Review
Food Science & Technology
Justyna Godos, Agnieszka Micek, Pedro Mena, Daniele Del Rio, Fabio Galvano, Sabrina Castellano, Giuseppe Grosso
Summary: This systematic review examines the relationship between dietary (poly)phenol consumption and cognitive outcomes. The results suggest that a higher intake of flavonoids is associated with better cognitive function and a lower risk of cognitive decline. The meta-analysis also shows an inverse association between flavonoid intake and cognitive impairment and dementia.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Review
Nutrition & Dietetics
Agnieszka Micek, Justyna Godos, Tomasz Brzostek, Agnieszka Gniadek, Claudia Favari, Pedro Mena, Massimo Libra, Daniele Del Rio, Fabio Galvano, Giuseppe Grosso
Summary: The study summarized the relationship between dietary intake of phytoestrogens, blood biomarkers, and cancer-specific mortality and recurrence in patients. It found a significant inverse association between higher dietary isoflavone intake, higher serum/plasma enterolactone concentrations, and overall mortality and cancer recurrence.
Review
Nutrition & Dietetics
Y-Thanh Lu, Madhawa Gunathilake, Jeongseon Kim
Summary: This study reviewed the recent papers and found that the consumption of vegetables and fruits is strongly associated with a reduced risk of endometrial cancer. The results were primarily based on high-quality studies and varied by geographic location.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Renata A. Carnauba, Neuza M. A. Hassimotto, Franco M. Lajolo
Summary: This study estimated total and individual polyphenol intakes in a representative sample of the Brazilian population and identified major dietary contributors. Results showed that non-alcoholic beverages and fruits were the main suppliers of polyphenols, with coffee and orange juice being the main contributors. The study also highlighted the need for improved dietary quality in the Brazilian population for better health outcomes.
BRITISH JOURNAL OF NUTRITION
(2021)
Review
Plant Sciences
Dunja Samec, Erna Karalija, Ivana Sola, Valerija Vujcic Bok, Branka Salopek-Sondi
Summary: Abiotic stressors such as extreme temperatures, drought, flood, light, salt, and heavy metals can affect biological diversity and crop production. Plants have mechanisms to cope with these stressors, and polyphenols, a group of plant-specialized metabolites, play a role in stress protection. Different polyphenol structures have varying biological activities and roles in abiotic stress responses.
Review
Nutrition & Dietetics
Lin Zhu, Yang Shu, Chao Liu, Yawen Zhu, Yao Xiao, Jing Ran, Chunxia Zhang
Summary: This meta-analysis evaluated the relationship between dietary glycemic index (GI), glycemic load (GL), and lung cancer risk, and found that high dietary GI intake is significantly associated with an increased risk of lung cancer in a linear fashion.
Review
Nutrition & Dietetics
Zahra Hayati, Mohammad Asghari Jafarabadi, Saeed Pirouzpanah
Summary: This updated meta-analysis suggests that the pro-inflammatory potential of diet is a risk factor for breast cancer, especially among post-menopausal women, obese groups, and populations in developing countries. Subgroup analysis by methodology can improve results by reducing heterogeneity and have important implications for future epidemiological designs and clinical management.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Chemistry, Applied
Minsun Park, Kwang-Geun Lee
Summary: The study found that roasting significantly increased the volatile compound content and antioxidant activity of omija fruit; roasted omija had significantly higher levels of monoterpenes and sesquiterpenes, and the content of schizandrin was five times higher in roasted omija compared to hot-air dried omija.
Review
Food Science & Technology
Tianze Li, Yang Zhao, Lijun Yuan, Dongdong Zhang, Yifei Feng, Huifang Hu, Dongsheng Hu, Jiaye Liu
Summary: Several epidemiological studies have suggested that higher flavonoid intake is associated with a decreased risk of cardiometabolic disease. This meta-analysis supports the findings, showing a significant association between flavonoid intake and a lower risk of cardiovascular disease, diabetes, and hypertension.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Yue Li, Mingjun Sun
Summary: The meta-analysis found no association between cholesterol consumption and colorectal cancer in cohort studies when comparing high vs low intake categories and assessing dose-response relationship. However, significant associations were found in case-control studies. Additional prospective cohort studies are needed to confirm these findings.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Review
Biochemistry & Molecular Biology
Claudia Musial, Kamila Siedlecka-Kroplewska, Zbigniew Kmiec, Magdalena Gorska-Ponikowska
Summary: The diverse roles of autophagy in cancer development and progression are discussed, highlighting its potential as both a promoter and protector of tumors. The review also emphasizes the increasing use of polyphenols in cancer prevention and treatment, showcasing how these compounds modulate autophagy-induced cancer cell death.
Article
Food Science & Technology
Zhongchao Gai, Songhao Hu, Guoli Gong, Jieqiong Zhao
Summary: This article reviews clinical trials and experimental studies conducted between 2014 and 2023 on the anti-hypertensive effects and mechanisms of dietary polyphenols. The major mechanisms include anti-oxidant, anti-inflammatory, inhibition of ACE activity, and vascular remodeling. The article also discusses the bioavailability of polyphenols and the role of gut microbiota in their metabolism.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Review
Nutrition & Dietetics
Jun Ding, Qi Liu, Ze Liu, Hongbin Guo, Jieyu Liang, Yi Zhang
Summary: Overall, this meta-analysis found a negative association between dietary zinc intake and metabolic syndrome (MetS). The results were consistent across different subgroups, suggesting a potential protective effect of dietary zinc intake against MetS. More high-quality prospective cohort studies are needed to further confirm these findings.
FRONTIERS IN NUTRITION
(2022)
Review
Biology
Carmen Rodriguez-Garcia, Francisco Gutierrez-Santiago
Summary: Colorectal cancer (CRC) is a common cancer with modifiable risk factors including diet, alcohol consumption, and smoking. Natural dietary components have shown chemopreventive activity in CRC through modulation of cellular processes. Post-translational modifications (PTMs) of proteins associated with CRC have gained interest as inappropriate modification is linked to carcinogenesis. This review collects and analyzes the main PTMs associated with CRC, explores the relationship between different proteins susceptible to inappropriate PTMs, and reviews the literature on the role of plant-based dietary compounds in modulating CRC-associated PTMs. The review suggests that plant-based dietary components can correct inappropriate PTMs and promote apoptosis in tumor cells.
Review
Nutrition & Dietetics
Xu Zhang, Hong-Mei Ding, Li-Feng Deng, Guo-Chong Chen, Jie Li, Ze-Yin He, Li Fu, Jia-Fu Li, Fei Jiang, Zeng-Li Zhang, Bing-Yan Li
Summary: This study conducted a systematic review and meta-analysis, and found that higher daily intake of total fat, saturated fat, animal fat, and cholesterol, as well as higher levels of serum triglycerides, were significantly associated with an increased risk of ovarian cancer.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Walter Currenti, Justyna Godos, Amer M. Alanazi, Giuseppe Lanza, Raffaele Ferri, Filippo Caraci, Fabio Galvano, Sabrina Castellano, Giuseppe Grosso
Summary: This study investigated the relationship between the intake of different types of dietary fats and depressive symptoms in Italian individuals living in the Mediterranean area. The results showed a negative association between moderate intake of polyunsaturated fatty acids (PUFA) and depressive symptoms, while moderate intake of saturated fatty acids (SFA) was positively associated with depressive symptoms. Moreover, individuals with lower to moderate intake of short-chain and medium-chain saturated fatty acids had a lower risk of depressive symptoms. These findings highlight the importance of distinguishing between different fat types.
Article
Nutrition & Dietetics
Justyna Godos, Marialaura Bonaccio, Wahidah H. Al-Qahtani, Wolfgang Marx, Melissa M. Lane, Gian Marco Leggio, Giuseppe Grosso
Summary: This study aimed to investigate the relationship between consumption of ultra-processed foods (UPFs) and depressive symptoms in younger Italian adults. The results showed that individuals with higher UPF consumption had a higher likelihood of having depressive symptoms. This association remained significant even after adjusting for potential confounding factors, indicating a potential link between UPF consumption and depressive symptoms in younger Italian individuals.
Article
Biochemistry & Molecular Biology
Agnieszka Micek, Joanna Jurek, Marcin Owczarek, Ida Guerrera, Sebastiano Alfio Torrisi, Sabrina Castellano, Giuseppe Grosso, Ali A. Alshatwi, Justyna Godos
Summary: Emerging evidence suggests that diets rich in plant-based foods and beverages may have positive effects on human health in reducing the risk of chronic diseases. This study investigated the association between polyphenol-rich beverage intake and mental health outcomes among adults in the Mediterranean area. The results showed that moderate intake of coffee and tea was associated with lower perceived stress and depressive symptoms, while regular coffee and moderate/regular red wine drinkers were less likely to have depressive symptoms. However, no significant associations were found for the intake of these beverages and sleep quality.
Article
Geriatrics & Gerontology
Justyna Godos, Giuseppe Grosso, Raffaele Ferri, Filippo Caraci, Giuseppe Lanza, Wahidah H. Al-Qahtani, Giuseppe Caruso, Sabrina Castellano
Summary: Studies show that adhering to the Mediterranean diet is associated with better mental and cognitive health, quality of life, and successful aging in middle-age and older adults. The results of this study indicate that individuals who adhere to the Mediterranean diet are less likely to have cognitive impairment and depressive symptoms, and are more likely to have good quality of life, good sleep quality, and successful aging.
EXPERIMENTAL GERONTOLOGY
(2023)
Editorial Material
Neurosciences
Mariagiovanna Cantone, Giulio Geraci, Justyna Godos, Giuseppe Lanza
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Nutrition & Dietetics
Walter Currenti, Justyna Godos, Amer M. Alanazi, Giuseppe Lanza, Raffaele Ferri, Filippo Caraci, Giuseppe Grosso, Fabio Galvano, Sabrina Castellano
Summary: The increase in life expectancy has led to a higher prevalence of age-related neurological diseases, such as cognitive impairment, dementia, and Alzheimer's disease. This study aimed to examine the association between specific categories and subcategories of dietary fats and cognitive status in older Italian adults. The results showed that moderate consumption of certain types of saturated fatty acids and monounsaturated fatty acids was associated with a lower risk of cognitive impairment, while moderate intake of linoleic acid was associated with a higher risk of cognitive impairment.
Article
Biochemistry & Molecular Biology
Joanna Goralska, Urszula Razny, Anna Gruca, Anna Zdzienicka, Agnieszka Micek, Aldona Dembinska-Kiec, Bogdan Solnica, Malgorzata Malczewska-Malec
Summary: There is increasing interest in the non-invasive identification and monitoring of liver damage in obese patients. Plasma cytokeratin-18 (CK-18) fragment levels have been proposed to predict the presence of non-alcoholic steatohepatitis (NASH). This study aimed to analyze the associations of CK-18 with obesity and related complications. The findings suggest that CK-18 can distinguish between different metabolic phenotypes in obesity.
Article
Nutrition & Dietetics
Agnieszka Micek, Walter Currenti, Cristiana Mignogna, Alice Rosi, Ignazio Barbagallo, Ali A. Alshatwi, Daniele Del Rio, Pedro Mena, Justyna Godos
Summary: This study found that anthocyanins in 100% fruit juices may mediate the potential beneficial effects on blood lipids, with an increase in anthocyanins related to a decrease in total cholesterol and LDL cholesterol.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Chiara Peila, Lorenzo Riboldi, Elena Spada, Alessandra Coscia, Ignazio Barbagallo, Giovanni Li Volti, Fabio Galvano, Diego Gazzolo
Summary: The study aimed to evaluate the impact of preeclampsia and gestational diabetes mellitus on the redox homeostasis of human milk. The results showed that gestational diabetes mellitus may affect the glutathione level in breast milk.
Review
Biochemistry & Molecular Biology
Samuele Laudani, Justyna Godos, Federica Martina Di Domenico, Ignazio Barbagallo, Cinzia Lucia Randazzo, Gian Marco Leggio, Fabio Galvano, Giuseppe Grosso
Summary: Hypertension and cardiovascular disease are major global causes of death, and increased oxidative stress and inflammation are associated with endothelial dysfunction. Anthocyanins, with their antioxidant and cardioprotective effects, have garnered significant interest, but their detection in blood serum is limited due to metabolism by gut microbiota. This review summarizes the main findings from clinical studies on the cardioprotective effects of anthocyanins, as well as the role of gut microbiota in their metabolism, bioavailability, and impact on microbiota composition. Further research is needed to clarify which molecules and doses of anthocyanins offer vascular benefits, while considering the crucial role of the microbiota.
Article
Nutrition & Dietetics
Agnieszka Micek, Izabela Boleslawska, Pawel Jagielski, Kamil Konopka, Anna Waskiewicz, Anna Maria Witkowska, Juliusz Przyslawski, Justyna Godos
Summary: The study investigates the association between dietary intake of total polyphenols, lignans, and plant sterols and the abundance of immunomodulatory gut microbiota as well as the risk of developing COVID-19. The findings suggest that consuming these plant-based compounds may decrease the risk of contracting COVID-19.
FRONTIERS IN NUTRITION
(2023)