Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity
出版年份 2017 全文链接
标题
Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity
作者
关键词
-
出版物
MOLECULES
Volume 22, Issue 3, Pages 426
出版商
MDPI AG
发表日期
2017-03-09
DOI
10.3390/molecules22030426
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- (2017) Chiara Borsari et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case
- (2016) Lydia Siragusa et al. ChemMedChem
- Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs
- (2016) Chiara Borsari et al. JOURNAL OF MEDICINAL CHEMISTRY
- Vorinostat, a histone deacetylase (HDAC) inhibitor, promotes cell cycle arrest and re-sensitizes rituximab- and chemo-resistant lymphoma cells to chemotherapy agents
- (2015) Kai Xue et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- New perspectives for leishmaniasis chemotherapy over current anti-leishmanial drugs: a patent landscape
- (2014) Alice Machado-Silva et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1
- (2014) Abedawn I. Khalaf et al. JOURNAL OF MEDICINAL CHEMISTRY
- Drug Discovery for Neglected Diseases: Molecular Target-Based and Phenotypic Approaches
- (2013) Ian H. Gilbert JOURNAL OF MEDICINAL CHEMISTRY
- Biochemical effects of riluzole on Leishmania parasites
- (2012) Davide Guerrieri et al. EXPERIMENTAL PARASITOLOGY
- An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages
- (2012) Jair L. Siqueira-Neto et al. PLoS Neglected Tropical Diseases
- Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis
- (2012) Tana Bowling et al. International Journal for Parasitology-Drugs and Drug Resistance
- X-ray crystallography: assessment and validation of protein–small molecule complexes for drug discovery
- (2011) David R Cooper et al. Expert Opinion on Drug Discovery
- Drug resistance in human African trypanosomiasis
- (2011) Michael P Barrett et al. Future Microbiology
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structure of recombinantLeishmania donovanipteridine reductase reveals a disordered active site
- (2010) Keri L. Barrack et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Comparison of Bioluminescent Kinase Assays Using Substrate Depletion and Product Formation
- (2010) Cordelle Tanega et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors
- (2010) Nyssa Drinkwater et al. BIOCHEMICAL JOURNAL
- The Kinetoplastid Chemotherapy Revisited: Current Drugs, Recent Advances and Future Perspectives
- (2010) E. Castillo et al. CURRENT MEDICINAL CHEMISTRY
- Virtual Screening Identification of Nonfolate Compounds, Including a CNS Drug, as Antiparasitic Agents Inhibiting Pteridine Reductase
- (2010) Stefania Ferrari et al. JOURNAL OF MEDICINAL CHEMISTRY
- Trypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in mice
- (2010) Natasha Sienkiewicz et al. MOLECULAR MICROBIOLOGY
- One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening
- (2009) Chidochangu P. Mpamhanga et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases
- (2009) Lindsay B. Tulloch et al. JOURNAL OF MEDICINAL CHEMISTRY
- Development of the Predictor hERG Fluorescence Polarization Assay Using a Membrane Protein Enrichment Approach
- (2008) David R. Piper et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7
- (2008) Gerrit Langer et al. Nature Protocols
- Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development
- (2008) A. Cavazzuti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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