2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex

Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey

(2016) P.H. Gobira et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Effects of intra-infralimbic prefrontal cortex injections of cannabidiol in the modulation of emotional behaviors in rats: Contribution of 5HT1A receptors and stressful experiences

(2015) A.L.Z. Marinho et al.   BEHAVIOURAL BRAIN RESEARCH

2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons

(2015) Alvaro Llorente-Berzal et al.   PSYCHOPHARMACOLOGY

The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear

(2015) Thomas F. Giustino et al.   Frontiers in Behavioral Neuroscience

Transgenic Increase in n-3/n-6 Fatty Acid Ratio Protects Against Cognitive Deficits Induced by an Immune Challenge through Decrease of Neuroinflammation

(2014) Jean-Christophe Delpech et al.   NEUROPSYCHOPHARMACOLOGY

A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior

(2014) Ryan J. McLaughlin et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Genetic Disruption of 2-Arachidonoylglycerol Synthesis Reveals a Key Role for Endocannabinoid Signaling in Anxiety Modulation

(2014) Brian C. Shonesy et al.   Cell Reports

Modulation of anxiety-like behavior by the endocannabinoid 2-arachidonoylglycerol (2-AG) in the dorsolateral periaqueductal gray

(2013) A.F. Almeida-Santos et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: Involvement of 5HT1A receptors and previous stressful experience

(2013) M.V. Fogaça et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

More surprises lying ahead. The endocannabinoids keep us guessing

(2013) Daniele Piomelli   NEUROPHARMACOLOGY

The temporal dynamics of the effects of monoacylglycerol lipase blockade on locomotion, anxiety, and body temperature

(2012) Mano Aliczki et al.   BEHAVIOURAL PHARMACOLOGY

Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-  Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia

(2012) L. C. Gregg et al.   JOURNAL OF NEUROSCIENCE

The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior

(2012) Manoela V. Fogaça et al.   NEUROPHARMACOLOGY

High Times for Low-Frequency Stimulation as Endocannabinoids Engage in Hippocampal Long-Term Depression

(2012) Sachin Patel   NEUROPSYCHOPHARMACOLOGY

Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats

(2012) Manoela V. Fogaça et al.   PSYCHOPHARMACOLOGY

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Differential Role of Anandamide and 2-Arachidonoylglycerol in Memory and Anxiety-like Responses

(2011) Arnau Busquets-Garcia et al.   BIOLOGICAL PSYCHIATRY

Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition

(2011) H-T Liao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recruitment of Prefrontal Cortical Endocannabinoid Signaling by Glucocorticoids Contributes to Termination of the Stress Response

(2011) M. N. Hill et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic diacylglycerol lipase α mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex

(2011) Hiroki Yoshino et al.   JOURNAL OF PHYSIOLOGY-LONDON

NMDA Receptors, mGluR5 and Endocannabinoids are Involved in a Cascade Leading to Hippocampal Long-Term Depression

(2011) Yukitoshi Izumi et al.   NEUROPSYCHOPHARMACOLOGY

Opposing Roles for Cannabinoid Receptor Type-1 (CB1) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats

(2011) Plínio C Casarotto et al.   NEUROPSYCHOPHARMACOLOGY

Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety—two sides of one coin?

(2011) F.A. Moreira et al.   NEUROSCIENCE

Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats

(2011) Natale R. Sciolino et al.   PHARMACOLOGICAL RESEARCH

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

Prefrontal control of fear: more than just extinction

(2010) Francisco Sotres-Bayon et al.   CURRENT OPINION IN NEUROBIOLOGY

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

The Endocannabinoid 2-Arachidonoylglycerol Produced by Diacylglycerol Lipase α Mediates Retrograde Suppression of Synaptic Transmission

(2010) Asami Tanimura et al.   NEURON

Different role of the ventral medial prefrontal cortex on modulation of innate and associative learned fear

(2010) S.F. Lisboa et al.   NEUROSCIENCE

Activity in prelimbic cortex is required for adjusting the anxiety response level during the elevated plus-maze retest

(2010) C.A.J. Stern et al.   NEUROSCIENCE

Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

(2010) Steven G. Kinsey et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Inhibitors of Endocannabinoid-Metabolizing Enzymes Reduce Precipitated Withdrawal Responses in THC-Dependent Mice

(2009) Joel E. Schlosburg et al.   AAPS Journal

Molecular Reconstruction of mGluR5a-Mediated Endocannabinoid Signaling Cascade in Single Rat Sympathetic Neurons

(2009) Y.-J. Won et al.   JOURNAL OF NEUROSCIENCE

Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator

(2009) Daniele Cristina Aguiar et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey

(2009) V. A. Mitchell et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endocannabinoids contribute to metabotropic glutamate receptor-mediated inhibition of GABA release onto hippocampal CA3 pyramidal neurons in an isolated neuron/bouton preparation

(2009) H. Inada et al.   NEUROSCIENCE

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

(2009) J. Z. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats

(2009) Daniele C. Aguiar et al.   PSYCHOPHARMACOLOGY

Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous System

(2008) Kay Ahn et al.   CHEMICAL REVIEWS

Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test

(2008) Sabrina F. Lisboa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anxiolytic Effects in Mice of a Dual Blocker of Fatty Acid Amide Hydrolase and Transient Receptor Potential Vanilloid Type-1 Channels

(2008) Vincenzo Micale et al.   NEUROPSYCHOPHARMACOLOGY

Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats

(2008) L. B. M. Resstel et al.   PSYCHOPHARMACOLOGY

Modulation of defensive responses and anxiety-like behaviors by group I metabotropic glutamate receptors located in the dorsolateral periaqueductal gray

(2007) Vivian C.F. Lima et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY