The Combined Influence of Hydrogel Stiffness and Matrix-Bound Hyaluronic Acid Content on Glioblastoma Invasion

Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance

(2016) M. A. Miller et al.   Cancer Discovery

Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes

(2016) Chris L. Smith et al.   Cell Reports

The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogel

(2015) Bhushan P. Mahadik et al.   BIOMATERIALS

Extracellular Matrix Properties Regulate the Migratory Response of Glioblastoma Stem Cells in Three-Dimensional Culture

(2015) Marisol Herrera-Perez et al.   TISSUE ENGINEERING PART A

Microfluidic Strategies for Understanding the Mechanics of Cells and Cell-Mimetic Systems

(2015) Joanna B. Dahl et al.   Annual Review of Chemical and Biomolecular Engineering

Substrate stress relaxation regulates cell spreading

(2015) Ovijit Chaudhuri et al.   Nature Communications

Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering

(2015) Steven R. Caliari et al.   Advanced Healthcare Materials

Hyaluronan – A Functional and Structural Sweet Spot in the Tissue Microenvironment

(2015) James Monslow et al.   Frontiers in Immunology

Engineering strategies to mimic the glioblastoma microenvironment

(2014) Andrew Rape et al.   ADVANCED DRUG DELIVERY REVIEWS

Spatially Gradated Hydrogel Platform as a 3D Engineered Tumor Microenvironment

(2014) Sara Pedron et al.   ADVANCED MATERIALS

Bioengineered Scaffolds for 3D Analysis of Glioblastoma Proliferation and Invasion

(2014) John M. Heffernan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

A three-dimensional in vitro model of tumor cell intravasation

(2014) Seema M. Ehsan et al.   Integrative Biology

CD44-Mediated Adhesion to Hyaluronic Acid Contributes to Mechanosensing and Invasive Motility

(2014) Yushan Kim et al.   MOLECULAR CANCER RESEARCH

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

Microenvironmental Stiffness Enhances Glioma Cell Proliferation by Stimulating Epidermal Growth Factor Receptor Signaling

(2014) Vaibhavi Umesh et al.   PLoS One

Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells

(2014) Stacey Watkins et al.   Nature Communications

Design of cell–matrix interactions in hyaluronic acid hydrogel scaffolds

(2013) Jonathan Lam et al.   Acta Biomaterialia

Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid

(2013) Sara Pedron et al.   BIOMATERIALS

Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening

(2013) Carine Jiguet Jiglaire et al.   EXPERIMENTAL CELL RESEARCH

Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy

(2013) S. Pedron et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Fibronectin expression in glioblastomas promotes cell cohesion, collective invasion of basement membrane in vitro and orthotopic tumor growth in mice

(2013) E Serres et al.   ONCOGENE

Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis

(2013) L. Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Concise Review: The Evolution of human pluripotent stem cell culture: From feeder cells to synthetic coatings

(2012) L.G. Villa-Diaz et al.   STEM CELLS

Smart Nanocarrier Based on PEGylated Hyaluronic Acid for Cancer Therapy

(2011) Ki Young Choi et al.   ACS Nano

In vitro generation of osteochondral differentiation of human marrow mesenchymal stem cells in novel collagen–hydroxyapatite layered scaffolds

(2011) Jiaan Zhou et al.   Acta Biomaterialia

Lost in disruption: Role of proteases in glioma invasion and progression

(2011) Rolf Mentlein et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Influence of chondroitin sulfate and hyaluronic acid on structure, mechanical properties, and glioma invasion of collagen I gels

(2011) Ya-li Yang et al.   BIOMATERIALS

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

3D in vitro bioengineered tumors based on collagen I hydrogels

(2011) Christopher S. Szot et al.   BIOMATERIALS

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

(2011) M. Ehrbar et al.   BIOPHYSICAL JOURNAL

Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties

(2011) Jennifer C. Rodrigues et al.   NEURO-ONCOLOGY

PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

(2011) V Serra et al.   ONCOGENE

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

(2011) J. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of hyaluronidases in colorectal cancer

(2010) Helen Bouga et al.   BMC CANCER

CD44 Attenuates Activation of the Hippo Signaling Pathway and Is a Prime Therapeutic Target for Glioblastoma

(2010) Y. Xu et al.   CANCER RESEARCH

Isolation and characterization of cancer stem like cells in human glioblastoma cell lines

(2009) Lei Qiang et al.   CANCER LETTERS

A Novel Splice Variant of GLI1 That Promotes Glioblastoma Cell Migration and Invasion

(2009) H.-W. Lo et al.   CANCER RESEARCH

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL

(2009) L. Liu et al.   CANCER RESEARCH

Modulation of hyaluronan production by CD44 positive glioma cells

(2009) Marzenna Wiranowska et al.   INTERNATIONAL JOURNAL OF CANCER

Microarchitecture of Three-Dimensional Scaffolds Influences Cell Migration Behavior via Junction Interactions

(2008) Brendan A.C. Harley et al.   BIOPHYSICAL JOURNAL

Epidermal Growth Factor–induced Enhancement of Glioblastoma Cell Migration in 3D Arises from an Intrinsic Increase in Speed But an Extrinsic Matrix- and Proteolysis-dependent Increase in Persistence

(2008) Hyung-Do Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Magnetic resonance elastography of the brain

(2007) Scott A. Kruse et al.   NEUROIMAGE