MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility

Visualizing microtubule structural transitions and interactions with associated proteins

(2016) Eva Nogales et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins

(2016) Linda Wordeman et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

(2016) Alberto Elosegui-Artola et al.   NATURE CELL BIOLOGY

Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks

(2015) Shawn P. Carey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen

(2015) Ingo Thievessen et al.   FASEB JOURNAL

Rho family GTPases: Making it to the third dimension

(2015) Kristin M. Riching et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Writing and Reading the Tubulin Code

(2015) Ian Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature

(2015) Hunter Elliott et al.   NATURE CELL BIOLOGY

Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

Fibroblasts Lead the Way: A Unified View of 3D Cell Motility

(2015) Ryan J. Petrie et al.   TRENDS IN CELL BIOLOGY

Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions

(2015) Andrew D. Doyle et al.   Nature Communications

Cell-generated traction forces and the resulting matrix deformation modulate microvascular alignment and growth during angiogenesis

(2014) Clayton J. Underwood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

3D Traction Stresses Activate Protease-Dependent Invasion of Cancer Cells

(2014) Aereas Aung et al.   BIOPHYSICAL JOURNAL

Mechanical Interaction of Angiogenic Microvessels With the Extracellular Matrix

(2014) Lowell T. Edgar et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells

(2014) Alexander Braun et al.   JOURNAL OF CELL BIOLOGY

Extracellular Matrix Density Regulates the Rate of Neovessel Growth and Branching in Sprouting Angiogenesis

(2014) Lowell T. Edgar et al.   PLoS One

A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling

(2014) Y. H. Bae et al.   Science Signaling

Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior

(2012) Robert S Fischer et al.   Nature Protocols

Depolymerizing Kinesins Kip3 and MCAK Shape Cellular Microtubule Architecture by Differential Control of Catastrophe

(2011) Melissa K. Gardner et al.   CELL

The C-termini of tubulin and the specific geometry of tubulin substrates influence the depolymerization activity of MCAK

(2011) Kathleen M. Hertzer et al.   CELL CYCLE

Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis

(2011) Kenneth A. Myers et al.   JOURNAL OF CELL BIOLOGY

Mechanical forces-induced human osteoblasts differentiation involves MMP-2/MMP-13/MT1-MMP proteolytic cascade

(2011) Stéphane Barthelemi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics

(2011) Kathryn T. Applegate et al.   JOURNAL OF STRUCTURAL BIOLOGY

Collagen oligomers modulate physical and biological properties of three-dimensional self-assembled matrices

(2010) J. L. Bailey et al.   BIOPOLYMERS

In Vitro Reconstitution of the Functional Interplay between MCAK and EB3 at Microtubule Plus Ends

(2010) Susana Montenegro Gouveia et al.   CURRENT BIOLOGY

Mechanics of cell spreading within 3D-micropatterned environments

(2010) Marion Ghibaudo et al.   LAB ON A CHIP

Analysis of microtubule dynamic instability using a plus-end growth marker

(2010) Alexandre Matov et al.   NATURE METHODS

Endothelial cell traction and ECM density influence both capillary morphogenesis and maintenance in 3-D

(2009) Ekaterina Kniazeva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ICIS and Aurora B Coregulate the Microtubule Depolymerase Kif2a

(2009) Anne L. Knowlton et al.   CURRENT BIOLOGY

Local Cortical Tension by Myosin II Guides 3D Endothelial Cell Branching

(2009) Robert S. Fischer et al.   CURRENT BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Aurora A Phosphorylates MCAK to Control Ran-dependent Spindle Bipolarity

(2008) Xin Zhang et al.   MOLECULAR BIOLOGY OF THE CELL