Enzyme-functionalized DNA nanostructures as tools for organizing and controlling enzymatic reactions

Holliday junction resolvases mediate chloroplast nucleoid segregation

(2017) Yusuke Kobayashi et al.   SCIENCE

Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions

(2017) Andreas Sprengel et al.   Nature Communications

Control of enzyme reactions by a reconfigurable DNA nanovault

(2017) Guido Grossi et al.   Nature Communications

Directional Regulation of Enzyme Pathways through the Control of Substrate Channeling on a DNA Origami Scaffold

(2016) Guoliang Ke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic biofuel cells: 30 years of critical advancements

(2016) Michelle Rasmussen et al.   BIOSENSORS & BIOELECTRONICS

DNA-based control of protein activity

(2016) W. Engelen et al.   CHEMICAL COMMUNICATIONS

Enzymatic reactions in confined environments

(2016) Andreas Küchler et al.   Nature Nanotechnology

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

(2016) Zhao Zhao et al.   Nature Communications

Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

(2016) Yifei Zhang et al.   Nature Communications

One-Step Formation of “Chain-Armor”-Stabilized DNA Nanostructures

(2015) Valentina Cassinelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembly and Purification of Enzyme-Functionalized DNA Origami Structures

(2015) Christopher Timm et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A modular DNA origami-based enzyme cascade nanoreactor

(2015) Veikko Linko et al.   CHEMICAL COMMUNICATIONS

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

Tuning Enzyme Kinetics through Designed Intermolecular Interactions Far from the Active Site

(2015) Yingning Gao et al.   ACS Catalysis

Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability

(2014) Steven D. Perrault et al.   ACS Nano

DNA Crystals as Vehicles for Biocatalysis

(2014) Chun Geng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improved Bioelectrocatalytic Oxidation of Sucrose in a Biofuel Cell with an Enzyme Cascade Assembled on a DNA Scaffold

(2014) Khiem Van Nguyen et al.   JOURNAL OF THE ELECTROCHEMICAL SOCIETY

Virus-Encapsulated DNA Origami Nanostructures for Cellular Delivery

(2014) Joona Mikkilä et al.   NANO LETTERS

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

(2014) Jinglin Fu et al.   Nature Nanotechnology

Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure

(2014) Y. Suzuki et al.   NUCLEIC ACIDS RESEARCH

Non-covalent Single Transcription Factor Encapsulation Inside a DNA Cage

(2013) Robert Crawford et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlled Release of Encapsulated Cargo from a DNA Icosahedron using a Chemical Trigger

(2013) Anusuya Banerjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA Origami Based Visualization System for Studying Site-Specific Recombination Events

(2013) Yuki Suzuki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regulation of an Enzyme Cascade Reaction by a DNA Machine

(2013) Ling Xin et al.   Small

Kinetic Enhancements in DNA–Enzyme Nanostructures Mimic the Sabatier Principle

(2013) Jyun-Liang Lin et al.   ACS Catalysis

Enhancement and Modulation of Enzymatic Activity through Higher-Order Structural Changes of Giant DNA-Protein Multibranch Conjugates

(2012) Sergii Rudiuk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modifying enzyme activity and selectivity by immobilization

(2012) Rafael C. Rodrigues et al.   CHEMICAL SOCIETY REVIEWS

Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures

(2012) Jinglin Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversible Regulation of Protein Binding Affinity by a DNA Machine

(2012) Chao Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Designing biological compartmentalization

(2012) Anna H. Chen et al.   TRENDS IN CELL BIOLOGY

Photo-Cross-Linking-Assisted Thermal Stability of DNA Origami Structures and Its Application for Higher-Temperature Self-Assembly

(2011) Arivazhagan Rajendran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

(2011) Robert J. Conrado et al.   NUCLEIC ACIDS RESEARCH

A Versatile DNA Nanochip for Direct Analysis of DNA Base-Excision Repair

(2010) Masayuki Endo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Control of Biocatalytic Transformations by Programmed DNA Assemblies

(2010) Ronit Freeman et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tuning of Peroxidase Activity by Covalently Tethered DNA Oligonucleotides

(2009) Maximilian Glettenberg et al.   BIOCONJUGATE CHEMISTRY

Supramolecular Cocaine−Aptamer Complexes Activate Biocatalytic Cascades

(2009) Ronit Freeman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Coupled Growth and Division of Model Protocell Membranes

(2009) Ting F. Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembly of Enzymes on DNA Scaffolds: En Route to Biocatalytic Cascades and the Synthesis of Metallic Nanowires

(2009) Ofer I. Wilner et al.   NANO LETTERS

Self-assembly of a nanoscale DNA box with a controllable lid

(2009) Ebbe S. Andersen et al.   NATURE

Enzyme cascades activated on topologically programmed DNA scaffolds

(2009) Ofer I. Wilner et al.   Nature Nanotechnology

DNA-directed assembly of artificial multienzyme complexes

(2008) Joachim Müller et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Self-assembled DNA nanostructures for distance-dependent multivalent ligand–protein binding

(2008) Sherri Rinker et al.   Nature Nanotechnology