Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease?

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

(2017) Xavier Montalban et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis

(2017) Luanne M. Metz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome

(2016) Maria Laura Bertolaccini et al.   JOURNAL OF AUTOIMMUNITY

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

(2016) Lewis M. Watkins et al.   Journal of Neuroinflammation

An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

(2016) Michael B. Keough et al.   Nature Communications

Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis

(2015) Mika Komori et al.   ANNALS OF NEUROLOGY

Molecular biomarkers in cerebrospinal fluid of multiple sclerosis patients

(2015) Brit Fitzner et al.   AUTOIMMUNITY REVIEWS

Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration

(2015) Rebecca Scholz et al.   Journal of Neuroinflammation

Hydroxychloroquine reduces microglial activity and attenuates experimental autoimmune encephalomyelitis

(2015) Marcus W. Koch et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Multiple sclerosis—a quiet revolution

(2015) Richard M. Ransohoff et al.   Nature Reviews Neurology

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

(2014) Manuel A. Friese et al.   Nature Reviews Neurology

Iron and neurodegeneration in the multiple sclerosis brain

(2013) Simon Hametner et al.   ANNALS OF NEUROLOGY

Reduction of microglial activity in a model of multiple sclerosis by dipyridamole

(2013) Scott Sloka et al.   Journal of Neuroinflammation

Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

(2013) Jeppe Romme Christensen et al.   PLoS One

Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis

(2013) David W Hampton et al.   Acta Neuropathologica Communications

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis

(2011) Sarah Al-Izki et al.   Multiple Sclerosis Journal

Matrix Metalloproteinase-12 Deficiency Worsens Relapsing-Remitting Experimental Autoimmune Encephalomyelitis in Association with Cytokine and Chemokine Dysregulation

(2009) Angelika Goncalves DaSilva et al.   AMERICAN JOURNAL OF PATHOLOGY

Different methods for control and comparison of the antioxidant properties of vegetables

(2009) Milan Číž et al.   FOOD CONTROL

Glatiramer acetate in combination with minocycline in patients with relapsing—remitting multiple sclerosis: results of a Canadian, multicenter, double-blind, placebo-controlled trial

(2009) LM Metz et al.   Multiple Sclerosis Journal