A novel AHI-1–BCR-ABL–DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy
出版年份 2017 全文链接
标题
A novel AHI-1–BCR-ABL–DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy
作者
关键词
-
出版物
LEUKEMIA
Volume 31, Issue 11, Pages 2376-2387
出版商
Springer Nature
发表日期
2017-04-03
DOI
10.1038/leu.2017.108
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs
- (2016) Yoshinori Takahashi et al. Oncotarget
- A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies
- (2015) Mary E. Irwin et al. Oncotarget
- Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy
- (2015) Laura Poillet-Perez et al. Redox Biology
- The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells
- (2014) K. Rothe et al. BLOOD
- Control of MT1-MMP transport by atypical PKC during breast-cancer progression
- (2014) C. Rosse et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endocytosis and Autophagy: Exploitation or Cooperation?
- (2014) S. A. Tooze et al. Cold Spring Harbor Perspectives in Biology
- The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
- (2014) Mónika Lippai et al. Biomed Research International
- European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
- (2013) M. Baccarani et al. BLOOD
- Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt- -catenin signaling
- (2013) B. Zhang et al. BLOOD
- Autophagy regulation by nutrient signaling
- (2013) Ryan C Russell et al. CELL RESEARCH
- Dynamin 2 Potentiates Invasive Migration of Pancreatic Tumor Cells through Stabilization of the Rac1 GEF Vav1
- (2013) Gina L. Razidlo et al. DEVELOPMENTAL CELL
- Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes
- (2013) Ryan J. Schulze et al. JOURNAL OF CELL BIOLOGY
- Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex
- (2013) Min Chen et al. JNCI-Journal of the National Cancer Institute
- Endocytosis and Cancer
- (2013) I. Mellman et al. Cold Spring Harbor Perspectives in Biology
- Dynamin-2 Function and Dysfunction Along the Secretory Pathway
- (2013) Arlek M. González-Jamett et al. Frontiers in Endocrinology
- Beclin1: A role in membrane dynamics and beyond
- (2012) Ellen Wirawan et al. Autophagy
- Endocytosis and autophagy: Shared machinery for degradation
- (2012) Christopher A. Lamb et al. BIOESSAYS
- The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
- (2012) Jinghui Zhang et al. NATURE
- Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL+chronic myeloid leukemia cells to tyrosine kinase inhibitors
- (2012) Xiaohu Liu et al. PROTEOMICS
- Genomic Instability in Chronic Myeloid Leukemia: Targets for Therapy?
- (2012) N. Muvarak et al. Current Hematologic Malignancy Reports
- The interplay between autophagy and ROS in tumorigenesis
- (2012) Sameera Kongara et al. Frontiers in Oncology
- BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription
- (2011) Z. Sheng et al. BLOOD
- Imatinib induces autophagy throughBECLIN‐1andATG5genes in chronic myeloid leukemia cells
- (2011) Geylani Can et al. Hematology
- Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma
- (2011) R D Eppinga et al. ONCOGENE
- Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
- (2011) H Feng et al. ONCOGENE
- Dynamin 2 Associates with Microtubules at Mitosis and Regulates Cell Cycle Progression
- (2010) Nobuhisa Ishida et al. CELL STRUCTURE AND FUNCTION
- Direct dynamin–actin interactions regulate the actin cytoskeleton
- (2010) Changkyu Gu et al. EMBO JOURNAL
- A centronuclear myopathy-dynamin 2 mutation impairs skeletal muscle structure and function in mice
- (2010) Anne-Cécile Durieux et al. HUMAN MOLECULAR GENETICS
- Chronic myeloid leukemia: mechanisms of blastic transformation
- (2010) Danilo Perrotti et al. JOURNAL OF CLINICAL INVESTIGATION
- Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
- (2010) Amie S. Corbin et al. JOURNAL OF CLINICAL INVESTIGATION
- Dynamin 2 and human diseases
- (2010) Anne-Cécile Durieux et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial
- (2010) François-Xavier Mahon et al. LANCET ONCOLOGY
- Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR
- (2010) D M Ross et al. LEUKEMIA
- A fluorescence-based in vitro assay for investigating early endosome dynamics
- (2010) Sina V Barysch et al. Nature Protocols
- Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis
- (2010) B J Altman et al. ONCOGENE
- AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
- (2009) Thomas O'Hare et al. CANCER CELL
- Dynamin 2 and c-Abl Are Novel Regulators of Hyperoxia-mediated NADPH Oxidase Activation and Reactive Oxygen Species Production in Caveolin-enriched Microdomains of the Endothelium
- (2009) Patrick A. Singleton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway
- (2009) R Naughton et al. LEUKEMIA
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- Endocytosis, signaling and cancer, much more than meets the eye
- (2009) Pier Paolo Di Fiore Molecular Oncology
- Charting the molecular network of the drug target Bcr-Abl
- (2009) M. Brehme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Approach to the Management of Chronic Myeloid Leukemia in British Columbia
- (2008) Donna Lynn Forrest et al. Current Oncology
- AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells
- (2008) Liang L. Zhou et al. JOURNAL OF EXPERIMENTAL MEDICINE
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