Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes

Quantitative proteomic characterization of redox-dependent post-translational modifications on protein cysteines

(2017) Jicheng Duan et al.   Molecular BioSystems

Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress

(2017) Nathan P Westcott et al.   Nature Chemical Biology

Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

(2017) Takao Fujisawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lifespan Control by Redox-Dependent Recruitment of Chaperones to Misfolded Proteins

(2016) Sarah Hanzén et al.   CELL

Optimization of Caged Electrophiles for Improved Monitoring of Cysteine Reactivity in Living Cells

(2016) Masahiro Abo et al.   CHEMBIOCHEM

Proteome-wide covalent ligand discovery in native biological systems

(2016) Keriann M. Backus et al.   NATURE

2016 update of the PRIDE database and its related tools

(2016) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Peroxiredoxin Catalysis at Atomic Resolution

(2016) Arden Perkins et al.   STRUCTURE

Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-Dependent Regulation of Macrophage Function during Nanoparticle-Induced Oxidative Stress

(2015) Jicheng Duan et al.   ACS Nano

Quantitative Chemoproteomics for Site-Specific Analysis of Protein Alkylation by 4-Hydroxy-2-Nonenal in Cells

(2015) Jing Yang et al.   ANALYTICAL CHEMISTRY

Mapping Proteome-Wide Targets of Environmental Chemicals Using Reactivity-Based Chemoproteomic Platforms

(2015) Daniel Medina-Cleghorn et al.   CHEMISTRY & BIOLOGY

A Caged Electrophilic Probe for Global Analysis of Cysteine Reactivity in Living Cells

(2015) Masahiro Abo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Expanding Landscape of the Thiol Redox Proteome

(2015) Jing Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

A proton relay enhances H2O2 sensitivity of GAPDH to facilitate metabolic adaptation

(2015) David Peralta et al.   Nature Chemical Biology

Avoiding abundance bias in the functional annotation of posttranslationally modified proteins

(2015) Christian Schölz et al.   NATURE METHODS

Global, in situ, site-specific analysis of protein S-sulfenylation

(2015) Jing Yang et al.   Nature Protocols

eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences

(2015) Jaime Huerta-Cepas et al.   NUCLEIC ACIDS RESEARCH

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Steady-State Hydrogen Peroxide Induces Glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa

(2014) X. Deng et al.   JOURNAL OF BACTERIOLOGY

The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity

(2014) David Medgyesi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteome-wide Light/Dark Modulation of Thiol Oxidation in Cyanobacteria Revealed by Quantitative Site-specific Redox Proteomics

(2014) Jia Guo et al.   MOLECULAR & CELLULAR PROTEOMICS

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mapping the diatom redox-sensitive proteome provides insight into response to nitrogen stress in the marine environment

(2014) S. Rosenwasser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thiol-based regulation of glyceraldehyde-3-phosphate dehydrogenase in blood bank-stored red blood cells: a strategy to counteract oxidative stress

(2014) Sara Rinalducci et al.   TRANSFUSION

Site-specific mapping and quantification of protein S-sulphenylation in cells

(2014) Jing Yang et al.   Nature Communications

MS-GF+ makes progress towards a universal database search tool for proteomics

(2014) Sangtae Kim et al.   Nature Communications

Proteome-wide Quantification and Characterization of Oxidation-Sensitive Cysteines in Pathogenic Bacteria

(2013) Xin Deng et al.   Cell Host & Microbe

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids

(2013) Julie A. Reisz et al.   FEBS Journal

Proteomic identification and quantification of S-glutathionylation in mouse macrophages using resin-assisted enrichment and isobaric labeling

(2013) Dian Su et al.   FREE RADICAL BIOLOGY AND MEDICINE

pLogo: a probabilistic approach to visualizing sequence motifs

(2013) Joseph P O'Shea et al.   NATURE METHODS

A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles

(2013) Chu Wang et al.   NATURE METHODS

Resin-assisted enrichment of thiols as a general strategy for proteomic profiling of cysteine-based reversible modifications

(2013) Jia Guo et al.   Nature Protocols

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

(2013) Yogesh Kulathu et al.   Nature Communications

Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells

(2013) Jin-Gu Lee et al.   Nature Communications

Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline

(2012) Birgit Schilling et al.   MOLECULAR & CELLULAR PROTEOMICS

A cross-platform toolkit for mass spectrometry and proteomics

(2012) Matthew C Chambers et al.   NATURE BIOTECHNOLOGY

Deubiquitinases as a Signaling Target of Oxidative Stress

(2012) Xiomaris M. Cotto-Rios et al.   Cell Reports

Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

(2011) Robert Karisch et al.   CELL

Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis

(2011) Joseph R. Burgoyne et al.   FASEB JOURNAL

A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism

(2011) Péricles Arruda Mitozo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle

(2011) Zhenbo Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Protein Expression Regulation under Oxidative Stress

(2011) Christine Vogel et al.   MOLECULAR & CELLULAR PROTEOMICS

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Graphical analysis of pH-dependent properties of proteins predicted using PROPKA

(2011) Michał Rostkowski et al.   BMC STRUCTURAL BIOLOGY

Quantitative reactivity profiling predicts functional cysteines in proteomes

(2010) Eranthie Weerapana et al.   NATURE

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Regulation of the 26S Proteasome Complex During Oxidative Stress

(2010) X. Wang et al.   Science Signaling

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity

(2009) Tobias B Dansen et al.   Nature Chemical Biology

Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation

(2009) D. J. Kemble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversibility of Covalent Electrophile−Protein Adducts and Chemical Toxicity

(2008) De Lin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure of the sulphiredoxin–peroxiredoxin complex reveals an essential repair embrace

(2008) Thomas J. Jönsson et al.   NATURE

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology