Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer

The BECN1 N-terminal domain is intrinsically disordered

(2016) Erinna F. Lee et al.   Autophagy

Mechanistic study of TRPM2-Ca2+-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition

(2016) Qian Wang et al.   Autophagy

Web-TCGA: an online platform for integrated analysis of molecular cancer data sets

(2016) Mario Deng et al.   BMC BIOINFORMATICS

Unraveling the roles of Atg4 proteases from autophagy modulation to targeted cancer therapy

(2016) Lan Zhang et al.   CANCER LETTERS

ADRB2 signaling promotes HCC progression and sorafenib resistance by inhibiting autophagic degradation of HIF1α

(2016) Fu-Quan Wu et al.   JOURNAL OF HEPATOLOGY

Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy

(2016) Bowen Ke et al.   MEDICINAL RESEARCH REVIEWS

ACTP: A webserver for predicting potential targets and relevant pathways of autophagy-modulating compounds

(2016) Tao Xie et al.   Oncotarget

MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals

(2015) Jia Yuan et al.   Autophagy

The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells

(2015) Yan-Ning Rui et al.   Autophagy

AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferation

(2015) Valentina Cianfanelli et al.   CELL CYCLE

Atg1 family kinases in autophagy initiation

(2015) Nobuo N. Noda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes

(2015) Rikke Kruse et al.   DIABETOLOGIA

Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming

(2015) Yasong Wu et al.   NATURE CELL BIOLOGY

Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

(2015) Leilei Fu et al.   Oncotarget

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer

(2015) Bo Liu et al.   Oncotarget

Identification of ULK1 as a novel biomarker involved in miR-4487 and miR-595 regulation in neuroblastoma SH-SY5Y cell autophagy

(2015) Yi Chen et al.   Scientific Reports

Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer

(2015) Silvia Pineda et al.   PLoS Genetics

Integration and comparison of different genomic data for outcome prediction in cancer

(2015) Hugo Gómez-Rueda et al.   BioData Mining

Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

(2015) Hao Tang et al.   EBioMedicine

BECN1 is involved in the initiation of mitophagy

(2014) Vinay Choubey et al.   Autophagy

Combining multidimensional genomic measurements for predicting cancer prognosis: observations from TCGA

(2014) Q. Zhao et al.   BRIEFINGS IN BIOINFORMATICS

Autophagic effect of programmed cell death 5 (PDCD5) after focal cerebral ischemic reperfusion injury in rats

(2014) Zhao Jiang et al.   NEUROSCIENCE LETTERS

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells

(2013) Soon Young Shin et al.   CARCINOGENESIS

The use of principal component analysis and discriminant analysis in differential sensing routines

(2013) Sara Stewart et al.   CHEMICAL SOCIETY REVIEWS

Deciphering the complex: Methodological overview of statistical models to derive OMICS-based biomarkers

(2013) Marc Chadeau-Hyam et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Beclin-1: Autophagic regulator and therapeutic target in cancer

(2013) Lei-lei Fu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Molecular Characterization of Basal-Like and Non-Basal-Like Triple-Negative Breast Cancer

(2013) A. Prat et al.   ONCOLOGIST

Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer

(2013) B Liu et al.   Cell Death & Disease

Integrating Genetic Association, Genetics of Gene Expression, and Single Nucleotide Polymorphism Set Analysis to Identify Susceptibility Loci for Type 2 Diabetes Mellitus

(2012) D. M. Greenawalt et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

XBP1mRNA Splicing Triggers an Autophagic Response in Endothelial Cells throughBECLIN-1Transcriptional Activation

(2012) Andriana Margariti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regression shrinkage and selection via the lasso: a retrospective

(2011) Robert Tibshirani   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events

(2010) Reza R. Serizawa et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

(2010) Chan Gao et al.   NATURE CELL BIOLOGY

Simultaneous analysis of distinct Omics data sets with integration of biological knowledge: Multiple Factor Analysis approach.

(2009) Marie de Tayrac et al.   BMC GENOMICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols