Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia

Hybrid Scheme for Modeling Local Field Potentials from Point-Neuron Networks

(2016) Espen Hagen et al.   CEREBRAL CORTEX

New statistical approaches exploit the polygenic architecture of schizophrenia—implications for the underlying neurobiology

(2016) Andrew J Schork et al.   CURRENT OPINION IN NEUROBIOLOGY

Optical sensors to gain mechanistic insights into signaling assemblies

(2016) Brian Tenner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes next

(2016) Neal R Swerdlow et al.   JOURNAL OF PSYCHOPHARMACOLOGY

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

Genome-Editing Technologies: Principles and Applications

(2016) Thomas Gaj et al.   Cold Spring Harbor Perspectives in Biology

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

(2016) Yunpeng Wang et al.   PLoS Genetics

Reconstruction and Simulation of Neocortical Microcircuitry

(2015) Henry Markram et al.   CELL

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsNovelty and Significance

(2015) Marissa LeBlanc et al.   CIRCULATION RESEARCH

Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus

(2015) R S Desikan et al.   MOLECULAR PSYCHIATRY

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

(2015)   NATURE NEUROSCIENCE

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

(2015) Andrew J. Pocklington et al.   NEURON

Calcium signalling and psychiatric disease: bipolar disorder and schizophrenia

(2014) Michael J. Berridge   CELL AND TISSUE RESEARCH

Shared common variants in prostate cancer and blood lipids

(2014) Ole A Andreassen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

(2014) O A Andreassen et al.   MOLECULAR PSYCHIATRY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Computational Psychiatry

(2014) Xiao-Jing Wang et al.   NEURON

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

(2013) Ole A. Andreassen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Modeling Heterogeneous Patients With a Clinical Diagnosis of Schizophrenia With Induced Pluripotent Stem Cells

(2013) Kristen J. Brennand et al.   BIOLOGICAL PSYCHIATRY

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Optogenetic pharmacology for control of native neuronal signaling proteins

(2013) Richard H Kramer et al.   NATURE NEUROSCIENCE

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

The Challenge of Connecting the Dots in the B.R.A.I.N.

(2013) Anna Devor et al.   NEURON

Progress in the Genetics of Polygenic Brain Disorders: Significant New Challenges for Neurobiology

(2013) Steven A. McCarroll et al.   NEURON

Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo

(2013) Ira Espuny-Camacho et al.   NEURON

A Biophysically Detailed Model of Neocortical Local Field Potentials Predicts the Critical Role of Active Membrane Currents

(2013) Michael W. Reimann et al.   NEURON

All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs

(2013) Andrew J. Schork et al.   PLoS Genetics

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

(2013) Ole A. Andreassen et al.   PLoS Genetics

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Calcium signalling remodelling and disease

(2012) Michael J. Berridge   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of CaV2 calcium channels by G protein coupled receptors

(2012) Gerald W. Zamponi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure and function of the β subunit of voltage-gated Ca2+ channels

(2012) Zafir Buraei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Statistical connectivity provides a sufficient foundation for specific functional connectivity in neocortical neural microcircuits

(2012) S. L. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling human cortical development in vitro using induced pluripotent stem cells

(2012) J. Mariani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex

(2012) Matthew Larkum   TRENDS IN NEUROSCIENCES

From antipsychotic to anti-schizophrenia drugs: role of animal models

(2012) Mark A. Geyer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Abundant Pleiotropy in Human Complex Diseases and Traits

(2011) Shanya Sivakumaran et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders

(2011) Holly R. Robertson et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

(2011) E S Lips et al.   MOLECULAR PSYCHIATRY

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

(2011) Günter P. Wagner et al.   NATURE REVIEWS GENETICS

Linking neurodevelopmental and synaptic theories of mental illness through DISC1

(2011) Nicholas J. Brandon et al.   NATURE REVIEWS NEUROSCIENCE

GABAergic interneuron origin of schizophrenia pathophysiology

(2011) Kazu Nakazawa et al.   NEUROPHARMACOLOGY

Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

(2011) Emmanuel Valjent et al.   NEUROPSYCHOPHARMACOLOGY

From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment

(2011) Bita Moghaddam et al.   NEUROPSYCHOPHARMACOLOGY

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

DISC1 at 10: connecting psychiatric genetics and neuroscience

(2011) David J. Porteous et al.   TRENDS IN MOLECULAR MEDICINE

Pervasive Sharing of Genetic Effects in Autoimmune Disease

(2011) Chris Cotsapas et al.   PLoS Genetics

N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: The final common pathway on the road to schizophrenia?

(2010) Joshua T. Kantrowitz et al.   BRAIN RESEARCH BULLETIN

Rethinking schizophrenia

(2010) Thomas R. Insel   NATURE

The Psychiatric GWAS Consortium: Big Science Comes to Psychiatry

(2010) Patrick F. Sullivan   NEURON

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder

(2009) Peter Holmans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Schizophrenia

(2009) Jim van Os et al.   LANCET

Pathway analysis of seven common diseases assessed by genome-wide association

(2008) Ali Torkamani et al.   GENOMICS