Liver-targeting self-assembled hyaluronic acid-glycyrrhetinic acid micelles enhance hepato-protective effect of silybin after oral administration

In vivopharmacokinetics, biodistribution and antitumor effect of paclitaxel-loaded micelles based onα-tocopherol succinate-modified chitosan

(2015) Na Liang et al.   DRUG DELIVERY

Co-delivery of baicalein and doxorubicin by hyaluronic acid decorated nanostructured lipid carriers for breast cancer therapy

(2015) Qian Liu et al.   DRUG DELIVERY

Biological evaluation of redox-sensitive micelles based on hyaluronic acid-deoxycholic acid conjugates for tumor-specific delivery of paclitaxel

(2015) Jing Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer

(2014) Hee Kyung Ahn et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Development, optimization and characterization of glycyrrhetinic acid–chitosan nanoparticles of atorvastatin for liver targeting

(2014) Raman Rohilla et al.   DRUG DELIVERY

Herbal and polymeric approaches for liver-targeting drug delivery: novel strategies and their significance

(2014) Raman Rohilla et al.   DRUG DELIVERY

In vivopharmacokinetics, biodistribution and anti-tumor effect of paclitaxel-loaded targeted chitosan-based polymeric micelle

(2014) Mahboubeh Rezazadeh et al.   DRUG DELIVERY

Phyto-liposomes as nanoshuttles for water-insoluble silybin–phospholipid complex

(2014) Ruggero Angelico et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of Salvianolic acid B–Tanshinone II A–Glycyrrhetinic acid compound liposomes: Formulation optimization and its effects on proliferation of hepatic stellate cells

(2014) Jiahao Lin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Chemical Modification of Hyaluronic Acid for Intraoral Application

(2014) Flavia Laffleur et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Inhibition of SIRT1 Signaling Sensitizes the Antitumor Activity of Silybin against Human Lung Adenocarcinoma Cells In Vitro and In Vivo

(2014) Z. Liang et al.   MOLECULAR CANCER THERAPEUTICS

Amine-modified hyaluronic acid-functionalized porous silicon nanoparticles for targeting breast cancer tumors

(2014) Patrick V. Almeida et al.   Nanoscale

Recent Advances in the Nanotechnology-Based Drug Delivery of Silybin

(2013) Yancai Wang et al.   Journal of Biomedical Nanotechnology

Enhanced Oral Delivery of Paclitaxel Using Acetylcysteine Functionalized Chitosan-Vitamin E Succinate Nanomicelles Based on a Mucus Bioadhesion and Penetration Mechanism

(2013) He Lian et al.   MOLECULAR PHARMACEUTICS

Silybin-Mediated Inhibition of Notch Signaling Exerts Antitumor Activity in Human Hepatocellular Carcinoma Cells

(2013) Song Zhang et al.   PLoS One

Oral drug delivery systems using chemical conjugates or physical complexes

(2012) Taslim A. Al-Hilal et al.   ADVANCED DRUG DELIVERY REVIEWS

Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: Preparation, in vitro and in vivo evaluation

(2012) Fatima Zohra Dahmani et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Seventy-two-hour release formulation of the poorly soluble drug silybin based on porous silica nanoparticles: In vitro release kinetics and in vitro/in vivo correlations in beagle dogs

(2012) Xia Cao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Glycyrrhetinic acid-graft-hyaluronic acid conjugate as a carrier for synergistic targeted delivery of antitumor drugs

(2012) Li Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In Vivo Evaluation of Silybin Nanosuspensions Targeting Liver

(2012) Yancai Wang et al.   Journal of Biomedical Nanotechnology

Physicochemical Conjugation with Deoxycholic Acid and Dimethylsulfoxide for Heparin Oral Delivery

(2011) Sang Kyoon Kim et al.   BIOCONJUGATE CHEMISTRY

Doxorubicin-loaded glycyrrhetinic acid-modified alginate nanoparticles for liver tumor chemotherapy

(2011) Chuangnian Zhang et al.   BIOMATERIALS

Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel

(2011) Jing Li et al.   BIOMATERIALS

Octreotide-Modified N-Octyl-O, N-Carboxymethyl Chitosan Micelles as Potential Carriers for Targeted Antitumor Drug Delivery

(2011) Aifeng Zou et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nanocarriers: A General Strategy for Enhancement of Oral Bioavailability of Poorly Absorbed or Pre-Systemically Metabolized Drugs

(2010) Zheng Cai et al.   CURRENT DRUG METABOLISM

Evaluation of polyanion-coated biodegradable polymeric micelles as drug delivery vehicles

(2010) Yuichi Ohya et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced Oral Absorption of Paclitaxel in N-Deoxycholic Acid-N, O-Hydroxyethyl Chitosan Micellar System

(2010) Hong Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Milk thistle in liver diseases: past, present, future

(2010) Ludovico Abenavoli et al.   PHYTOTHERAPY RESEARCH

Self-assembled hyaluronic acid nanoparticles for active tumor targeting

(2009) Ki Young Choi et al.   BIOMATERIALS

Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives

(2009) Eun Ju Oh et al.   JOURNAL OF CONTROLLED RELEASE

Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells

(2009) Marco Trappoliere et al.   JOURNAL OF HEPATOLOGY

Multitargeted therapy of cancer by silymarin

(2008) Kumaraguruparan Ramasamy et al.   CANCER LETTERS

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS