Nonspecificity in a nonimmune human scFv repertoire

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes

(2016) Nicole L. Kallewaard et al.   CELL

Use of the VH6-1 gene segment to code for anti-interleukin-18 autoantibodies in multiple sclerosis

(2016) Marina Tiumentseva et al.   IMMUNOGENETICS

Improved prediction of antibody VL–VHorientation

(2016) Nicholas A. Marze et al.   PROTEIN ENGINEERING DESIGN & SELECTION

High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice

(2015) Ryan L Kelly et al.   mAbs

The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies

(2015) Amita Datta-Mannan et al.   mAbs

Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

(2015) Amita Datta-Mannan et al.   mAbs

Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy

(2014) Anthony P. West et al.   CELL

A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties

(2013) Thomas Tiller et al.   mAbs

Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)

(2013) Sergey Lyskov et al.   PLoS One

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

(2013) Y. Xu et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A strategy for risk mitigation of antibodies with fast clearance

(2012) Isidro Hötzel et al.   mAbs

Polyreactive antibodies in adaptive immune responses to viruses

(2011) Hugo Mouquet et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HuCAL PLATINUM, a Synthetic Fab Library Optimized for Sequence Diversity and Superior Performance in Mammalian Expression Systems

(2011) Josef Prassler et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of Charge on Antibody Tissue Distribution and Pharmacokinetics

(2010) C. Andrew Boswell et al.   BIOCONJUGATE CHEMISTRY

The functional capacity of the natural amino acids for molecular recognition

(2010) Sara Birtalan et al.   Molecular BioSystems

RosettaAntibody: antibody variable region homology modeling server

(2009) A. Sircar et al.   NUCLEIC ACIDS RESEARCH

The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies

(2008) Sara Birtalan et al.   JOURNAL OF MOLECULAR BIOLOGY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

Toward high-resolution homology modeling of antibody Fvregions and application to antibody-antigen docking

(2008) Arvind Sivasubramanian et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS