Silybin-Mediated Inhibition of Notch Signaling Exerts Antitumor Activity in Human Hepatocellular Carcinoma Cells

Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice

(2013) Min Zhao et al.   CANCER LETTERS

The Notch signaling pathway as a mediator of tumor survival

(2013) K. M. Capaccione et al.   CARCINOGENESIS

SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells

(2013) Yedong Cheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Notchl and Notch4 are markers for poor prognosis of hepatocellular carcinoma

(2013) Soomin Ahn et al.   Hepatobiliary & Pancreatic Diseases International

Fucoidan Derived from Undaria pinnatifida Induces Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells via the ROS-Mediated Mitochondrial Pathway

(2013) Lili Yang et al.   Marine Drugs

Multitargeting and Antimetastatic Potentials of Silibinin in Human HepG-2 and PLC/PRF/5 Hepatoma Cells

(2013) Reza Ghasemi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Pterostilbene Exerts Antitumor Activity via the Notch1 Signaling Pathway in Human Lung Adenocarcinoma Cells

(2013) Yang Yang et al.   PLoS One

Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway

(2013) Yanwu Liu et al.   TOXICOLOGY

Cadmium telluride quantum dots cause oxidative stress leading to extrinsic and intrinsic apoptosis in hepatocellular carcinoma HepG2 cells

(2013) Kathy C. Nguyen et al.   TOXICOLOGY

The Down-Regulation of Notch1 Inhibits the Invasion and Migration of Hepatocellular Carcinoma Cells by Inactivating the Cyclooxygenase-2/Snail/E-cadherin Pathway In Vitro

(2012) Liang Zhou et al.   DIGESTIVE DISEASES AND SCIENCES

Constitutive Notch2 signaling induces hepatic tumors in mice

(2012) Michael T. Dill et al.   HEPATOLOGY

Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling

(2012) Gagan Deep et al.   PLoS One

Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy

(2012) S. M. McAuliffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alantolactone Induces Apoptosis in HepG2 Cells through GSH Depletion, Inhibition of STAT3 Activation, and Mitochondrial Dysfunction

(2012) Muhammad Khan et al.   Biomed Research International

Notch-1 signaling facilitates survivin expression in human non-small cell lung cancer cells

(2011) Yuqing Chen et al.   CANCER BIOLOGY & THERAPY

Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma

(2011) Weijie Guo et al.   CANCER LETTERS

Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel

(2011) Horng-Rong Chang et al.   MOLECULAR CARCINOGENESIS

Effect of silibinin in human colorectal cancer cells: Targeting the activation of NF-κB signaling

(2011) Komal Raina et al.   MOLECULAR CARCINOGENESIS

Synergistic Effects of Arsenic Trioxide and Silibinin on Apoptosis and Invasion in Human Glioblastoma U87MG Cell Line

(2011) Majid Zaki Dizaji et al.   NEUROCHEMICAL RESEARCH

Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer

(2010) Gagan Deep et al.   CANCER AND METASTASIS REVIEWS

 -Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

(2009) R. D. Meng et al.   CANCER RESEARCH

Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling

(2009) R. P. Singh et al.   CLINICAL CANCER RESEARCH

RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells

(2009) Juan Gao et al.   EXPERIMENTAL CELL RESEARCH

Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticles

(2009) Elodie Ristorcelli et al.   INTERNATIONAL JOURNAL OF CANCER

Evaluation of the genotoxic and anti-genotoxic activities of Silybin in human hepatoma cells (HepG2)

(2009) J. P. F. Angeli et al.   MUTAGENESIS