A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice

Glomerular cell crosstalk

(2016) Rachel Lennon et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Activation of general control nonderepressible 2 kinase protects human glomerular endothelial cells from harmful high-glucose-induced molecular pathways

(2016) Theodoros Eleftheriadis et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Diabetic nephropathy and endothelial dysfunction: Current and future therapies, and emerging of vascular imaging for preclinical renal-kinetic study

(2016) Wilson KC Leung et al.   LIFE SCIENCES

Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening

(2016) Martijn J. Wilmer et al.   TRENDS IN BIOTECHNOLOGY

Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms

(2016) Luigi Gnudi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease

(2016) Alejandra Guillermina Miranda-Díaz et al.   Journal of Diabetes Research

Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis

(2015) Olivia Lenoir et al.   Autophagy

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Interleukin-1β increases permeability and upregulates the expression of vascular endothelial-cadherin in human renal glomerular endothelial cells

(2015) LINNA DU et al.   Molecular Medicine Reports

Spironolactone inhibits podocyte motility via decreasing integrin β1 and increasing integrin β3 in podocytes under high-glucose conditions

(2015) ZHUO LI et al.   Molecular Medicine Reports

Organotypic brain slice cultures: A review

(2015) C. Humpel   NEUROSCIENCE

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy

(2015) Hui Xu et al.   Oncotarget

Microfluidic Organ-on-a-Chip Technology for Advancement of Drug Development and Toxicology

(2015) Jeremy D. Caplin et al.   Advanced Healthcare Materials

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Molecular and Cellular Events Mediating Glomerular Podocyte Dysfunction and Depletion in Diabetes Mellitus

(2014) P. Anil Kumar et al.   Frontiers in Endocrinology

Scaling and systems biology for integrating multiple organs-on-a-chip

(2013) John P. Wikswo et al.   LAB ON A CHIP

Workshop meeting report Organs-on-Chips: human disease models

(2013) Anja van de Stolpe et al.   LAB ON A CHIP

Simvastatin Alleviates Hyperpermeability of Glomerular Endothelial Cells in Early-Stage Diabetic Nephropathy by Inhibition of RhoA/ROCK1

(2013) Hui Peng et al.   PLoS One

Hyperglycemia Causes Renal Cell Damage via CCN2-Induced Activation of the TrkA Receptor: Implications for Diabetic Nephropathy

(2012) M. Fragiadaki et al.   DIABETES

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues

(2012) Yu Huang et al.   LAB ON A CHIP

Role of the Podocyte (and Glomerular Endothelium) in Building the GBM

(2012) Dale R. Abrahamson   SEMINARS IN NEPHROLOGY

A microfluidic device for tissue biopsy culture and interrogation

(2010) Abigail Webster et al.   Analytical Methods

Fluid-shear-stress-induced translocation of aquaporin-2 and reorganization of actin cytoskeleton in renal tubular epithelial cells

(2010) Kyung-Jin Jang et al.   Integrative Biology

Inhibition of integrin-linked kinase blocks podocyte epithelial–mesenchymal transition and ameliorates proteinuria

(2010) Young Sun Kang et al.   KIDNEY INTERNATIONAL

Microfluidic perfusion system for maintaining viable heart tissue with real-time electrochemical monitoring of reactive oxygen species

(2010) Lih-Tyng Cheah et al.   LAB ON A CHIP

Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1

(2009) R. Lennon et al.   DIABETOLOGIA

Culturing thick brain slices: An interstitial 3D microperfusion system for enhanced viability

(2009) Komal Rambani et al.   JOURNAL OF NEUROSCIENCE METHODS

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells

(2009) Kyung-Jin Jang et al.   LAB ON A CHIP

Development of a microfluidic device for the maintenance and interrogation of viable tissue biopsies

(2008) Samantha M. Hattersley et al.   LAB ON A CHIP