysis of Synaptotagmin C2 Domain Specificity in Regulating Spontaneous and Evoked Neurotransmitter Release

(2013) J. Lee et al.   JOURNAL OF NEUROSCIENCE

Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release

(2013) Taulant Bacaj et al.   NEURON

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Syntaxin-1 N-peptide and Habc-domain perform distinct essential functions in synaptic vesicle fusion

(2012) Peng Zhou et al.   EMBO JOURNAL

Complexin Controls Spontaneous and Evoked Neurotransmitter Release by Regulating the Timing and Properties of Synaptotagmin Activity

(2012) R. A. Jorquera et al.   JOURNAL OF NEUROSCIENCE

 E-catenin is an autoinhibited molecule that coactivates vinculin

(2012) H.-J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Post-Translational Modifications and Lipid Binding Profile of Insect Cell-Expressed Full-Length Mammalian Synaptotagmin 1

(2011) Marija Vrljic et al.   BIOCHEMISTRY

Complexin cross-links prefusion SNAREs into a zigzag array

(2011) Daniel Kümmel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synaptotagmin Increases the Dynamic Range of Synapses by Driving Ca2+-Evoked Release and by Clamping a Near-Linear Remaining Ca2+ Sensor

(2011) Olexiy Kochubey et al.   NEURON

Cell biology of Ca2+-triggered exocytosis

(2010) Zhiping P Pang et al.   CURRENT OPINION IN CELL BIOLOGY

Single-molecule FRET–derived model of the synaptotagmin 1–SNARE fusion complex

(2010) Ucheor B Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix

(2010) Xiaofei Yang et al.   NEURON

Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction

(2010) H. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion

(2009) Natalia Gustavsson et al.   BIOSCIENCE REPORTS

The Ca2+Affinity of Synaptotagmin 1 Is Markedly Increased by a Specific Interaction of Its C2B Domain with Phosphatidylinositol 4,5-Bisphosphate

(2009) Anand Radhakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Calcium-Dependent and Calcium-Independent Membrane Binding of Synaptotagmin 1: Two Modes of C2B Binding

(2009) Weiwei Kuo et al.   JOURNAL OF MOLECULAR BIOLOGY

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

(2009) Jun Xu et al.   NATURE NEUROSCIENCE

Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release

(2009) O.-H. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion

(2009) A. Maximov et al.   SCIENCE

Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells

(2008) J.-S. Schonn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA